SavedAdd your journal

Journals / Turkish Journal of Gastroenterology / 2014 / Cilt: 25 - Sayı: 5

Comparison of efficacies of vegetable oil based and polyethylene glycol based bisacodyl suppositories in treating patients with neurogenic bowel dysfunction after spinal cord injury: A meta-analysis

Zhu Yİ
Cheng JİE
Zhang WENYİ
Xie BİN
Jin HONGZHU
Pages
488–492
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Based on the results, we conclude that the PGB suppository could act faster than the VOB suppository in the treatment of NBD in patients with SCI.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/Aims: We performed a meta-analysis to compare the efficacies of vegetable oil based bisacodyl (VOB) and polyethylene glycol based bisacodyl (PGB) suppositories in treating patients with neurogenic bowel dysfunction (NBD) after spinal cord injury (SCI).
📊
Key Findings & Data:Materials and Methods: Relevant clinical studies (up to February 2014) were retrieved through the following databases: PubMed, MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CCTR), Chinese National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), Wanfang, and VIP database for Chinese Technical Periodicals.
💡
Conclusion & Impact:Conclusion: Based on the results, we conclude that the PGB suppository could act faster than the VOB suppository in the treatment of NBD in patients with SCI.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Özet

Background/Aims: We performed a meta-analysis to compare the efficacies of vegetable oil based bisacodyl (VOB) and polyethylene glycol based bisacodyl (PGB) suppositories in treating patients with neurogenic bowel dysfunction (NBD) after spinal cord injury (SCI). Materials and Methods: Relevant clinical studies (up to February 2014) were retrieved through the following databases: PubMed, MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CCTR), Chinese National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), Wanfang, and VIP database for Chinese Technical Periodicals. Data were analyzed using the standardized weighted mean difference (SMD) and its 95% confidence interval (CI). P-values <0.05 were considered statistically significant. Results: A total of 3 studies were included in the meta-analysis. The SMD and its 95% CI were not calculated owing to unreported standard deviations in the individual studies. The average and p-values of statistical difference indicated that the total bowel care time (p<0.05), time to flatus (p<0.05), and defecation period (p<0.05) were shorter in patients treated with PGB than in patients treated with VOB. No significant difference was observed in time to clean up (p>0.05) between patients in the PGB and VOB groups. Conclusion: Based on the results, we conclude that the PGB suppository could act faster than the VOB suppository in the treatment of NBD in patients with SCI.

🔖

Cite This Article

Yİ, Z., JİE, C., WENYİ, Z., BİN, X., HONGZHU, J. (2014). Comparison of efficacies of vegetable oil based and polyethylene glycol based bisacodyl suppositories in treating patients with neurogenic bowel dysfunction after spinal cord injury: A meta-analysis. Turkish Journal of Gastroenterology, Cilt: 25 - Sayı: 5, 488–492. https://ajindex.com/articles/409536

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Richards JS, Kewman DG, Pierce CA. Spinal cord injury. In: Frank FG, Elliott TR. Handbook of Rehabilitation Psychology. Washing- ton, DC: American Psychological Association; 2000.p.11-27.
  2. Hocevar B, Gray M. Intestinal diversion (colostomy or ileostomy) in patients with severe bowel dysfunction following spinal cord injury. J Wound Ostomy Continence Nurs 2008; 35: 159-66. Schwab ME. Repairing the injured spinal cord. Science 2002; 295: 1029-31.
  3. Lynch AC, Wong C, Anthony A, Dobbs BR, Frizelle FA. Bowel dys- function following spinal cord injury: a description of bowel func- tion in a spinal cord-injured population and comparison with age and gender matched controls. Spinal Cord 2000; 38: 717-23.
  4. Menter R, Weitzenkamp D, Cooper D, Bingley J, Charlifue S, Whit- eneck G. Bowel management outcomes in individuals with long- term spinal cord injuries. Spinal Cord 1997; 35: 608-12.
  5. Stiens SA, Bergman SB, Goetz LL. Neurogenic bowel dysfunction after spinal cord injury: clinical evaluation and rehabilitative man- agement. Arch Phys Med Rehabil 1997; (3 Suppl) 78: S86-102. Ayaş S, Leblebici B, Sözay S, Bayramoğlu M, Niron EA. The effect of abdominal massage on bowel function in patients with spinal cord injury. Am J Phys Med Rehabil 2006; 85: 951-5.
  6. Zhang X, Liu S, Hu T, Liu S, He Y, Sun S. Up-regulated microR- NA-143 transcribed by nuclear factor kappa B enhances hepa- tocarcinoma metastasis by repressing fibronectin expression. Hepatology 2009; 50: 490-9.
  7. Liu CW, Huang CC, Yang YH, Chen SC, Weng MC, Huang MH. Re- lationship between neurogenic bowel dysfunction and health- related quality of life in persons with spinal cord injury. J Rehabil Med 2009; 41: 35-40.
  8. Glickman S, Kamm M. Bowel dysfunction in spinal-cord-injury pa- tients. Lancet 1996; 347: 1651-3.
  9. Benevento BT, Sipski ML. Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. Phys Ther 2002; 82: 601-12.
  10. Preziosi G, Emmanuel A. Neurogenic bowel dysfunction: Patho- physiology, clinical manifestations and treatment. Expert Rev Gastroenterol Hepatol 2009; 3: 417-23.
  11. Tsai P-Y, Wang C-P, Chiu F-Y et al. Efficacy of functional magnetic stimulation in neurogenic bowel dysfunction after spinal cord in- jury. J Rehabil Med 2009; 41: 41-7.
  12. Stiens SA, Luttrel W, Binard JE. Polyethylene glycol versus vegeta- ble oil based bisacodyl suppositories to initiate side-lying bowel care: A clinical trial in persons with spinal cord injury. Spinal Cord 1998; 36: 777-81.
  13. Ikarashi N, Baba