Journals / Tıp Araştırmaları Dergisi / 2009 / Cilt: 7 - Sayı: 1

Intrauterine fetal goiter

İntrauterin fetal guatr

Pages
47–50
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the present paper, we report a case with fetal goiter and polyhydramnios whose mother had used PTU.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Thyroid gland disorders are common in reproductive period of women.
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Key Findings & Data:Hyperthyroidism is one of the most frequent maternal endocrinopathies.
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Conclusion & Impact:In the present paper, we report a case with fetal goiter and polyhydramnios whose mother had used PTU.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Thyroid gland disorders are common in reproductive period of women. Hyperthyroidism is one of the most frequent maternal endocrinopathies. Hyperthyroidism has detrimental effects on gestation process, on fetus and on neonatal conditions in postpartum period. Propylthiouracil (PTU) is preferred in pregnant women due to its low passage through placenta. However, because of its fetal hypothyroidic effects, PTU should be tailored so that to keep the serum free thyroxine at its highest-borderline level while using the drug at its lowest dosage. In the present paper, we report a case with fetal goiter and polyhydramnios whose mother had used PTU.

Özet

Üreme çağındaki kadınlarda tiroid bezi hastalıkları sık görülmektedir. Hipertiroidizm, gebelikte sıklıkla rastlanılan maternal endokrinopatilerden biridir. Hipertiroidizm gebelik seyrini, fetusu, postpartum dönemde maternal ve neonatal koşulları olumsuz etkiler. Propilthiouracil (PTU) plasentadan daha az geçtiği için gebe kadınlarda tercih edilmektedir. Ancak yüksek dozda fetal hipotiroidiye neden olacağından serum serbest tiroksin düzeyini üst sınırda tutan en düşük doz hedeflenmelidir. Bu yazıda polihidramniyosu mevcut olan ve hipertiroidik annesi PTU kullandığı için fetal guatr oluşan bir olguyu sunuyoruz.

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Cite This Article

SAK, M. E., KOPLAY, M., ÖZKUL, Ö., SAK, S., ÇAÇA, F. N. (2009). Intrauterine fetal goiter. Tıp Araştırmaları Dergisi, Cilt: 7 - Sayı: 1, 47–50. https://ajindex.com/articles/361664

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References (5)

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