Journals / Kulak Burun Boğaz ve Baş Boyun Cerrahisi / 1998 / Cilt: 6 - Sayı: 3

Basaloid-squamous cell carcinomas at larynx

Larinks bazaloid-skuamöz hücreli karsinomu

Pages
161–166
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The histologic feature and prognostic factors of 6 Basaloid-Squmous Cell Carcinoma were discussed.

📌 3 Key Takeaways

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Objective & Hypothesis:Six Basaloid-Squamous Cell Carcinoma, out of 44 laryngectomy specimens, evaluated at Department of Pathology Ankara Numune Hospital have been detected.
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Key Findings & Data:The patients were male, between 41-65 years old and the localization was supraglottic.
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Conclusion & Impact:The histologic feature and prognostic factors of 6 Basaloid-Squmous Cell Carcinoma were discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Six Basaloid-Squamous Cell Carcinoma, out of 44 laryngectomy specimens, evaluated at Department of Pathology Ankara Numune Hospital have been detected. The patients were male, between 41-65 years old and the localization was supraglottic. The size of tumor ranged between 2-4 cm. In diameter. Lymph node metastasis was noted in 2 cases. In 4 cases mitotic activity ranged between 11-15 in 10 HPF and lymhoplasmocytic infiltration was found in varying degrees in almost all cases. Immunhistochemically anti S-100 protein positive Langerhans cells were detected in 3 cases. Positivity with p53 antibody was noted in 2 cases. The histologic feature and prognostic factors of 6 Basaloid-Squmous Cell Carcinoma were discussed.

Özet

Ankara Numune Hastanesi Patoloji Bölümünde 1994-1996 yılları arasında incelenen 44 larenjektomi materyalinin 6'sında bazaloid-skuamöz hücreli karsinoma saptandı. 41-65 yaşları arasındaki 6 erkek hastanın dördünde tümör supraglottik bölgede idi. Tümör çaplan 2-4 cm boyutlarında olup, iki olguda lenf nodu metastazı gözlendi. Olguların dördünde 10 büyük büyütme alanında 11-15 arası mitotik aktivite ve tüm olgularda değişen derecelerde lenfoplazmositer iltihabı hücre infiltrasyonu bulundu. İmmünhistokimyasal olarak S-100 ile üç olguda Langerhans hücreleri saptandı. p53 pozitifliği iki olguda dikkat çekici idi. Altı bazaloid-skuamöz hücreli karsinoma olgusu prognostik faktörlerle birlikte tartışıldı.

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Cite This Article

ALBAYRAK, L., GÜNÇE, S. (1998). Basaloid-squamous cell carcinomas at larynx. Kulak Burun Boğaz ve Baş Boyun Cerrahisi, Cilt: 6 - Sayı: 3, 161–166. https://ajindex.com/articles/346904