Journals / Kulak Burun Boğaz ve Baş Boyun Cerrahisi / 2019 / Cilt: 27 - Sayı: 3

The Value of Inflammatory Parameters in the Differantial Diagnosis of “Benign” and “Malignant” Lesions in Parotid Gland Tumors

Parotis Bezi Tümörlerinde “Benign” ve “Malign” Ayırıcı Tanısında İnflamatuar Parametrelerin Değeri

Pages
131–136
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These parameters can be easily calculated from routine routine hemogram analysis, and cheap and fast results can be obtained with this method.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The diagnosis of benign or malignant parotid gland masses is based on physical examination, radiological examination or interventional methods.
📊
Key Findings & Data:Material and Methods: Between November 2016 and May 2019, 95 patients operated for parotid gland tumors were included in the study.
💡
Conclusion & Impact:These parameters can be easily calculated from routine routine hemogram analysis, and cheap and fast results can be obtained with this method.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The diagnosis of benign or malignant parotid gland masses is based on physical examination, radiological examination or interventional methods. In our study, it was calculated from the parameters measured in routine blood tests; neutrophil/lymphocyte ratio (NLO), platelet/lymphocyte ratio (PLO), neutrophil count, lymphocyte count, platelet count, erythrocyte distribution width, and mean corpuscular volume and was found that they had importance in the differential diagnosis of benign-malignant masses. Material and Methods: Between November 2016 and May 2019, 95 patients operated for parotid gland tumors were included in the study. The data of the patients were analyzed retrospectively; age, sex, postoperative histopathological results and hematological parameters were recorded. Histopathological results were divided into two groups as benign and malignant. Data recorded between the two groups were compared. Results: The mean neutrophils and lymphocytes were significantly higher in malignant tumors compared to benign tumors (p=0.011 and p=0.040, respectively). The mean NLR value was 2.68±0.99 in malignant tumors and 1.84±0.95 in benign tumors, and was statistically significant (p<0,000). The mean PLO value was 153.44±81.21 in malignant tumors and 114.26±59.27 in benign tumors, and a statistically significant difference was found (p=0.016). Conclusion: NLR and PLO values can be used to differentiate benign and malignant parotid gland tumors. These parameters can be easily calculated from routine routine hemogram analysis, and cheap and fast results can be obtained with this method.

Özet

Amaç: Parotis bezi kitlelerinde benign veya malign ön tanısının konulması; fizik muayene, radyolojiktetkik veya girişimsel yöntemlerle olmaktadır. Çalışmamızda, hastaların rutin kan tetkiklerindebakılan parametrelerden hesaplanan; nötrofil/lenfosit oranı (NLO), platelet/lenfosit oranı (PLO), nötrofilsayısı, lenfosit sayısı, platelet sayısı, eritrosit dağılım genişliği ve ortalama korpuskuler volüm ileparotis kitlelerinin benign-malign ayırıcı tanısında önemini değerlendirmeyi amaçladık. Gereç ve Yöntemler:Çalışmaya, Kasım 2016-Mayıs 2019 tarihleri arasında parotis bezinde tümör nedeni ile opereedilmiş 95 hasta dâhil edildi. Hastaların verileri retrospektif olarak incelenerek; yaş, cinsiyet, postoperatif,histopatolojik sonuçlar ve hematolojik parametreler kaydedildi. Histopatolojik sonuçlar benign vemalign olarak 2 gruba ayrıldı. Her 2 grup arasında kaydedilen veriler karşılaştırıldı. Bulgular: Maligntümörlerde NLO ortalamaları benign tümörlere göre anlamlı olarak yüksek bulundu (sırasıyla p=0,011;p=0,040). Malign tümörlerde NLO ortalama değeri 2,68±0,99, benign tümörlerde 1,84±0,95 olarak hesaplandıve istatistiksel olarak anlamlı derecede yüksekdi (p<0,000). PLO ortalama değeri malign tümörlerde153,44±81,21, benign tümörlerde 114,26±59,27 olarak hesaplandı ve istatistiksel olarak anlamlıfarklılık bulundu (p=0,016). Sonuç: Parotis bezi tümörlerinin benign-malign ayrımında NLO ve PLOdeğerleri kullanılabilir. Bu parametreler rutin bakılan hemogram tahlilinden kolayca hesaplanabilen,ucuz, hızlı sonuç veren bir yöntemdir.

