Journals / Dicle Tıp Dergisi / 2013 / Cilt: 40 - Sayı: 3

Yanık yaralarından izole edilen patojenler ve antibiyotik direnç durumları

Common pathogens isolated from burn wounds and their antibiotic resistance patterns

Pages
364–368
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

So, new strategies of infection prevention should improve as soon as possible.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Burn wound infections are the most severe cause of mortality in patients in the burn units.
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Key Findings & Data:Methods: Medical records of 151 burn patients admitted to the burn unit of Dicle University Hospital between June, 2008 and June 2010 were reviewed retrospectively.
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Conclusion & Impact:So, new strategies of infection prevention should improve as soon as possible.
🔬Design:Review & Systematic Survey
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Burn wound infections are the most severe cause of mortality in patients in the burn units. The aim of this study is to determine the bacteriological profile and their antibiotic resistance patterns in burn unit of Dicle University Hospital. Methods: Medical records of 151 burn patients admitted to the burn unit of Dicle University Hospital between June, 2008 and June 2010 were reviewed retrospectively. Results: Our study included 70.2% (n=106) male and 29.8% (n=45) female patients. The mean age of cases was 10.9±14.7 years. The rate of isolated microorganisms were 62.3% (n=94) Acinetobacter baumannii, 25.8% (n=39) Pseudomonas aeruginosa, 7.3% (n=11) Escherichia coli and 4.6% (n=7) Staphylococcus aureus. The most effective antibiotic against A. baumannii was colistin (95%) followed by levofloxacin (84%) and trimethoprimsulfamethoxazole (87%). The most effective antibiotics against P. aeruginosa were amikacin (82%), ciprofloxacin (71%) and levofloxacin (71%). The most effective antibiotics against E. coli were amikacin (91%), meropenem (73%) and imipenem (82%). Conclusion: The prevalence of burn wound infection caused by A. baumannii and multiple drug resistant A. baumannii are increasing worldwide by time. The prevalence of multiple drug resistant P. aeruginosa and E. coli are rising also. So, new strategies of infection prevention should improve as soon as possible.

Özet

Amaç: Yanık yara enfeksiyonları yanık ünitelerindeki hastaların en sık ölüm nedenleridir. Amacımız Dicle Üniversitesi Hastanesi yanık ünitesindeki bakteri profilini ve antibiyotik direnç paternlerini belirlemekti. Yöntemler: Dicle Üniversitesi Hastanesi yanık ünitesinde Haziran 2008 ve Haziran 2010 tarihleri arasında yatarak takip edilen 151 hastanın dosyaları geriye dönük olarak incelendi. Bulgular: Çalışmamız 106 (%70,2) erkek ve 45 (%29,8) kadın hastadan oluşuyordu. Olguların yaş ortalaması 10.9±14.7 yıl olarak bulundu. İzole edilen mikroorganizmalar; %62,3 (n=94) Acinetobacter baumannii, %25,8 (n=39) Pseudomonas aeruginosa, %7,3 (n=11) Escherichia coli and %4,6 (n=7) Staphylococcus aureus olarak saptandı. A. baumanniiye karşı en etkili antibiyotik kolistin idi, ikinci sırada levofloksasin (%84) ve üçüncü sırada trimethoprim-sülfametoksazol (%87) takip ediyordu. P. aeruginosaya karşı en etkili antibiyotikler; amikasin (%82), siprofloksasin (%71) ve levofloksasin (%71) idi. E. coliye karşı en etkili antibiyotikler ise amikasin (%91), meropenem (%73) ve imipenem (%82) idi. Sonuç: A. baumannii nedeniyle oluşan yanık yara enfeksiyonları ve çoklu ilaç direncine sahip A. baumanniinin yaygınlığı dünyada giderek artmaktadır. Çoklu ilaç direncine sahip P. aeruginosa ve E. coli patojenleri de artmaktadır. Bu nedenle en kısa zamanda yeni enfeksiyon önleme stratejileri geliştirilmelidir.

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Cite This Article

YOLBAŞ, İ., TEKİN, R., KELEKÇİ, S., SELÇUK, C. T., OKUR, M. H., TAN, İ., ULUCA, Ü. (2013). Yanık yaralarından izole edilen patojenler ve antibiyotik direnç durumları. Dicle Tıp Dergisi, Cilt: 40 - Sayı: 3, 364–368. https://ajindex.com/articles/348991

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