Mortality rates and related factors in respiratory intensive care unit patients

The main conditions independently associated with increased mortality rate were arrhythmias (odds ratio [OR] , 8.10; 95% confidence interval [CI], 2.67 – 24.58; p < 0.05), the need for invasive mechanical ventilation (OR , 6.04; 95% CI, 1.88 – 19.34; p < 0.05), the need for cardiotonic medication (OR: 5.36; %95 CI: 1.67 – 17.22, p<0.05)and ventilator-associated pneumonia (OR: 5-21; 95%CI: 1.54-17.63; p < 0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study is to identify the mortality rates and the influential factors in the respiratory intensive care unit (ICU).

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Key Findings & Data:We prospectively evaluated a total of 150 patients consecutively admitted with respiratory failure between May 2003 and May 2005 in Trakya University Hospital, and 135 patients were enrolled in the study.

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Conclusion & Impact:The main conditions independently associated with increased mortality rate were arrhythmias (odds ratio [OR] , 8.10; 95% confidence interval [CI], 2.67 – 24.58; p < 0.05), the need for invasive mechanical ventilation (OR , 6.04; 95% CI, 1.88 – 19.34; p < 0.05), the need for cardiotonic medication (OR: 5.36; %95 CI: 1.67 – 17.22, p<0.05)and ventilator-associated pneumonia (OR: 5-21; 95%CI: 1.54-17.63; p < 0.05).

🔬Design:Research Article

📍Scope:2003 Verileri

⚙️Variables:Solunum yetmezliği · Ölüm oranı · İleriye dönük çalışma

Abstract

The aim of this study is to identify the mortality rates and the influential factors in the respiratory intensive care unit (ICU). We prospectively evaluated a total of 150 patients consecutively admitted with respiratory failure between May 2003 and May 2005 in Trakya University Hospital, and 135 patients were enrolled in the study. The patients excluded from the study were the ones who died within the first 24 hours of ICU (n: 8), or had malignant diseases (n: 7). Chi-square test and t-test were used to compare hospital survivors with non-survivors, and logistic regression analysis was performed to define independent factors influencing the mortality rates in the hospital. To determine the efficiency of APACHE II, ROC analysis was used. 92 of the patients were male and 43 were female. The mean age was 64.9±12.9 years. The mortality rate was 32.6% (n: 44). The highest mortality rate was in patients with severe pneumonia/sepsis. (54.2%). The main conditions independently associated with increased mortality rate were arrhythmias (odds ratio [OR] , 8.10; 95% confidence interval [CI], 2.67 – 24.58; p < 0.05), the need for invasive mechanical ventilation (OR , 6.04; 95% CI, 1.88 – 19.34; p < 0.05), the need for cardiotonic medication (OR: 5.36; %95 CI: 1.67 – 17.22, p<0.05)and ventilator-associated pneumonia (OR: 5-21; 95%CI: 1.54-17.63; p < 0.05).

Özet

Bu çalışmanın amacı solunum yoğun bakım ünitesinde mortalite oranları ve bunu etkileyen faktörleri belirlemektir. Mayıs 2003 – Mayıs 2005 tarihleri arasında solunum yetmezliği ile başvuran, ardışık toplam 150 hasta Trakya Üniversite Hastanesi Göğüs Hastalıkları bölümünde, ileriye yönelik olarak değerlendirildi. 135 hasta çalışmaya dahil edildi. Çalışma dışı bırakılan hastalar; ilk 24 saat içinde ölenler (n:8) ve malign hastalığı olanlar (n:7) idi. Hastaların 92’si erkek, 43’ü kadın ve yaş ortalaması 64.9 ± 12.9 idi. Mortalite oranı %32.6 (44 hasta) idi. En yüksek mortalite oranı (%54.2) ağır pnömoni/ sepsis olgularında idi. Hastanede ölen ve yaşayanların karşılaştırılmasında t-testi ve ki-kare testi kullanılmıştır. Hastanede ölümü belirleyen bağımsız faktörler lojistik regresyon analizi ile bulunmuştur. Mortalite artışını bağımsız olarak etkileyen durumlar; aritmi varlığı (Odds oranı (OR): 8.10; %95 CI: 2.67 – 24.58, p<0.05), invaziv mekanik ventilasyon gereksinimi (OR: 6.04; %95 CI: 1.88 – 19.34, p<0.05), kardiyotonik ihtiyacı (OR: 5.36; %95 CI: 1.67 – 17.22, p<0.05) ve ventilatör ile ilişkili pnömoni gelişimi (OR: 5.21; %95 CI: 1.54 – 17.63, p<0.05) idi

Keywords

Solunum yetmezliği Ölüm oranı İleriye dönük çalışma Solunum yapay Yoğun bakım üniteleri Respiratory Insufficiency Mortality Prospective Studies Respiration Artificial Intensive Care Units

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Cite This Article

ALTIAY, G., TABAKOĞLU, E., ÖZDEMİR, L., TOKUÇ, B., ÇEVİRME, L., HATİPOĞLU, O. N., ÇAĞLAR, T. (2007). Mortality rates and related factors in respiratory intensive care unit patients. Toraks Dergisi, Cilt: 8 - Sayı: 2, 79–84. https://ajindex.com/articles/367910

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