Journals / Tıp Araştırmaları Dergisi / 2014 / Cilt: 12 - Sayı: 2

Gestational Trophoblastic Disease: Tertiary Center Experience

Gestasyonel Trofoblastik Hastalık: Uçüncü Basamak Deneyimi

Pages
60–62
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The incidence of gestational trophoblastic disease in our clinic was found as per 1000 deliveries and the most common complaints was vaginal bleeding.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: We aimed to investigate risk factors, diagnosis and follow up of the patients diagnosed as gestational trophoblastic disease in our clinic.
📊
Key Findings & Data:Methods: The patients diagnosed as molar pregnancy between January 2010- August 2013 reviewed and patients age, parity gravity and aborts were recorded.
💡
Conclusion & Impact:Conclusion: The incidence of gestational trophoblastic disease in our clinic was found as per 1000 deliveries and the most common complaints was vaginal bleeding.
🔬Design:Review & Systematic Survey
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: We aimed to investigate risk factors, diagnosis and follow up of the patients diagnosed as gestational trophoblastic disease in our clinic. Methods: The patients diagnosed as molar pregnancy between January 2010- August 2013 reviewed and patients age, parity gravity and aborts were recorded. The patients complaints, physical examination, ultrasonographic findings, [3 HCG and complete blood count, treatment and complications, pathology results were recorded. Results: The incidence of molar pregnancy was found as per 1000 deliveries. The mean age of the patients was 28:l:4.5 and mean gestational weak was 8:|:3.2. The most common complaints of the patients were vaginal bleeding (n=23, 57.5%), amenorrhea (n=10, 25%) and abdominal pain (n=6, 15%). [3 HCG values was found between 191 and 125200. Out of all patients, 26 (65%) had ultrasonographic signs of molar pregnancy. Pathology results revealed partial mole in 26 (%65), complete mole in 13 (%32.5) patients and choriocarcinoma in (%2.5) patients. No mortality related to disease and complications was observed. Conclusion: The incidence of gestational trophoblastic disease in our clinic was found as per 1000 deliveries and the most common complaints was vaginal bleeding.

Özet

Kliniğimizde gestasyonel trofoblastik hastalık nedeniyle tedavi edilen hastaların risk faktörleri, tanısı, yönetimini araştırmayı amaçladık. Gereç ve Yöntem: Kliniğinize Ocak 2010- Ağustos 2013 yılları arasında molar gebelik tanısı almış hastalar taranarak hastaların yaşı, gravide, parite ve abortus bilgileri kaydedildi. Hastaların şikayeti, muayene, ultrason bulguları, [3 HCG ve tam kan sayımı değerleri, hastalığın tedavisi, patoloji sonuçları, hastalarda gelişen komplikasyonlar, takipte [3 HCG değerleri kayıt edildi. Bulgular: Kliniğimizde molar gebelik hızı 1000 doğumda olarak bulundu. Hastaların ortalama yaşı 28:l:4,5 olup ortalama gestasyonel yaş 8:|:3,2 haftaydı. Hastaların en sık geliş şikâyeti vajinal kanama (n=23, %57,5), amenore (n=10,%25) karın ağrısı (n=6, %15) idi. [3 HCG değerleri 191 ile 125200 arasında değişmekteydi. Hastaların 26 (65%) sında ultrason bulgusu molar gebelik lehine yorumlanmıştı. Patoloji sonuçları 26 (%65) hastada parsiyel mol, 13 (%32.5) hastada komplet mol ve (%2.5) hastada koryokarsinom gelmiştir. Hastalık ve komplikasyonlarına ait ölüm olgusuna rastlanmamıştır. Sonuç: Kliniğimizde molar gebelik hızı 1000 doğumda olup en sık geliş şikâyeti vajinal kanamadır.

🔖

Cite This Article

KURT, R. K., HAKVERDİ, A. U., KARAPINAR, O. S., KARATEPE, A., ÖZÇİL, M. D. (2014). Gestational Trophoblastic Disease: Tertiary Center Experience. Tıp Araştırmaları Dergisi, Cilt: 12 - Sayı: 2, 60–62. https://ajindex.com/articles/361813

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Berkowitz RS, Goldstein DP. Chorionic tumors. The New England journal of medicine. 1996; 335:1740-8.
  2. Gillespie AM, Lidbury EA, Tidy JA, Hancock BW. The clinical presentation, treatment, and outcome of patients diagnosed with possible ectopic molar gestation. International journal of gynecological cancer: official journal of the International Gynecological Cancer Society. 2004; 14: 366-369.
  3. Ozalp SS, Oge T. Gestational trophoblastic diseases in Turkey. The Journal of reproductive medicine. 2013; 58: 67-71.
  4. Altieri A, Franceschi S, Ferlay J, Smith J, La Vecchia C. Epidemiology and aetiology of gestational trophoblastic diseases. The lancet oncology. 2003; 4: 670-678.
  5. Rice LW, Lage JM, Berkowitz RS, Goldstein DP, Bernstein MR. Repetitive complete and partial hydatidiform mole. Obstetrics and gynecology. 1989; 74: 217-219.
  6. Hayashi K, Bracken MB, Freeman DH, Jr., Hellenbrand K. Hydatidiform mole in the United States (1970-1977): statistical and theoretical analysis. American journal of epidemiology. 1982; 115: 67-77.
  7. Fowler DJ, Lindsay I, Seckl MJ, Sebire NJ. Routine pre-evacuation ultrasound diagnosis of hydatidiform mole: experience of more than 1000 cases from regional referral center. Ultrasound in obstetrics gynecology: the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2006; 27: 56-60. Kohorn EI. The new FIGO 2000 staging and risk factor scoring system for gestational trophoblastic disease: description and critical assessment. International journal of gynecological cancer official journal of the International Gynecological Cancer Society. 2001; 11: 73-77. Bracken MB. Incidence and aetiology of hydatidiform mole: an epidemiological review. British journal of obstetrics and gynaecology. 1987; 94: 1123-1135.
  8. Seckl MJ, Sebire NJ, Berkowitz RS. Gestational trophoblastic disease. Lancet. 2010; 376: 717- 729. Palmer JR. Advances in the epidemiology of gestational trophoblastic disease. The Journal of reproductive medicine. 1994; 39: 155-1562.
  9. Martin BH, Kim JH. Changes in gestational trophoblastic tumors over four decades. Korean experience. The Journal of reproductive medicine. 1998; 43: 60—68. Sebire NJ, Foskett M, Fisher RA, Rees H, Seckl M, Newlands E. Risk of partial and complete hydatidiform molar pregnancy in relation to maternal age. BJOG an international journal of obstetrics and gynaecology. 2002; 109: 99-102.
  10. Sebire NJ, Fisher RA, Foskett M, Rees H, Seckl MJ, Newlands ES. Risk of recurrent hydatidiform mole a