🔖

Cite This Article

ÖZDEMİR, D., BİRİNCİ, M., BEDİR, A., MEHEL, D. M., BAKIRTAŞ, M., ÖZGÜR, A. (2019). The Value of Inflammatory Parameters in the Differantial Diagnosis of “Benign” and “Malignant” Lesions in Parotid Gland Tumors. Kulak Burun Boğaz ve Baş Boyun Cerrahisi, Cilt: 27 - Sayı: 3, 131–136. https://ajindex.com/articles/346758

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Damar M, Dinç AE, Erdem D, Aydil U, Kizil Y, Eravcı FC, et al. Pretreatment neutrophil-lymphocyte ratio in salivary gland tumors is associated with malignancy. Otolaryngol Head Neck Surg. 2016;155(6):988-96. [Crossref] [PubMed] 2. Garrett SL, Trott K, Sebastiano C, Wolf MJ, Rao NK, Curry JM, et al. Sensitivity of fineneedle aspiration and imaging modalities in the diagnosis of low-grade mucoepidermoid carcinoma of the parotid gland. Ann Otol Rhinol Laryngol. 2019;128(8):755-9. [Crossref] [PubMed] 3. Berge T, Söderström N. Fine needle cytologic biopsy in diseases of the salivary glands. Acta Pathologica Microbiologica Scandinavica. 1963;58(1):1-9. [Crossref] [PubMed] 4. Oka K, Chikamatsu K, Eura M, Katsura F, Yumoto E, Tokunaga H. [Clinical significance of fine-needle aspiration biopsy in major salivary gland tumors]. Nippon Jibiinkoka Gakkai Kaiho. 2002;105(11):1109-15. [Crossref] [PubMed] 5. Sismanis A, Merriam JM, Kline TS, Davis RK, Shapshy SM, Strong MS. Diagnosis of salivary gland tumors by fine needle aspiration biopsy. Head Neck Surg. 1981;3(6):482-9. [Crossref] [PubMed] 6. Deveci İ, Sürmeli M. Correlation of systemic immune-inflammation index and neutrophilto- lymphocyte ratio with histopathological findings in patients with tongue cancer. The Medical Journal of Haydarpaşa Numune Training and Research Hospital. 2018;58(3): 122-7. [Crossref] 7. Quer M, Vander Poorten V, Takes RP, Silver CE, Boedeker CC, de Bree R, et al. Surgical options in benign parotid tumors: a proposal for classification. Eur Arch Otorhinolaryngol. 2017;274(11):3825-36. [Crossref] [PubMed] 8. Chen L, Zhang G, Zhang Z, Wang Y, Hu L, Wu J. Neutrophil-to-lymphocyte ratio predicts diagnosis and prognosis of idiopathic sudden sensorineural hearing loss: a systematic review and meta-analysis. Medicine (Baltimore). 2018;97(38):e12492. [Crossref] [PubMed] [PMC] 9. Takenaka Y, Oya R, Kitamiura T, Ashida N, Shimizu K, Takemura K, et al. Prognostic role of neutrophil to lymphocyte ratio in head and neck cancer: a meta analysis. Head Neck. 2018;40(3):647-55. [Crossref] [PubMed] 10. Mascarella MA, Mannard E, Silva SD, Zeitoni A. Neutrophil to lymphocyte ratio in head and neck cancer prognosis: a systematic review and meta analysis. Head Neck. 2018;40(5): 1091-100. [Crossref] [PubMed] 11. Wang Y, Wang P, Andrukhov O, Wang T, Song S, Yan C, et al. Meta analysis of the prognostic value of the neutrophil to lymphocyte ratio in oral squamous cell carcinoma. J Oral Pathol Med. 2018;4