Journals / Turkish Journal of Pharmaceutical Sciences / 2010 / Cilt: 7 - Sayı: 2

Bilecik ilinde geleneksel tıp ve seçilmiş türlerin antimikrobiyal aktivitesi

Traditional medicine in Bilecik province (Turkey) and antimicrobial activities of selected species

Pages
139–150
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results indicate that the ethanolic extracts of L. stoechas subsp. cariensis and P. major have shown the strongest activity against Staphylococcus aureus with a MIC value of 19.52 pig/ml.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Traditional medicine in North-West of Turkey (Bilecik province) was studied during a three-month field study by interviewing local informants from several districts. 64 plant samples belonging to 33 families were recorded to be used in the treatment of 26 different diseases mainly for gastrointestinal disorders (18%), respiratory disorders (11%), rheumatism (15%) and skin disorders (8%).
📊
Key Findings & Data:Petroleum ether and ethanol extracts were prepared from the aerial parts of Hedera helix, Lavandula stoechas subsp. cariensis, Plantago major, Teucrium chamaedrys subsp. chamaedrys and Teucrium polium and tested in vitro against 7 bacterial and one fungal strains using microbroth dilution technique according to Clinical and Laboratory Standards Institute (CLSI).
💡
Conclusion & Impact:The results indicate that the ethanolic extracts of L. stoechas subsp. cariensis and P. major have shown the strongest activity against Staphylococcus aureus with a MIC value of 19.52 pig/ml.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Traditional medicine in North-West of Turkey (Bilecik province) was studied during a three-month field study by interviewing local informants from several districts. 64 plant samples belonging to 33 families were recorded to be used in the treatment of 26 different diseases mainly for gastrointestinal disorders (18%), respiratory disorders (11%), rheumatism (15%) and skin disorders (8%). Uses of Cionura erecta, Echium plantagineum, Neslia apiculata, Stachys thirkei, Oxalis articulata, Consolida regalis subsp. paniculata and Solanum alatum in traditional medicine have been reported for the first time herein. The plant species used to treat infections and skin disorders were tested for antimicrobial activity. Petroleum ether and ethanol extracts were prepared from the aerial parts of Hedera helix, Lavandula stoechas subsp. cariensis, Plantago major, Teucrium chamaedrys subsp. chamaedrys and Teucrium polium and tested in vitro against 7 bacterial and one fungal strains using microbroth dilution technique according to Clinical and Laboratory Standards Institute (CLSI). The results indicate that the ethanolic extracts of L. stoechas subsp. cariensis and P. major have shown the strongest activity against Staphylococcus aureus with a MIC value of 19.52 pig/ml. The petroleum ether extracts of T polium and T chamaedrys subsp. chamaedrys have exhibited moderate activity against Klebsiella pneumoniae (MIC: 156.2 ng/ml). None of the extracts tested have shown antifungal activity against C albicans.

Özet

Kuzeybatı Türkiye (Bilecik ili) geleneksel ilaçları, 3 aylık bir arazi çalışması süresince çeşitli ilçelerden yerel bilgi veren kimseler ile görüşülerek çalışılmıştır. 33 familyaya ait 64 bitki örneğinin başlıca gastro-intestinal sistem rahatsızlıklar (18%)), solunum sistemi rahatsızlıkları (11%), romatizma (15%) ve deri hastalıkları (8%) olmak üzere 26 farklı hastalığın tedavisinde kullanıldığı kaydedilmiştir. Cionura erecta, Echium plantagineum, Neslia apiculata, Stachys thirkei, Oxalis articulata, Consolida regalis subsp. paniculata ve Solanum alatum'un geleneksel ilaç olarak tıbbi kullanılışları ilk kez bildirilmiştir. Enfeksiyonları tedavi etme ve deri hastalıklarında kullanılan bitki türleri antimikrobiyal aktiviteleri bakımından test edilmiştir. Hedera helix, Lavandula stoechas subsp. cariensis, Plantago major, Teucrium chamaedrys subsp. chamaedrys ve Teucrium polium 'un topraküstü kısımlarından petrol eteri ve etanol ekstreleri hazırlanmış ve antimikrobiyal aktiviteleri 7 bakteri ve bir mantar suşuna karşı CLSI'ya göre dilüsyon tekniği kullanılarak in vitro olarak test edilmiştir. Sonuçlar L. stoechas subsp. cariensis ve P. major etanol ekstrelerinin Staphylococcus aureus'a karşı 19.52 jug/ml MİK değeri ile en kuvvetli aktiviteyi gösterdiğini belirtmektedir. T. polium ve T. chamaedrys subsp. chamaedrys petrol eteri ekstreleri Klebsiella pneumoniae'ye karşı orta derecede aktivite (MİK: 156.2 /ıg/ml) göstermiştir. Ekstrelerin hiçbiri Candida albicans 'a karşı antifungal aktivite göstermemiştir.

🔖

Cite This Article

ÜNSAL, Ç., VURAL, H., Sarıyar, G., ÇELİK, B. Ö., ÖTÜK, G. (2010). Bilecik ilinde geleneksel tıp ve seçilmiş türlerin antimikrobiyal aktivitesi. Turkish Journal of Pharmaceutical Sciences, Cilt: 7 - Sayı: 2, 139–150. https://ajindex.com/articles/404103

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution antifungal susceptibility testing of yeasts, Approved Standard, M27-A, Wayne, Pennsylvania, 2000
  2. Clinical and Laboratory Standards Institute (CLSI). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, Approved Standard, M7-A5 Wayne, Pennsylvania, 2006
  3. Baytop, T., A dictionary of vernacular names of wild plants of Turkey. Publication of the Turkish Language Society, No: 578, Ankara, 1997
  4. Baytop, T., Therapy with plants in Turkey: Past and present. Istanbul University Publications, No: 3255, İstanbul, 1984
  5. Uzun, E., Sarıyar, G., Adsersen, A., Karakoç, B., Ötük, G., Oktayoğlu, E., Pırıldar, S., “Traditional medicine in Sakarya province (Turkey) and antimicrobial activities of selected species” J. Ethnopharmacol., 95, 287-296, 2004
  6. Moon, T., Wilkinson, J.M., Cavanagh, H.M.A., “Antibacterial activity of essential oils, hydrosols and plant extracts from Australian grown Lavandula spp.” Int. J. Ess. Oil Ther., 16, 9-14, 2006
  7. Samuelsen, A.B., “The traditional uses, chemical constituents and biological activities of Plantago major L. A review” J. Ethnopharmacol., 71, 1-21, 2000
  8. Kabouche, Z., Boutaghane, N., Laggoune, S., Kabouche, A., Ait-Kaki, Z., Benlabed, K., “Comparative antibacterial activity of five Lamiaceae essential oils from Algeria” Int. J. Ess. Oil Ther., 15, 129-133, 2005
  9. Küçük, M., Güleç, C., Yaşar, A., Üçüncü, O., Yaylı, N., Coşkunçelebi, K., Terzioğlu, S., Yaylı, N., “Chemical composition and antimicrobial activities of the essential oils of Teucrium chamaedrys subsp. chamaedrys, T. orientale var. puberulens and T. chamaedrys subsp. lydium” Pharm. Biol., 44(8), 592-599, 2006.