Journals / Tıp Araştırmaları Dergisi / 2010 / Cilt: 8 - Sayı: 1

The serum zinc level in 0-2 year old hospitalized children with bronchopneumonia

Bronkopnömoni tanısıyla hastaneye yatırılan 0- 2 yaş arası çocuklarda serum çinko düzeyi

Pages
34–39
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This was not statistically significant. future work will be done in a larger series of patients, will ensure a more healthy results.

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Objective & Hypothesis:Aim: İn this study, we investigated relationship between bronchopneumonia and serum zinc level in 0-2 age group hospitalized children with bronchopneumonia Material and Method: The study included 0-2 years old, 27 children with bronchopneumonia were admitted to hospital can not be treated as outpatients.
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Key Findings & Data:The same age group also included in the study 15 healthy children without any disease.
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Conclusion & Impact:This was not statistically significant. future work will be done in a larger series of patients, will ensure a more healthy results.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: İn this study, we investigated relationship between bronchopneumonia and serum zinc level in 0-2 age group hospitalized children with bronchopneumonia Material and Method: The study included 0-2 years old, 27 children with bronchopneumonia were admitted to hospital can not be treated as outpatients. The same age group also included in the study 15 healthy children without any disease. In both groups, serum zinc, glucose, iron, urea, creatinine, albumin, hemogram, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) measurements and chest radiography were examined. Results : The mean age of the patient group (6.41 ± 5.6 months) and control group (6.17 ± 5.1 months) with no significant difference between the mean age was not found(p 0.05). Gender distribution of both groups were not different (p 0.05, X2 = 0.087). Of the patients, iron, total protein, albumin levels, significantly lower compared to the control group were detected. (respectively p = 0.017, p 0.001 p = 0.003). Zinc levels were lower in patients(100 ± 31.1 mg / dl). However, with the control group (125.8 ± 52.3 mg / dl) was not significant between patient groups(p 0.05). Albumin and total protein in patients with weak positive correlation between zinc levels were observed(Zinc-albumin r coefficient: 0.241, p = 0.268 for total protein and zinc-r coefficient: 0.397, p = 0.061).. However, a correlation between zinc and iron levels was observed(zinc-iron for the r coefficient: -0.065, p = 0.769). Conclusions: In this study we have put children under 2 years who had bronkopnömoni plasma zinc level, is lower than normal healthy children. This was not statistically significant. future work will be done in a larger series of patients, will ensure a more healthy results.

Özet

Amaç: Bu çalışmada bronkopnömoni teşhisiyle hastaneye yatırılan 0-2 yaş grubu çocuklarda, serum çinko düzeyi ile bronkopnömoni arasındaki ilişki araştırıldı. Materyal ve Metot: Çalışmamıza 0-2 yaş arasında, ayaktan tedavi edilemeyip servise yatırılan 27 bronkopnömoni vakası ile aynı yaş grubunda hiçbir hastalığı olmayan 15 sağlıklı çocuk dahil edildi. Her iki grupta da serum çinko, glukoz, demir, üre, kreatinin, albumin, hemogram, eritrosit sedimantasyon hızı (ESH), C-reaktif protein (CRP) ölçümleri ile akciğer grafisi incelendi. Bulgular: Hasta grubunun yaş ortalaması(6,41±5,6 ay) ile kontrol grubunun yaş ortalaması(6,17±5,1 ay) arasında anlamlı bir fark bulunmadı(p pozitif bir korelasyon gözlenirken ( çinko-albümin için r katsayısı:0,241;p=0,268 ve çinko-total protein için r katsayısı: 0,397; p=0,061);çinko-demir düzeyleri arasında bir korelasyon gözlemlenmedi (çinko-demir için r katsayısı:-0,065;p=0,769). Sonuç: Bronkopnömoni geçiren 2 yaş altı çocukların plazma çinko düzeyinin, normal sağlıklı çocuklardan daha düşük olduğunu belirledik. Bu düşüklüğün istatiksel olarak anlamlı bulunmaması nedeniyle, ilerde yapılacak çalışmaların daha geniş olgu serilerinde yapılması, daha sağlıklı sonuçlar elde edilmesini sağlayacaktır.

