THE EFFECT OF CHRONIC OTITIS MEDIA ON HEMATOLOGICAL PARAMETERS

Objective & Hypothesis:Aim: This study aims to evaluate the relationship between the pathological conditions in the middle ear and hematological parameters of patients who underwent surgery for chronic otitis media.

📊

Key Findings & Data:Material and Methods: In the study, 82 patients and 20 healthy control groups who underwent chronic otitis surgery between January 2017 and December 2020 were retrospectively reviewed.

💡

Conclusion & Impact:However, these effects do not show specific differences for COM with cholesteatoma, active COM, and inactive COM groups

🔬Design:Review & Systematic Survey

📍Scope:2017 Verileri

⚙️Variables:Domain Parameters

Abstract

Aim: This study aims to evaluate the relationship between the pathological conditions in the middle ear and hematological parameters of patients who underwent surgery for chronic otitis media. Material and Methods: In the study, 82 patients and 20 healthy control groups who underwent chronic otitis surgery between January 2017 and December 2020 were retrospectively reviewed. The patients were divided into 3 groups according to their intraoperative findings: Chronic otitis media (COM) with cholesteatoma, active COM and inactive COM. Three groups and control groups were compared in terms of hematological parameters. Results: It was observed that 23 of the patients had COM with cholesteatoma, 34 had active COM, and 25 had inactive COM. Red cell distribution with (RDW) and platelet crit (PCT) values were statistically significantly different in COM patients compared to the control group. (p <0.05). Mean platelet volume (MPV) was statistically significantly lower in the inactive COM group compared to the other groups (p <0.05). Conclusion: Chronic otitis media causes an increase in RDW values and a decrease in PCT values. However, these effects do not show specific differences for COM with cholesteatoma, active COM, and inactive COM groups

Özet

Amaç: Bu çalışmanın amacı kronik otit cerrahisi yapılan hastalarda orta kulaktaki patolojik durumların hematolojik parametrelerleilişkisini incelemektir.Gereç ve Yöntemler: Çalışmada Ocak 2017- Aralık 2020 tarihleri arasında kronik otit cerrahisi yapılan 82 hasta ve 20 sağlıklı kontrolgrubu retrospektif olarak incelendi. Hastalar intraoperatif bulgularına göre kolesteatomalı kronik otitis media (KOM), aktif KOM ve inaktifKOM olmak üzere 3 gruba ayrıldı. Hematolojik parametreler açısından 3 grup ve kontrol grubu karşılaştırıldı.Bulgular: Hastaların 23"ünün kolesteatomalı KOM, 34"ünün aktif KOM ve 25"inin inaktif KOM olduğu görüldü. Red cell distributionwith (RDW) ve platelet crit (PCT) değerleri KOM hastalarında kontrol grubuna göre istatistiksel olarak anlamlı düzeyde farklıydı. (p<0.05).Mean platelet volüm (MPV) inaktif KOM grubunda diğer gruplara göre istatistiksel olarak anlamlı düzeyde daha düşüktü(p<0.05).Sonuç: Kronik otit RDW değerlerinde artışa ve PCT değerlerinde düşüşe neden olmaktadır. Ancak bu etkiler kolesteatomalı KOM, aktifKOM ve inaktif KOM gruplarına spesifik farklılıklar göstermemektedir.

🔖

Cite This Article

CEYLAN, S. M., DÜNDAR, T. A., BEYAZGÜN, V., PALAOĞLU, İ. (2021). THE EFFECT OF CHRONIC OTITIS MEDIA ON HEMATOLOGICAL PARAMETERS. KBB-Forum, Cilt: 20 - Sayı: 2, 156–162. https://ajindex.com/articles/343994

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (9)

Wallis S, Atkinson H, Coatesworth AP. Chronic otitis media. Postgrad Med. 2015;127:391-395
Kılıçkaya MM, Aynali G, Tuz M, Bagcı O. Is There A Systemıc Inflammatory Effect of Cholesteatoma? Int Arch Otorhinolaryngol. 2017;21:42-45
Eryilmaz MA, Derin S. Mean Platelet Volume as a Potential Predictor of Cholesteatoma in Children. J Craniofac Surg. 2016;27:e575-578
Louw L. Acquired cholesteatoma: summary of the cascade of molecular events. J Laryngol Otol. 2013;127:542?549
Li N, Qin ZB. Inflammation-induced miR-802 promotes cell proliferation in cholesteatoma. Biotechnol Lett. 2014;36:1753-1759 6. Si Y, Chen YB, Chen SJ, Zheng YQ, Liu X, Liu Y, Jiang HL, Xu G, Li ZH, Huang QH, Xiong H, Zhang ZG et al. TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction. Sci Rep. 2015;5:16683 7. Masanta WO, Hinz R, Zautner AE. Infectious causes of cholesteatoma and treatment of infected ossicles prior to reimplantation by hydrostatic high-pressure inactivation. Biomed Res Int. 2015;2015:761259 8. Manolis EN, Filippou DK, Tsoumakas C, Diomidous M, Cunningham MJ, Katostaras T, Weber AL, Eavey RD. Radiologic evaluation of the ear anatomy in pediatric cholesteatoma. J Craniofac Surg 2009;20:807-810 9. Baysal E, Erkutlu I, Mete A, Alptekin M, Oz A, Karataş ZA, Celenk F, Mumbuc S, Kanlikama M. Complications and treatment of chronic otitis media. J Craniofac Surg 2013;24:464-467
Korniluk A, Koper-Lenkiewicz OM, Kaminska J, Kemona H, Dymicka-Piekarska V. Mean Platelet Volume (MPV): New Perspectives for an Old Marker in the Course and Prognosis of Inflammatory Conditions. Mediators Inflamm. 2019;2019:9213074
Somuk BT, Soyalıc H, Koc S, Gurbuzler L, Dogru S, Eyibilen A. Mean platelet volume as an inflammatory marker of chronic otitis media with effusion. International Journal of Pediatric Otorhinolaryngology 2014;78:1958-1960 12. Zagólski O, Strek P, Jurczak W, Gorzedowski P. Peripheral blood cell count and inflammation-based markers in chronic rhinosinusitis. HNO. 2018;66:605-612
Yukkaldıran A, Erdoğan O, Kaplama ME. Neutrophillymphocyte and platelet-lymphocyte ratios in otitis media with effusion in children: Diagnostic role and audiologic correlations. Int J Clin Pract. 2020;30:e13805
Elbistanli MS, Koçak HE, Acipayam H, Yiğider AP, Keskin M, Kayhan FT. The Predictive Value of NeutrophilLymphocyte and Platelet-Lymphocyte Ratio for the Effusion Viscosity in Otitis Media With Chronic Effusion