SavedAdd your journal

Journals / Van Tıp Dergisi / 2014 / Cilt: 21 - Sayı: 4

The Evaluation of Newborns with Meconium Aspiration Syndrome in Neonatal Intensive Care Unit

Yenidoğan Yoğun Bakım Ünitesinde Mekonyum Aspirasyon Sendromlu Yenidoğanların Değerlendirilmesi

Velat ŞEN
Müsemma KARABEL
Ünal ULUCA
ELİF AĞAÇAYAK
İlhan TAN
Duran KARABEL
FESİH AKTAR
İlyas YOLBAŞ
Pages
230–235
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The overall mortality was 21.7%.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Meconium aspiration syndrome (MAS) is one of the common causes of respiratory distress in term infants presenting highly variable morbidity and mortality.
📊
Key Findings & Data:A total of 106 newborns diagnosed as MAS between January 2011 and September 2013 were retrospectively evaluated.
💡
Conclusion & Impact:The overall mortality was 21.7%.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Meconium aspiration syndrome (MAS) is one of the common causes of respiratory distress in term infants presenting highly variable morbidity and mortality. The aim of this study was to evaluate the demographic data, possible risk factors, factors associated with morbidity and mortality in MAS newborns. Materials and Methods: The study was conducted at Neonatal Intensive Care Unit (NICU) of Dicle University Medical School Department of Pediatrics. A total of 106 newborns diagnosed as MAS between January 2011 and September 2013 were retrospectively evaluated. Results: MAS found to be responsible from 1.05% of NICU admissions. The study included 51 (48.1%) male and 55 (51.9%) female newborns. Of them 63 (59.4%) were term infants and 25 (23.6%) were postterm. The mean gestational age was 38.6 ± 2.4 (34- 43) weeks and the mean birth weight was 3136 ± 655 (1700-4300) gram. The mean hospitalization duration was 8.7±4.4 (range 3-27) days. The first minute APGAR score <= 3 was found in 54 (50.9%) and the fifth minute APGAR score <= 3 was found in 10 (9.43%) of newborns with MAS. The overall mortality was 21.7%. Conclusion: The first minute APGAR score <= 3 was found to be related to increased morbidity and mortality. Determination of risk factors associated with MAS is important regarding diagnosis and implementing early treatment strategies. It was tought that morbidity and mortality rates could be ameliorated by prevention of post term gestation and performing cesarian section at appropriate time.

Özet

Amaç: Mekonyum aspirasyon sendromu (MAS) term infantlarda solunum sıkıntısı nedenlerinden olup değişken morbidite ve mortalite ile seyredebilmektedir. Bu çalışmanın amacı MAS tanısı konan yenidoğanlarda demografik verileri, muhtemel risk faktörlerini ayrıca morbidite ve mortalite ile ilgili durumları değerlendirmektir. Gereç ve Yöntem: Bu çalışmamızda Dicle Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Yenidoğan Yoğun Bakım Ünitesi'nde (YYBÜ) Ocak 2011- Eylül 2013 tarihleri arasında MAS tanısı alan 106 yenidoğan retrospektif olarak değerlendirildi. Bulgular: MAS YYBÜ yatışlarının %1.05'inden sorumlu bulundu. Olgularımızın 51'i (%48.1) erkek, 55'i (%51.9) kız, 63'ü (%59.4) term, 25'i (%23.6) post-term idi. Gestasyon haftaları 38.6 ± 2.4 hafta, doğum ağırlıkları 3136 ± 655 gr bulundu. Ortalama yatış süreleri 8.7 ± 4.4 gündü. 54 (% 50.9) olgunun 1. dakika Apgar skoru <= 3 ve 10 (%9.43) olgunun 5. dakika Apgar skoru <= 3 idi. Mortalite oranı %21.7 idi. Sonuç: 1. dakika Apgar skoru <= 3 olması MAS'lı olgularda artmış morbidite ve mortalite ile ilişkili olarak bulundu. MAS ile ilişkili risk faktörlerinin tanımlanması hastalığın teşhisinde ve erken tedavi stratejilerinin geliştirilmesinde önemlidir. Post-term gebeliklerden korunmakla ve fetal distres durumunda sezeryan doğumların uygun zamanda yapılması ile morbidite ve mortalite oranlarının iyileştirilmesinin mümkün olacağı düşünüldü.

