Journals / Tıp Araştırmaları Dergisi / 2005 / Cilt: 3 - Sayı: 2

The evaluation of Tc-99m MIBI myocardial perfusion scintigraphy by visual and semi quantitative analysis methods in the diagnosis of coronary artery disease

Tc-99m MIBI myokard perfüzyon sintigrafisinin koroner arter hastalığındaki yerinin görsel ve yarı sayısal analiz yöntemleri ile değerlendirilmesi

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Conclusion: It is concluded that Tc-99m MIBI myocard perfusion SPECT imaging has high sensitivity and specificity in the diagnosis of coronary artery disease and there is no significant difference between visual and semi quantitative analysis but there is statistically significant correlation between semi quantitative values and percentage of coronary artery stenosis.

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Objective & Hypothesis:Purpose: The importance of Tc-99m MIBI myocard perfusion SPECT imaging in the diagnosis of coronary artery disease was evaluated and significant difference between visual and semi quantitative analysis and statistically significant correlation between semi quantitative values and percentage of coranary artery stenosis was inquired.
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Key Findings & Data:Materials and Methods: 90 patients who were applied both selective coronary angiography and Tc-99m MIBI myocard perfusion SPECT were included into study.
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Conclusion & Impact:Conclusion: It is concluded that Tc-99m MIBI myocard perfusion SPECT imaging has high sensitivity and specificity in the diagnosis of coronary artery disease and there is no significant difference between visual and semi quantitative analysis but there is statistically significant correlation between semi quantitative values and percentage of coronary artery stenosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Geriyedönük çalışma · Teknesyum Tc 99m sestamibi · Koroner hastalık

Abstract

Purpose: The importance of Tc-99m MIBI myocard perfusion SPECT imaging in the diagnosis of coronary artery disease was evaluated and significant difference between visual and semi quantitative analysis and statistically significant correlation between semi quantitative values and percentage of coranary artery stenosis was inquired. Materials and Methods: 90 patients who were applied both selective coronary angiography and Tc-99m MIBI myocard perfusion SPECT were included into study. SPECT imaging were assesed by visual and semi quantitative analysis. The sensitivity and specificity of SPECT were defined by assuming selective coronary angiography as"gold standard".It was compared that SPECT analysis methods each other and percentage of stenosis determined by selective coronary angiography and semi quantitative values. Results: There was no significant difference between visual and semi quantitative analysis in the diagnosis of coronary artery disease but there was statistically significant correlation between semi quantitative values and percentage of coronary artery stenosis. Conclusion: It is concluded that Tc-99m MIBI myocard perfusion SPECT imaging has high sensitivity and specificity in the diagnosis of coronary artery disease and there is no significant difference between visual and semi quantitative analysis but there is statistically significant correlation between semi quantitative values and percentage of coronary artery stenosis.

Özet

Amaç: Bu çalışmada Tc-99m MIBI myokard Pefüzyon SPECT görüntüleme metodunun koroner arter hastalığı tamsındaki değeri retrospektif olarak araştırıldı. Görsel ve yarı sayısal analiz teknikleri kendi arasında karşılaştırıldı. Yarı sayısal analiz skorları ile koroner arter stenoz yüzdeleri arasında anlamlı bir korelasyon olup almadığına bakıldı. Gereç ve Yöntem: Hem selektif koroner anjiyorafi ve hem de Tc-99m MIBI myokard perfüzyon SPECT görüntülemesi yapılmış 90 olgu saptandı. Olguların SPECT görüntüleri görsel ve yarı sayısal analiz yöntemleri ile değerlendirildi. Koroner anjiografi sonuçları "altın standart" olarak kabul edilerek Tc-99m MIBI myokard perfüzyon SPECT görüntülemesinin duyarlılık ve özgüllüğü saptandı. Görsel ve yarı sayısal analiz yöntemleri kendi arasında ve yarı sayısal analiz yöntemi ile elde edilen skorlar, koroner anjiografide saptanan stenoz yüzdeleri ile karşılaştırıldı. Bulgular: Görsel ve yarı sayısal değerlendirme yöntemleri arasında koroner arter hastalığı tanısında istatiksel bir fark bulunamazken, yarı sayısal analiz yöntemleri ile elde edilen skorlar ile koroner anjiografide saptanan stenoz yüzdeleri arasında istatiksel olarak korelasyon olduğu bulundu. Sonuç: Yaptığımız bu çalışmada Tc-99m MIBI myokard perfüzyon SPECT görüntülemesinin koroner arter hastalığı tanısında yüksek duyarlılık ve özgüllüğe sahip olduğu, görsel ve yarı sayısal analizleri arasında belirgin bir fark olmadığı ve yarı sayısal analiz skorları ile koroner arter stenoz yüzdeleri arasında istatiksel olarak anlamlı bir korelasyon olduğu gösterilmiştir.

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Cite This Article

SERDENGEÇTİ, M., ENTOK, E., SARI, O., ILGAN, S., BAYHAN, H. (2005). The evaluation of Tc-99m MIBI myocardial perfusion scintigraphy by visual and semi quantitative analysis methods in the diagnosis of coronary artery disease. Tıp Araştırmaları Dergisi, Cilt: 3 - Sayı: 2, 1–7. https://ajindex.com/articles/361868

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