Journals / Turkish Journal of Surgery / 2018 / Cilt: 34 - Sayı: 2

Hyalinizing trabecular tumor of the thyroid gland

Pages
149–151
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, diagnosis, treatment, and follow-up steps of Hyalinizing trabecular tumor should be plannedin consideration of a malignant potential.

📌 3 Key Takeaways

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Objective & Hypothesis:Hyalinizing trabecular tumor was first described by Carney et al. (1) in 1987 and is a rare benign tumor of thethyroid gland that shares some of the microscopic features of medullary and papillary thyroid carcinoma.
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Key Findings & Data:In this study, we present the case of a 40-year-old female patient with thyroid glandnodules, whose ultrasound results, clinical behavior, and fine-needle aspiration biopsy results were suspicious;the pathology after thyroidectomy indicated hyalinizing trabecular tumor.
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Conclusion & Impact:Therefore, diagnosis, treatment, and follow-up steps of Hyalinizing trabecular tumor should be plannedin consideration of a malignant potential.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Hyalinizing trabecular tumor was first described by Carney et al. (1) in 1987 and is a rare benign tumor of thethyroid gland that shares some of the microscopic features of medullary and papillary thyroid carcinoma. Hyalinizingtrabecular tumor derives from follicular cells, and it is characterized by an apparent trabecular pattern andintratrabecular hyalinization. In this study, we present the case of a 40-year-old female patient with thyroid glandnodules, whose ultrasound results, clinical behavior, and fine-needle aspiration biopsy results were suspicious;the pathology after thyroidectomy indicated hyalinizing trabecular tumor. We aimed to show the role of clinicalbehavior, radiology, fine-needle aspiration, and histological and immunohistochemical analysis in the differentialdiagnosis of hyalinizing trabecular tumor. Hyalinizing trabecular tumor which can be confused with papillary andmedullar carcinoma of the thyroid gland, is mostly benign but some malignant and metastatic cases have beenreported. Therefore, diagnosis, treatment, and follow-up steps of Hyalinizing trabecular tumor should be plannedin consideration of a malignant potential.

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Cite This Article

ERGUN, S., AKINCI, O., ÖZTÜRK, T., KARATAŞ, A. (2018). Hyalinizing trabecular tumor of the thyroid gland. Turkish Journal of Surgery, Cilt: 34 - Sayı: 2, 149–151. https://ajindex.com/articles/390474

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References (2)

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  2. Gowrishankar S, Pai SA, Carney JA. Hyalinizing trabecular carcinoma of the thyroid gland. Histopathology 2008; 52: 529- 531. [CrossRef] Nose` V, Volante M, Papotti M. Hyalinizing trabecular tumor of the thyroid: an update. Endocr Pathol 2008; 19: 1-8. [CrossRef] Fonseca E, Nesland JM, Sobrinho-Simões M. Expression of stratified epithelial-type cytokeratins in hyalinizing trabecular adenomas supports their relationship with papillary carcinomas of the thyroid. Histopathology 1997; 31: 330-335. [CrossRef] Katoh R, Jasani B, Williams ED. Hyalinizing trabecular adenoma of the thyroid. A report of three cases with immunohistochemical and ultrastructural studies. Histopathology 1989; 15: 211- 224. [CrossRef] De Micco C, Savchenko V, Giorgi R, Sebag F, Henry JF. Utility of malignancy markers in fine-needle aspiration cytology of thyroid nodules: comparison of Hector Battifora mesothelial antigen-1, thyroid peroxidase and dipeptidyl aminopeptidase IV Br J Cancer 2008; 98: 818-823. [CrossRef] Carney JA, Hirokawa M, Lloyd RV, Papotti M, Sebo TJ Hyalinizing trabecular tumors of the thyroid gland are almost all benign. Am J Surg Pathol 2008; 32: 1877-1889. [CrossRef]