Journals / Tıp Araştırmaları Dergisi / 2011 / Cilt: 9 - Sayı: 2

Severe hypercalcemia and acut renal failure: a case report

Şiddetli hiperkalsemi ve akut böbrek yetmezliği: Olgu sunumu

Pages
141–144
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report the case of a 37 year old admitted to our clinic with acut renal failure and diagnosed with esophagus small cell carcinoma and suspected paratyroid adenoma.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hypercalcemia is a life-threatening disorder.
📊
Key Findings & Data:The most common causes of hypercalcemia are primary hyperparathyroidism and malignancy.
💡
Conclusion & Impact:We report the case of a 37 year old admitted to our clinic with acut renal failure and diagnosed with esophagus small cell carcinoma and suspected paratyroid adenoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hypercalcemia is a life-threatening disorder. The most common causes of hypercalcemia are primary hyperparathyroidism and malignancy. An initial etiologic work-up should include measurement of intact parathyroid hormone, Parathyroid hormone is elevated in primary hyperparathyroidism and suppressed in malignancy-associated hypercalcemia. Aggressive intravenous rehydration is the basic of treatment in severe hypercalcemia and antiresorptive agents, such as calcitonin, bisphosphonates and if necessary hemodialysis. We report the case of a 37 year old admitted to our clinic with acut renal failure and diagnosed with esophagus small cell carcinoma and suspected paratyroid adenoma.

Özet

Hiperkalsemi hayatı tehtid eden bir bozukluktur. En sık primer hiperparatiroidizm ve maligniteye bağlı olarak gelişir. Hiperkalsemi etiyolojisinde başlangıçta intakt paratiroid hormona bakılmalıdır. Paratiroid hormon yükselmiş ise primer hiperparatiroidizm, baskılanmışsa maligniteye bağlı hiperkalsemi düşünülür. ùiddetli hiperkalsemide intravenöz hidrasyon, kalsitonin, bifosfanat gibi antiresorptif ajanlar ve gerekirse hemodiyaliz tedavinin temelini oluşturur. Biz kliniğimize akut böbrek yetmezliği ile başvuran 37 yaşında özofagus küçük hücreli karsinomalı ve şüpheli paratiroid adenomu olan hiperkalsemili bir vakayı sunduk.

🔖

Cite This Article

EMRE, H., SOYORAL, Y. U., DÜLGER, A. C., BEĞENİK, H., ALDEMİR, M. N., ERKOÇ, R. (2011). Severe hypercalcemia and acut renal failure: a case report. Tıp Araştırmaları Dergisi, Cilt: 9 - Sayı: 2, 141–144. https://ajindex.com/articles/361896

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Carroll MF, Schade DS. A practical approach to hypercalcemia. Am Fam Physician. 2003; 67:1959–1966
  2. Clines GA, Guise TA. Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone. Endocr Relat Cancer. 2005; 12:549–583
  3. Lee CT, Yang CC, Lam KK et al. Hypercalcemia in the emergency department. Am J Med Sci. 2006; 331:119-123
  4. Ziegler R. Hypercalcemic crisis. J Am Soc Nephrol 2001; 12:S3–9
  5. Mundy GR, Guise TA. Hypercalcemia of malignancy.Am J Med 1997; 103:134-45
  6. Lourwood DL. The pharmacology and therapeutic utility of bisphosphonates. Pharmacotherapy 1998; 18:779–789
  7. Kawada K, Minami H, Okabe K et al. A multicenter and open label clinical trial of zoledronic acid 4 mg in patients with hypercalcemia of malignancy. Jpn J Clin Oncol. 2005;35:28-33
  8. Wang CC, Chen YC, Shiang JC, Lin SH, Chu P, Wu CC. Hypercalcemic crisis successfully treated with prompt calcium-free hemodialysis. Am J Emerg Med. 2009; 27: 1-3.