Journals / Tıp Araştırmaları Dergisi / 2009 / Cilt: 7 - Sayı: 3

Lareg sized insulinomas which are located in the pancreatic head: case report

Pankreas başına lokalize ve olagandan daha büyük insulinomalar: olgu sunumu

Pages
167–170
DOI
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⚡ TL;DR(Too Long; Didn't Read)

In this study, we aimed to present three insulinoma cases including two tumors localized to the head of pancreas and large in diameter.he pancreas, constituting 70–75% of these

📌 3 Key Takeaways

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Objective & Hypothesis:Anahtar Kelimeler: İnsülinoma, pankreas, cerrahi rezeksiyon Lareg sized insulinomas which are located in the pancreatic head: case report Abstract Insulinoma is the most common islet-cell tumor of tneoplasms (1).
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Key Findings & Data:While %80 of insulinoma are benign and %10 are malignant, %4-10 present with multiple endocrine neoplasia type I (MEN I) (2,3).
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Conclusion & Impact:In this study, we aimed to present three insulinoma cases including two tumors localized to the head of pancreas and large in diameter.he pancreas, constituting 70–75% of these
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Orta yaşlı · Erişkin · Kadın

Abstract

Anahtar Kelimeler: İnsülinoma, pankreas, cerrahi rezeksiyon Lareg sized insulinomas which are located in the pancreatic head: case report Abstract Insulinoma is the most common islet-cell tumor of tneoplasms (1). While %80 of insulinoma are benign and %10 are malignant, %4-10 present with multiple endocrine neoplasia type I (MEN I) (2,3). As most of them are smaller than 2 cm and solitary (2,4), the surgical procedures that are applied are easy and curative. The rare malignant insulinomas have tendency to have larger diameter (5). In these cases, especially in the larger and multiple insulinomas which are localized to head of pancreas, large resections might be necessary that can increase the morbidity and mortality. In this study, we aimed to present three insulinoma cases including two tumors localized to the head of pancreas and large in diameter.he pancreas, constituting 70–75% of these

Özet

İnsülinoma pankreas adacık hücre tümörlerinin %70-75 ini teşkil eder (1). İnsülinomaların %80’i benign, 10’u malign olup %4-10’u multipl endokrin neoplazi tip I (MEN I) sendromu ile birlikte görülür (2, 3). Çoğunluğu 2 cm’den küçük ve soliter olduğundan (2, 4) uygulanan cerrahi yöntemler kolay ve küratif olmaktadır. Nadir görülen malign insülinomalar daha büyük çapta olma eğilimindedirler (5). Bu olgularda, özellikle pankreas başına lokalize büyük çaplı veya multipl insülinomalarda morbidite ve mortaliteyi arrtırabilen geniş rezeksiyonlar gerekebilir. Bu çalışmada ikisi pankreas başına lokalize ve büyük çaplı üç insülinoma olgusunu sunmayı amaçladık.

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Cite This Article

ÇOBAN, S., TERZİ, A., YILDIZ, F., ÖZGÖR, D., ARA, C., YILMAZ, S., ÖZDOĞAN, M. K. (2009). Lareg sized insulinomas which are located in the pancreatic head: case report. Tıp Araştırmaları Dergisi, Cilt: 7 - Sayı: 3, 167–170. https://ajindex.com/articles/361689

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References (15)

  1. Kavlie H, White TT. Pancreatic islet beta cell tumors and hyperplasia: experience in fourteen Seattle hospitals. Ann Surg 1972;175:326–335
  2. Park BJ, Alexander HR, Libutti SK, et al. Operative management of islet-cell tumors arising in the head of the pancreas. Surgery 1998;124:1056–61
  3. Sheppard BC, Norton JA, Doppman JL, et al. Management of islet cell tumors in patients with multiple endocrine neoplasia: a prospective study. Surgery 1989; 106:1108– 17
  4. Abood GJ, Go A, Malhotra D, Shoup M. The surgical and systemic management of neuroendocrine tumors of the pancreas. Surg Clin North Am. 2009;89:249-66
  5. Ehehalt F, Saeger HD, Schmidt CM, Grützmann R. Neuroendocrine tumors of the pancreas. Oncologist. 2009;14:456-67
  6. Regitnig P, Spuller E, Denk H. Insulinoma of the pancreas with insular-ductular differentiation in its liver metastasis-- indication of a common stem-cell origin of the exocrine and endocrine components. Virchows Arch. 2001;438:624-8
  7. Grossmann M, Trautmann ME, Poertl S, Hoermann R, Berger P, Arnold R, Mann K. Alpha-subunit and human chorionic gonadotropin-beta immunoreactivity in patients with malignant endocrine gastroenteropancreatic tumours. Eur J Clin Invest. 1994;24:131-6
  8. Finlayson E, Clark OH. Surgical treatment of insulinomas. Surg Clin North Am. 2004;84:775-85
  9. Service FJ, O'Brien PC, McMahon MM, Kao PC. C-peptide during the prolonged fast in insulinoma. J Clin Endocrinol Metab. 1993;76:655-9
  10. Galiber AK, Reading CC, Charboneau JW, et al. Localization of pancreatic insulinoma: comparison of pre and intraoperative US with CT and angiography. Radiology 1988;166:405-408
  11. Angeli E, Vanzulli A, Castrucci M, Venturini M, Sironi S, Zerbi A, Di Carlo V, Pozza G, Del Maschio A. Value of abdominal sonography and MR imaging at 0.5 T in preoperative detection of pancreatic insulinoma: a comparison with dynamic CT and angiography. Abdom Imaging. 1997;22:295-303
  12. Proye C, Pattou F, Carnaille B, et al. Intraoperative insulin measurement during surgical management of insulinomas. World J Surg 1998;22:1218–24
  13. Richards ML, Gauger PG, Thompson NW, Kloos RG, Giordano TJ. Pitfalls in the surgical treatment of insulinoma. Surgery. 2002;132:1040-9
  14. Thompson GB, Service FJ, van Heerden JA, Carney JA, Charboneau JW, O'Brien PC, Grant CS. Reoperative insulinomas, 1927 to 1992: an institutional experience. Surgery. 1993;114:1196-204
  15. Simon D, Starke A, Goretzki PE, Roeher HD. Reoperative surgery for organic hype