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Journals / Toraks Dergisi / 2006 / Cilt: 7 - Sayı: 1

The diagnostic productivity of the novel biochemical formulas in the differentiating exudative from transudative pleural effusions

Plevral sıvılarda transuda-eksuda ayrımında yeni biyokimyasal formüllerin tanısal verimliliği

Özgür USLU
Fevziye TUKSAVUL
Nalan Işık KABAKOĞLU
Mehmet GÜLPEK
Melike KAZANCI
Salih Zeki GÜÇLÜ
Pages
34–39
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this context, following studies performed with large series and meta-analysis, it likely to replace Light’s criteria by Kokturk formula in the future.

📌 3 Key Takeaways

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Objective & Hypothesis:The sensitivity and specificity of Light’s criteria was found as 100% and 74%, respectively.
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Key Findings & Data:The sensitivity and specificity of Kokturk formula 1, 2 and 3 was 98% and 91%, 95% and 94%, and 96% and 94%, respectively.
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Conclusion & Impact:In this context, following studies performed with large series and meta-analysis, it likely to replace Light’s criteria by Kokturk formula in the future.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Plevral efüzyon · Duyarlılık ve özgüllük · Eksuda ve transüdalar

Abstract

The sensitivity and specificity of Light&#8217;s criteria was found as 100% and 74%, respectively. The sensitivity and specificity of Kokturk formula 1, 2 and 3 was 98% and 91%, 95% and 94%, and 96% and 94%, respectively. Yildiz 1 formula offered 93% sensitivity and %94 specificity. The sensitivity and specificity of Yildiz formula 2 and 3 were found to be equal with 95% and 91%, respectively. The specificity of Kokturk formula 1, 2 and 3 was significantly higher than Light criteria (both, p<0.05). The sensitivity was also significantly higher in Kokturk formula 1, 2 and 3 than the serum to pleural fluid albumin gradient between and (both, p<0.05). The sensitivity of Light&#8217;s criteria was significantly higher than Yildiz formula 1, 2 and 3 (both, p<0.05), while the specificity was significantly lower (both, p<0.05). In addition to recent reports, we also showed that Kokturk formulas are superior to Light&#8217;s criteria in differentiating exudative from transudative pleural effusion. In this context, following studies performed with large series and meta-analysis, it likely to replace Light&#8217;s criteria by Kokturk formula in the future.

Özet

Çalışmamızda Light kriterleri kullanıldığında duyarlılık %100 ve özgüllük %74 olarak bulundu. Köktürk formülleri uygulandığında ise Formül 1’in duyarlılığı %98, özgüllüğü %91 bulundu. Formül 2 ve Formül 3’ün duyarlılığı sırasıyla %95 ve %96, her iki formülün özgüllüğü %94 olarak hesaplandı. Yıldız formülleri kullanıldığında Formül 1’in duyarlılığı %93, özgüllüğü %94 bulundu. Formül 2 ve Formül 3’ün duyarlılığı ve özgülüğü aynı bulundu, sırasıyla %95 ve %91. Köktürk formüllerinin üçünün de özgüllüğü Light kriterlerinden, duyarlılığı ise albumin gradientinden istatistiksel olarak daha yüksek bulundu (p< 0.05). Light kriterleri ile Yıldız formülleri karşılaştırıldığında ise Light kriterleri duyarlılık, Yıldız formülleri ise özgüllük yönünden anlamlı olarak daha üstündü (p<0.05). Gerek bizim çalışmamız gerekse de diğer çalışmalar Köktürk formüllerinin Light kriterlerinden daha üstün olduğunu gösterir niteliktedir. Gelecekte yapılacak daha büyük seriler ve bunların metaanalizleri sonucunda Köktürk formüllerinin Light kriterlerinin yerini alabilmesi ihtimal dahilindedir.

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Cite This Article

USLU, Ö., TUKSAVUL, F., KABAKOĞLU, N. I., GÜLPEK, M., KAZANCI, M., GÜÇLÜ, S. Z. (2006). The diagnostic productivity of the novel biochemical formulas in the differentiating exudative from transudative pleural effusions. Toraks Dergisi, Cilt: 7 - Sayı: 1, 34–39. https://ajindex.com/articles/368079

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