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Cite This Article

TANRIVERDİ, M. H., TURAN, E., KARADAĞ, A., ELEVLİ, M. (2010). The serum zinc level in 0-2 year old hospitalized children with bronchopneumonia. Tıp Araştırmaları Dergisi, Cilt: 8 - Sayı: 1, 34–39. https://ajindex.com/articles/361645

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References (15)

  1. T.C Hükümeti -UNICEF 2001 -2005 işbirliği programı. Türkiye’ de çocuk ve kadınların durumu raporu. Aralık 2003: 103 -85
  2. Toraks derneği çocukluk çağında TKP tanı ve tedavi rehberi ( 2002) www.toraks.org
  3. DSÖ: İntegrated Management of Childhood İllness ( 2003). http://www.who.int/child adolescent-health 4. Henricsaon KJ. Viral pneumonia in children. Sem Pediatr İnfect Dis J 1998; 9; 217 -33. 5. http://members.iquest.net/vepachedu/Zinc1.ht ml (2004)
  4. Sazawal S, et al. Pediatrics 1998; 102 ( 1); 1 -5
  5. Black RE; Sazawal S., Zinc and childhood infectious disease morbidity and mortality. Br J Nutr 2001 May; 85 Suppl 2: S 125 -9. 8
  6. Valle BL, Falchuk KH. The Biochemical basis of zinc physiology. Physiol. Rev. 1993; 73: 79 -118
  7. De Raeve HR, Thunnissen FB, Kaneko FT, Guo FH, Lewis M et al: Decreased Cu, Zn SOD activity in asthmatic airway epithelium correction by inhaled corticosteroid in vivo. Am J Physiol Lung Cell Mol. Physiol 1997; 272: L148 -154
  8. Hennig B, Wang Y, Ramasamy S, McClain CJ. Zinc deficiency alters barrier function of cultured porcine endothelial cells. J. Nutr. 1992; 122: 1242 -1247
  9. Henning B, Meerarani P, Ramadass P et al. Zinc Nutrition and apoptosis of vascular endothelial cells: implications in atherosclerosis. Nutrition 1999; 15: 744 -748
  10. Prasad A.S., Maile A., et al: Zinc metabolism in patients with the syndrome of iron deficiency anemia, hepatosplenomegaly, dwarfism and hypogonadism: J.Lab.Clin.Med., 61: 537 -49
  11. Oberleas D, Prasad AS. Factors affecting Zinc homeostasis. In Prasad AS (ed): Trace Elements in Human Health and Disease, (New York Academic Pres.) 1996; Vol 1: 155 -161
  12. Kılıç İ., Özalp İ., Coşkun T., Tokatlı A., Emre S., Sanal Ö., Saldamlı İ., Köksel H. 7 11 yaş okul çocuklarının serum ve lökosit çinko düzeyleri,çinko eksikliğinin tedavisnde çinko içeren ekmeğin yeri. XXXIX. Milli Pediatri Kongresi Bildiri Özetleri Kitabı. 1995, 303
  13. Melaku Umeta, Clive E West, Jemal Haidar, Paul Deurenberg, Joseph G.A.J. Hautvast (2000). Zinc supplemantation and stunted infants in Ethiopia: a randomised controlled trial, Wageningen University, Netherlends. 355: 9220 -9237
  14. W Abdullah Brooks, M Yunus, Mathuram Santosham, M A Wahed, Kamrun Nahar, Sultana Yeasmin ( 2004). Zinc for severe pneumonia in very young children: double blind placebo -controlled trial. Bangladesh, 363: 9422 -9439
  15. Saket Kumart, Shally Awasthit, Amita Jaint, R.C.Srivastava ( 2003). Blood Zin Levels in Children Hospitali