Journals / Turkish Journal of Pediatrics / 2020 / Cilt: 62 - Sayı: 6

Is being small for gestational age a risk factor for strabismus and refractive errors at 3 years of age?

Pages
1049–1057
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We concluded that SGA seems to be associated with an increased risk of strabismus and a high refractive error.

📌 3 Key Takeaways

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Objective & Hypothesis:Visual problems, cerebral visual impairment, refractive errors and strabismus are commonly found in preterm infants in long-term follow-ups.
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Key Findings & Data:We retrospectively evaluated children who were screened for retinopathy of prematurity (ROP) and who had a 3rd year ophthalmologic examination.
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Conclusion & Impact:We concluded that SGA seems to be associated with an increased risk of strabismus and a high refractive error.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Background. Visual problems, cerebral visual impairment, refractive errors and strabismus are commonly found in preterm infants in long-term follow-ups. The aim of this study was to determine the factors that lead to the development of amblyogenic risk factors, such as high refractive errors, anisometropia and strabismus, in the long-term evaluation of preterm infants.Methods. We retrospectively evaluated children who were screened for retinopathy of prematurity (ROP) and who had a 3rd year ophthalmologic examination. The impacts of sex, gestational age (GA), birth weight (BW), BW for GA, being small for gestational age (SGA), being appropriate for gestational age (AGA), multiple pregnancies and the results of ROP screening on refractive errors and the development of strabismus were evaluated by logistic regression analysis. The SGA and AGA groups were compared in terms of refractive errors and presence of strabismus. Results. Six hundred and eight children, including 317 (52.1%) males and 291 (47.9%) females, were included in the study. The mean GA was 31 ± 3 weeks (24-36), and the mean BW was 1505 ± 435 g (600-2460). The number of SGA-born children was 101 (16.6%). Manifest deviation was detected in 42 (5.6%) children, and optical correction was required in 101 (16.6%) children. Being an SGA infant and multiple pregnancies were risk factors for refractive errors requiring optical correction, and hyperopia (≥3.00 D) was found to be a risk factor for the development of strabismus in the multivariate regression analysis. Additionally, the SGA group was at high risk for strabismus, hyperopia, high astigmatism and the need for optical correction.Conclusions. We concluded that SGA seems to be associated with an increased risk of strabismus and a high refractive error. It should be taken into consideration during follow-up examinations of SGA infants

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Cite This Article

PETRİÇLİ, İ. S., KARA, C., ARMAN, A. (2020). Is being small for gestational age a risk factor for strabismus and refractive errors at 3 years of age?. Turkish Journal of Pediatrics, Cilt: 62 - Sayı: 6, 1049–1057. https://ajindex.com/articles/411909

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References (13)

  1. O’Connor AR, Wilson CM, Fielder AR. Ophthalmological problems associated with preterm birth. Eye (Lond) 2007; 21: 1254-1260
  2. Al Oum M, Donati S, Cerri L, Agosti M, Azzolini C. Ocular alignment and refraction in preterm children at 1 and 6 years old. Clin Ophthalmol 2014; 8: 1263- 1268
  3. Choi MY, Park IK, Yu YS. Long term refractive outcome in eyes of preterm infants with and without retinopathy of prematurity: comparison of keratometric value, axial length, anterior chamber depth, and lens thickness. Br J Ophthalmol 2000; 84: 138-143
  4. O’Connor AR, Stephenson TJ, Johnson A, Tobin MJ, Ratib S, Fielder AR. Strabismus in children of birth weight less than 1701 g. Arch Ophthalmol 2002; 120: 767-773
  5. Cotter SA, Varma R, Tarczy-Hornoch K, et al; Joint Writing Committee for the Mul-ti-Ethnic Pediatric Eye Disease Study and the Baltimore Pediatric Eye Disease Study Groups Risk factors associated with childhood strabismus: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology 2011; 118: 2251-2261
  6. Gulati S, Andrews CA, Apkarian AO, Musch DC, Lee PP, Stein JD. Effect of gestational age and birth weight on the risk of strabismus among premature infants. JAMA Pediatr 2014; 168: 850-856
  7. Holmstrom M, el Azazi M, Kugelberg U. Ophthalmological long-term follow up of preterm infants: a population based, prospective study of the refraction and its development. Br J Ophthalmol 1998; 82: 1265-1271
  8. Saw SM, Tong L, Chia KS, et al. The relation between birth size and the results of refractive error and biometry measurements in children. Br J Ophthalmol 2004; 88: 538-542
  9. Lim LS, Chua S, Tan PT, et al. Eye size and shape in newborn children and their relation to axial length and refraction at 3 years. Ophthal Physl Opt 2015; 35: 414-423
  10. Mutti DO, Mitchell GL, Jones LA, et al. Axial growth and changes in lenticular and corneal power during emmetropization in infants. Invest Ophthalmol Vis Sci 2005; 46: 3074-3080
  11. Boghossian NS, Geraci M, Edwards EM, Horbar JD. Morbidity and mortality in small for gestational age infants at 22 to 29 weeks’ gestation. Pediatrics 2018; 141: e20172533
  12. Qiu X, Lodha A, Shah PS, et al; Canadian Neonatal Network Neonatal outcomes of small for gestational age preterm infants in Canada. Am J Perinatol 2012; 29: 87-94
  13. Allegaert K, Vanhole C, Casteels I, et al. Perinatal growth characteristics and associated risk of developing threshold retinopathy of prematurity. J AAPO