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Journals / Turkish Journal of Pharmaceutical Sciences / 2007 / Cilt: 4 - Sayı: 2

Türkiye'de yetişen bir liken türü olan Cladonia rangiformis'in antioksidan ve antimikrobiyal özellikleri

Antioxidant and antimicrobial properties of a lichen species, Cladonia rangiformis growing in Turkey

Osman YÜCEL
Fehmi ODABAŞIOĞLU
MEDİNE GÜLLÜCE
Z.Zeki ÇALIK
Ahmet ÇAKIR
Ali ASLAN
KENAN YAZICI
MESUT BÜNYAMİ HALICI
Pages
101–109
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, extracts showed no antifungal activity

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The antioxidant activity (AA), reducing power (RP) and total phenolic compounds (TPC) of chloroform, methanol and water extracts of a lichen species, Cladonia rangiformis, was determined, in vitro.
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Key Findings & Data:The chloroform extract of C. rangiformis showed significant antioxidant activity (p<0.05), although this activity was lower than that of trolox (positive control).
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Conclusion & Impact:However, extracts showed no antifungal activity
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Likenler · Antioksidanlar · In vitro

Abstract

The antioxidant activity (AA), reducing power (RP) and total phenolic compounds (TPC) of chloroform, methanol and water extracts of a lichen species, Cladonia rangiformis, was determined, in vitro. The chloroform extract of C. rangiformis showed significant antioxidant activity (p<0.05), although this activity was lower than that of trolox (positive control). Likewise, the chloroform extract of C. rangiformis contained the highest phenolic content as gallic acid equivalent (µg/ml-1), its followed by the methanol and water extracts. However the reducing power assay of the methanol extract of C. rangiformis was higher than chloroform and water extracts. Antimicrobial activities of these extracts against 42 microorganisms consisting of 26 bacterial strains, 15 fungi and a yeast were also studied by using disk diffusion method. The extracts exhibited a weak antimicrobial activity against very limited number of microorganisms. However, extracts showed no antifungal activity

Özet

Bir liken türü olan Cladonia rangiformis’in kloroform, metanol ve sulu ekstrelerinin in vitro antioksidan aktivitesi (AA), indirgeme güçleri (RP) ve toplam fenolik madde içerikleri (TPC) belirlenmiştir. C. rangiformis’in kloroformlu ekstresi troloks’tan (pozitif kontrol) daha düşük olmasına rağmen önemli bir antioksidan aktivite göstermiştir (p<0.05). Aynışekilde C. rangiformis’in kloroformlu ekstresi gallik asit eşdeğeri (µg/ml-1) olarak en yüksek fenolik içeriğine sahip olup bunu metanol ve su ekstreleri izlenmiştir. Diğer yandan C. rangiformis’in metanolül ekstresinin indirgeme gücü kloroform ve metanol ekstrelerinden daha yüksek bulunmuştur. Bu ekstrelerin antimikrobiyal aktiviteleride 26 bakteri suşu, 15 fungus ve bir maya’dan oluşan 42 mikroorganizmaya karşıdisk-diffüzyon yöntemi kullanılarak çalışılmıştır. Ekstreler az sayıda mikroorganizmaya karşı zayıf bir antimikrobiyal aktivite gösterdi. Bununla beraber, ekstreler hiç antifungal etki göstermiştir.

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Cite This Article

YÜCEL, O., ODABAŞIOĞLU, F., GÜLLÜCE, M., ÇALIK, Z., ÇAKIR, A., ASLAN, A., YAZICI, K., HALICI, M. B. (2007). Türkiye'de yetişen bir liken türü olan Cladonia rangiformis'in antioksidan ve antimikrobiyal özellikleri. Turkish Journal of Pharmaceutical Sciences, Cilt: 4 - Sayı: 2, 101–109. https://ajindex.com/articles/403851

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References (19)

  1. Andlauer, W., Furst, P., “Antioxidative power of phytochemicals with special reference to cereals” Cereal Foods World, 43, 356 –359, 1998
  2. Grice, HC., “Safety evaluation of butylated hydroxytoluene (BHT) in the liver, lung and gastrointestinal tract” Food and Chemical Toxicology, 24, 1127-1130, 1986
  3. Rice-Evans, C.A., Miller, N.J., Paganga, G., “Antioxidant properties of phenolic compounds” Trend in Plant Science, 2, 152-159, 1997
  4. Jayaprakasha, G.K., Jaganmohan, R.L., “Phenolic constituents from the lichen, Parmotrema stuppeum Hale and their antioxidant activity” Zeitsch Fur Naturf., 55, 1018- 1022, 2000
  5. Ahmadjian, V., The Lichen Symbiosis. Wiley, New York,1993
  6. Vartia, K.O., Antibiotics in Lichens. Academic Press, New York, 1974
  7. Rundel, P.W., “The ecological role of secondary lichen substances” Biochem Syst Ecol., 6,157–170, 1978
  8. Lawrey, JD., “Biological role of lichen substances” Bryologist, 89, 111–122, 1986
  9. Lawrey, J.D., “Lichen secondary compounds: evidence for a correspondence between antiherbivore and antimicrobial function” Bryologist, 92: 326–328, 1989
  10. Richardson, D.H.S., Medicinal and Other Economic Aspects of Lichens. Vol III, CRC Press, Boca Raton, 1988
  11. Richardson, D.H.S., Lichens and Man. CAB International, Wallingford, 1991
  12. Huneck S., “The significance of lichens and their metabolites” Naturwissenschaften, 86, 559-570, 1999
  13. Honda, N.K., Vilegas W., “The Chemistry of Lichens” Quimica Nova, 22, 110-125, 1999
  14. Aslan, A., Güllüce, M., Öğütçü, H., “An investigation on the antimicrobial activity of some lichens” Biyoteknoloji (Kukem) Dergisi, 22, 19-26, 1999
  15. Hidalgo, M.E., Fernandez, E., Quilhot, W., Lissi, E., “Antioxidant activity of depsides and depsidones” Phytochemistry, 37, 1585-1587, 1994
  16. Caviglia, A.M., Nicora, P., Giordani, P., Brunialti, G., Modenesi, P., “Oxidative stress and usnic acid content in Parmelia caperata and Parmelia soredians (lichens)” Il Farmaco, 56, 379-382, 2001
  17. Gülçin, I., Oktay, M., Küfrevioğlu, O.I., Aslan, A., “Determination of antioxidant activity of lichen Cetraria islandica (L) Ach.” J Ethnopharmacology, 79, 325-329, 2002
  18. Odabaşoğlu, F., Aslan, A., Çakır, A., Süleyman, H., Karagöz, Y., Halıcı, M., Bayır, Y., “Comparison of antioxidant activity and phenolic content of three lichen species” Phytother. Res., 18: 938–941
  19. Dülger, B., Gucin, F., Kara, A., Aslan, A., “Usnea florida(L.) Wigg. likeninin antimikrobiyal aktivitesi” Turkish J Biol