🔖

Cite This Article

ŞEN, V., KARABEL, M., ULUCA, Ü., AĞAÇAYAK, E., TAN, İ., KARABEL, D., AKTAR, F., YOLBAŞ, İ. (2014). The Evaluation of Newborns with Meconium Aspiration Syndrome in Neonatal Intensive Care Unit. Van Tıp Dergisi, Cilt: 21 - Sayı: 4, 230–235. https://ajindex.com/articles/334103

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Hermansen CK. Lorah Respiratory Distress in the Newborn. Am Fam Physician 2007; 76(7):987-994. Bhutani VK. Developing a systems approach to Prevent Meconium Aspiration Syndrome: lessons learned from Multinational studies. J Perinatol 2008; 28(3):30-35. Keenan W. Recommendations for Management of the Child Born Through Meconium-Stained Amniotic Fluid. Pediatrics 2004; 113(1):133- 134. Bhatia BD, Gupta V, Dey PK. Meconium aspiration syndrome: current consepts. Indian J Matern Child Health 1996; 7(1):1-7. Wiswell TE. Handling the meconium-stained infant, Seminars in Neonatology 2001; 6(3):225- 231. Whitfield JM, Charsha DS, Chiruvolu A. Prevention of meconium aspiration syndrome: an update and the Baylor experience, Proceedings (Baylor University. Medical Center) 2009; 22(2):128-131.
  2. Sriram S, Wall SN, Khoshnood B, Singht JK, Hsieh HL, Lee KS. Racial disparity in meconium stained amniotic fluid and meconium aspiration syndrome in the United States, 1989- 2000. Obstet Gynecol 2003; 102(6):1262-1268.
  3. Karatekin G, Kesim M, Nuhoğlu A. Risk factors for meconium aspiration syndrome. International Journal of Gynecology Obstetrics 1999; 65(3):295-297.
  4. Dargaville P, Copnell B. The Epidemiology of Meconium Aspiration Syndrome: Incidence, Risk Factors, Therapies and Outcome. Pediatrics 2006; 117(5):1712-1721.
  5. May Beligere N, Rao R. Neurodevelopmental outcome of infants with meconium aspiration syndrome: report of a study and literature review. J Perinatol 2008; 28(3):93-101.
  6. Singh BS, Clark RH, Powers RJ, Spitzer AR. Meconium Aspiration Syndrome A signifi cant problem remains in the NICU: outcomes and treatment patterns in term neonates for intensive care Admitted During the ten-year period. J Perinatol 2009; 29(7):497-503.
  7. Carbine D, Serwint J. Meconium aspiration. Pediatr Rev 2008; 29(6):212-213.
  8. Velaphi S, Kwawegen AV. Meconium Aspiration Syndrome Requiring assisted ventilation: perspective in a setting with limited resources. J Perinatol 2008; 28(3):36-42. Fanaroff AA. Meconium aspiration syndrome: historical aspects. J Perinatol 2008; 28(3):3-7.
  9. Sedaghatian MR, Othman L, Hossain MM, Vidyasagar D. Risk of meconium-stained amniotic fluid in different ethnic groups. Journal of Perinatology 2000; 20(4):257-261.
  10. Blackwell SC, Moldenhauer J, Hassan SS, Redman ME, Refuerzo JS, Berry SM, et al. Meconium aspiration syndrome in term neonates with normal acid-base status at delivery: is it different? Am J Obstet Gynecol 2001; 184(7):1422-1426.
  11. Xu H, Mas-Calvet M, Wei SQ, Luo