Journals / Ankara Üniversitesi Eczacılık Fakültesi Dergisi / 1987 / Cilt: 17 - Sayı: 1

Effect of Rutin on the Isolated Rat Duodenum and Comparison with the Effects of Adrenaline, Isoprenaline and Papaverine

Rutin'i n İzole Sıçan Duodenum u Üzerine Etkisi ve Adrenalin, İzoprenalin, Papaverin ile Karşılaştırılması.

Pages
0–0
Publication Date
1987-06-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, propranolol, a beta-adrener - gic blocking agent, phentolamine , an alpha-adrenergi c blockingagent a n d nicotinic acid, an adenyl cyclase inhibitor were used as tools to investigate mechanism of the relaxant effect of rutin on the ra t duo - denu m in vitro.

📌 3 Key Takeaways

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Objective & Hypothesis:T h e experiments were performed by using isolated ra t duodenum .
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Key Findings & Data:Rutin, a natura l flavonoid compound , caused relaxations of the ra t duodenu m dose-dependently.
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Conclusion & Impact:In addition, propranolol, a beta-adrener - gic blocking agent, phentolamine , an alpha-adrenergi c blockingagent a n d nicotinic acid, an adenyl cyclase inhibitor were used as tools to investigate mechanism of the relaxant effect of rutin on the ra t duo - denu m in vitro.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anahtar Kelimeler Rutin · Adrenaline · Isoprenaline

Abstract

T h e experiments were performed by using isolated ra t duodenum . Rutin, a natura l flavonoid compound , caused relaxations of the ra t duodenu m dose-dependently. Th e relaxant effect of rutin on the ra t duodenu m was examined in comparison with tha t of adrenaline , isoprenaline and papaverine . In addition, propranolol, a beta-adrener - gic blocking agent, phentolamine , an alpha-adrenergi c blockingagent a n d nicotinic acid, an adenyl cyclase inhibitor were used as tools to investigate mechanism of the relaxant effect of rutin on the ra t duo - denu m in vitro.

Özet

Deneyler izole sıçan duodenum u kullanılarak sürdürüldü. Doğa l bir flavonoid bileşiği olan rutin doza bağımlı biçimde sıçan duodenumun u gevşetti. Rutin'i n sıçan duodenumundak i gevşetici etkisi adrenalin, izoprenalin ve papaverin ile karşılaştırmalı olarak incelendi. Ayrıca, rutin'in sıçan duodenumundak i gevşetici etkisinin mekaniz - masını araştırmak için beta-adrenerjik bloker olan propranolol, alfaadrenerjik bloker olan fentolamin ve bir adenil siklaz inhibitörü olan nikotinik asid de kullanıldı.

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Cite This Article

ALTINKURT, O., ÖZTÜRK, Y. (1987). Effect of Rutin on the Isolated Rat Duodenum and Comparison with the Effects of Adrenaline, Isoprenaline and Papaverine. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, Cilt: 17 - Sayı: 1, 0–0. https://ajindex.com/articles/38812

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