AI Summary & Key Takeaways
AI InsightOf the patients in the advanced stage, three had extracapsular invasion, 12 had perineural invasion, and four had vascular invasion.Conclusion: According to our study findings, the prevalence of prognostic factors including perineural, vascular, and extracapsular invasions increases as the cancer stage advances.
📌 3 Key Takeaways
Abstract
Objectives: This study aims to evaluate the correlation between staging and presence of perineural, vascular, and extracapsular invasions which are prognostic factors in oral cavity squamous cell cancers.Patients and Methods: The study included 62 patients (36 males, 26 females; mean age 63.8±14.6 years; range 28 to 89 years) who were operated due to oral cavity squamous cell carcinoma between February 2002 and April 2013 in Başkent University Adana Dr. Turgut Noyan Application and Research Center. For treatment, the patients were performed surgery and some patients were performed radiotherapy and chemotherapy in addition to surgery.Results: Of the patients, 40 were in the early stage (stage 1 and 2) and 22 were in the advanced stage (stage 3 and 4). Of the patients in the early stage, three had perineural invasion and one had vascular invasion. Of the patients in the advanced stage, three had extracapsular invasion, 12 had perineural invasion, and four had vascular invasion.Conclusion: According to our study findings, the prevalence of prognostic factors including perineural, vascular, and extracapsular invasions increases as the cancer stage advances.
Özet
Amaç: Bu çalışmada oral kavite skuamöz hücreli kanserlerinde prognostik faktör olan evreleme ile perinöral, vasküler ve ekstrakapsüler invazyon varlığının ilişkisi değerlendirildi.Hastalar ve Yöntemler: Çalışmaya Başkent Üniversitesi Adana Dr. Turgut Noyan Uygulama ve Araştırma Merkezi Kulak Burun Boğaz Kliniği'nde Şubat 2002 - Nisan 2013 tarihleri arasında oral kavite skuamöz hücreli karsinom nedeniyle ameliyat edilen 62 hasta (36 erkek, 26 kadın ort. yaş 63.8±14.6 yıl; dağılım 28-89 yıl) dahil edildi. Hastaların verileri retrospektif olarak değerlendirildi. Hastalara tedavi için cerrahi ve bir kısım hastaya da cerrahiye ek olarak radyoterapi ve kemoterapi uygulandı.Bulgular: Hastaların 40'ı erken evrede (evre 1 ve 2), 22'si ileri evrede idi (evre 3 ve 4). Erken evrede olan hastaların üçünde perinöral invazyon, birinde vasküler invazyon vardı. İleri evrede olan hastaların üçünde ekstrakapsüler invazyon, 12'sinde perinöral invazyon, dördünde de vasküler invazyon vardı.Sonuç: Çalışma bulgularımıza göre, kanser evresi ilerledikçe perinöral, vasküler ve ekstrakapsüler invazyon gibi prognostik faktörlerin görülme sıklığı artmaktadır.