SavedAdd your journal

Journals / Toraks Dergisi / 2005 / Cilt: 6 - Sayı: 2

Bronchiolitis obliterans organizing pneumonia: Three cases leading to respiratory failure

Bronşiyolitis obliterans organize pnömoni: Solunum yetmezliğiyle seyreden üç olgu

GÜNDENİZ ALTIAY
Osman Nuri HATİPOĞLU
Erhan TABAKOĞLU
Ömer YALÇIN
Tuncay ÇAĞLAR
Pages
170–174
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Interestingly, these three patients were admitted to our clinic with progressive respiratory failure in the same one month period.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Bronchiolitis obliterans organizing pneumonia (BOOP) is an entity of unknown etiology characterized histologically by granulation tissue plugs within the lumens of small airways extending into the alveolar ducts and airways.
📊
Key Findings & Data:We treated them with high dose prednisolone for three days (first day 80 mg q6h, second day 80 mg q8h, third day 80 mg q12h) and continued with 1 mg/kg/d prednisolone.
💡
Conclusion & Impact:Interestingly, these three patients were admitted to our clinic with progressive respiratory failure in the same one month period.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Tedavi sonucu · Solunum yetmezliği

Abstract

Bronchiolitis obliterans organizing pneumonia (BOOP) is an entity of unknown etiology characterized histologically by granulation tissue plugs within the lumens of small airways extending into the alveolar ducts and airways. The typical presenting symptoms and signs are dyspnea, cough, fever, weight loss, and a chest radiograph with single or multiple alveolar opacities. Some cases progress rapidly and have a poor prognosis. We followedup three idiopathic BOOP cases in one month. Pathological diagnosis was based on transbronchial lung biopsy (TBLB) in all of them. The characteristic features of all cases were progressive respiratory failure. We treated them with high dose prednisolone for three days (first day 80 mg q6h, second day 80 mg q8h, third day 80 mg q12h) and continued with 1 mg/kg/d prednisolone. We observed rapid radiological and clinical improvement in all cases. Interestingly, these three patients were admitted to our clinic with progressive respiratory failure in the same one month period.

Özet

Bronşiyolitis obliterans organize pnömoni (BOOP) sebebi bilinmeyen, küçük hava yolları içinde granülasyon dokusuyla karakterize bir durumdur. Tipik başlangıç dispne, öksürük, ateş, kilo kaybı ve göğüs radyografisinde tek veya birden çok opasiteler şeklindedir. Bazı vakalarda hızlı progresyon ve ölüm görülür. Bir aylık süre içinde üç idiyopatik BOOP olgusu izledik. Tüm olgularımızda patolojik tanı bronkoskopi eşliğinde transbronşiyal biyopsiyle konuldu. Olgularımızın ortak özelliği hızlı bir şekilde solunum yetmezliği bulgularının gelişmesiydi. Üç gün yüksek doz steroidle (1. gün 4 x 80 mg, 2. gün 3 x 80 mg, 3. gün 2 x 80 mg prednizolon) tedavi başladık ve 1 mg/kg/gün prednizolonla devam ettik. Tüm olgularımızda hızlı bir klinik ve radyolojik iyileşme izledik. Üç olgunun da bir aylık süre içinde başvurması ve hızla solunum yetmezliği bulgularının görülmesi ilginçti.

🔖

Cite This Article

ALTIAY, G., HATİPOĞLU, O. N., TABAKOĞLU, E., YALÇIN, Ö., ÇAĞLAR, T. (2005). Bronchiolitis obliterans organizing pneumonia: Three cases leading to respiratory failure. Toraks Dergisi, Cilt: 6 - Sayı: 2, 170–174. https://ajindex.com/articles/368233

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. King TE. Bronchiolitis. In: Fishman AP; ed. Fishman’s Pulmonary Diseases and Disorders. 3rd ed. New York: McGraw-Hill; 1998:825-46
  2. Lohr RH, Boland BJ, Douglas WW et al. Organizing pneumonia. Features and prognosis of cryptogenic, secondary, and focal variants. Arch Intern Med 1997;157:1323-9
  3. Epler GR. Bronchiolitis obliterans organizing pneumonia. Semin Respir Infect 1995;10:65-77
  4. Fraser RS, Müller NL, Colman N, Pare PD. Diagnosis of the diseases of the chest. 4th ed. Philadelphia: WB Saunders; 1999:2321-57
  5. Guerry-Force ML, Muller NL, Wright JL et al. A comparison of bronchiolitis obliterans with organizing pneumonia, usual interstitial pneumonia, and small airway disease. Am Rev Respir Dis 1987;135:705-12
  6. Epler GR, Colby TV, McLoud TC et al. Bronchiolitis obliterans organizing pneumonia. N Engl J Med 1985;312:152-8
  7. Essadki O, Grenier P. Bronchiolitis: Computed tomographic findings. J Radiol 1999;80:17-24
  8. Tatar D, Güneº EY, Halilçolar H ve ark. Bronºiolitis obliterans organize pnömoni (4 olgu nedeniyle). Solunum 2002;4:38-44
  9. Cordier JF. Cryptogenic organizing pneumonia. Bronchiolitis obliterans organizing pneumonia. Clin Chest Med 1993;14:677-92
  10. Costabel U, Teschler H, Guzman J. Bronchiolitis obliterans organizing pneumonia (BOOP): The cytological and immunocytological profile of bronchoalveolar lavage. Eur Respir J 1992;5:791-7
  11. Nishimura K, Izumi T, Kitaichi M et al. The diagnostic accuracy of high-resolution computed tomography in diffuse infiltrative lung disease. Chest 1993;104:1449-55
  12. Poletti V, Cazzato S, Minicuci N et al. The diagnostic value of bronchoalveolar lavage and transbronchial lung biopsy in cryptogenic organizing pneumonia. Eur Respir J 1996;9:2513-6
  13. Cordier JF, Loire R, Brune J. Idiopathic bronchiolitis obliterans organizing pneumonia. Definition of characteristic clinical profiles in a series of 16 patients. Chest 1989;96:999-1004
  14. Cohen AJ, King TE Jr, Downey GP. Rapidly progressive bronchiolitis obliterans with organizing pneumonia. Am J Resp Crit Care Med 1994;149:1670-5
  15. Chang J, Han J, Kim DW et al. Bronchiolitis obliterans organizing pneumonia: clinicopathologic review of a series of 45 Korean patients including rapidly progressive form. J Korean Med Sci 2002;17:179-86
  16. Nizami IY, Kissner DG, Visscher DW, Dubaybo BA. Idiopathic bronchiolitis obliterans with organizing pneumonia. An acute and life-threatening syndrome. Chest 1995;108:271-7
  17. Husain SJ, Irfan M, Z