Journals / MN Oftalmoloji / 2021 / Cilt: 28 - Sayı: 3

Alterations in the Retinal Layers Measurements During Silicone Tamponade and After Silicone Removal in Eyes Undergone for Rhegmatogenous Retinal Detachment with Macular Involvement

Silikon Tamponadı Kullanılan Maküla Tutulumlu Regmatojen Retina Dekolmanlı Gözlerde Silikon Tamponadı Süresince ve Silikon Alımı Sonrası Retina Katmanlarındaki Değişiklikler

Pages
140–147
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Inner retinal layers and ganglion cell layer decreased in 6 months after pars plana vitrectomy and silicone oil injection in all retinal subfield area except for central fovea, based on these findings, imaging of ganglion cell layer, inner plexiform layer and inner retinal layer in silicone oil-treated eyes may provide an estimated time of silicone oil removal period.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To analyze the retinal layers by optical coherence tomography after silicone oil tamponade placed and removed in eyes with macula involved rhegmatogenous retinal detachment.
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Key Findings & Data:Material and Method: In this prospective-observational study, 42 eyes of 42 patients who received silicone oil (5000 centistokes) tamponade for macula-off rhegmatogenous retinal detachment were included.
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Conclusion & Impact:Conclusion: Inner retinal layers and ganglion cell layer decreased in 6 months after pars plana vitrectomy and silicone oil injection in all retinal subfield area except for central fovea, based on these findings, imaging of ganglion cell layer, inner plexiform layer and inner retinal layer in silicone oil-treated eyes may provide an estimated time of silicone oil removal period.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To analyze the retinal layers by optical coherence tomography after silicone oil tamponade placed and removed in eyes with macula involved rhegmatogenous retinal detachment. Material and Method: In this prospective-observational study, 42 eyes of 42 patients who received silicone oil (5000 centistokes) tamponade for macula-off rhegmatogenous retinal detachment were included. Retinal layer measurements were obtained at $1^{st} month, $3^{rd} month and $6^{th} month after pars plana vitrectomy and silicone oil injection and at $1^{st}month, $3^{rd} month and $6^{th} month after silicone oil removal. Retinal layers were measured by spectral domain optical coherence tomography in the 5 inner subfields area of the early treatment of diabetic retinopathy study (ETDRS). Results: Participants with a mean follow-up of 13.61±4.63 months (range, 9-18 months). The mean age was 60.33±11.15 years (range, 37-83 years). Mean duration of silicone oil tamponade was 6.38±1.12 months (range 3-9 months). Mean duration of macula off status was 12.85±10.25 days (range, 1-30 days). Thinning of retinal thickness up to 6 months following pars plana vitrectomy in ganglion cell layer, inner plexiform layer and inner retinal layer, and subsequent removal of silicone oil, this retinal layers recovered on its reinstate in all areas of the ETDRS except for central fovea (p<0.05). There was negative correlation between silicone oil removal time and central outer plexiform layer (r=-0.439, p=0.046), superior inner plexiform layer (r=-0.545, p=0.011), inferior retinal nerve fiber layer (r=-0.479, p= 0.028), temporal retinal nerve fiber layer (r=-0.532, p=0.013). Best corrected visual acuity increased from baseline 1.81±0.33 to final 0.91±0.51 logarithm of the minimum angle of resolution (logMAR) (p=0.001). Conclusion: Inner retinal layers and ganglion cell layer decreased in 6 months after pars plana vitrectomy and silicone oil injection in all retinal subfield area except for central fovea, based on these findings, imaging of ganglion cell layer, inner plexiform layer and inner retinal layer in silicone oil-treated eyes may provide an estimated time of silicone oil removal period.

Özet

Amaç: Maküla tutulumu olan regmatojen retina dekolmanlı gözlerde silikon tamponadı süresince ve silikon tamponadı alımı sonrası optik koherans tomografi ile retina katmanlarını analiz etmek. Gereç ve Yöntem: Bu prospektif gözlemsel çalışmada, silikon tamponadı (5000 centistokes) kullanılan maküla tutulumlu regmatojen retina dekolmanlı 42 hastanın 42 gözü dahil edildi. Retina katmanlarının analizi silikon tamponadı süresince ve silikon tamponadı alımı sonrası sırasıyla 1., 3. ve 6. ayda yapıldı. Retinal katmanlar, Erken Diyabetik Retinopati Çalışması’nın 5 alt alanına ayrılarak, spektral domain optik koherans tomografi ile değerlendirildi. Bulgular: Ortalama yaş 60,33±11,15 yıl (aralık, 37-83 yıl) olup, maküla tutulumu olan regmatojen retina dekolmanlı hastaların tümünde 6 ay süreyle silikon tamponadı kullanıldı. Ortalama maküla tutulum süresi 12,85±10,25 gündü (aralık, 1-30 gün). Göz içinde silikon tamponadı süresince (6 ay), gangliyon hücre tabakasında, iç pleksiform tabaka ve iç retina tabakalarında anlamlı incelme gözlendi (p<0,05) ve daha sonra silikon alınmasıyla, santral fovea alanı hariç bu retina katmanlarında tüm ETDRS bölgelerinde tekrar eski haline geldiği gözlemlendi (p<0,05). Silikon tamponadınun göz içindeki tamponad süresi ile santral dış pleksiform tabaka (r=-0,439, p= 0,046), üst iç pleksiform tabaka (r= -0,545, p= 0,011), alt retina sinir lifi tabakası (r= -0,479, p= 0,028) ve temporal retina sinir lifi tabakası (r=-0,532, p= 0,013) arasında negatif korelasyon saptandı. En iyi düzeltilmiş görme keskinliği, minimum çözünürlük açısının logaritması olarak (logMAR) regmatojen retina dekolmanlı başlangıcı 1,81±0,33'ten silikon tamponadı alımı sonrası 6. ayda 0,91±0,51 yükseldi (p=0,001). Sonuç: İç retina katmanları ve ganglion hücre tabakası, santral fovea hariç tüm retina bölgelerinde silikon tamponadı konulduktan sonra 6. ayda azaldı. Bu bulgulara dayanarak, silikon tamponadı ile tedavi edilen gözlerde gangliyon hücre tabakasında iç pleksiform tabaka ve iç retina tabakaları görüntülemesi, silikon tamponadı için tahmini bir alım süresi sağlayabilir.

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Cite This Article

KARASU, B. (2021). Alterations in the Retinal Layers Measurements During Silicone Tamponade and After Silicone Removal in Eyes Undergone for Rhegmatogenous Retinal Detachment with Macular Involvement. MN Oftalmoloji, Cilt: 28 - Sayı: 3, 140–147. https://ajindex.com/articles/340926

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