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Journals / Records of Natural Products / 2020 / Cilt: 14 - Sayı: 2

Phytochemical Investigation of Endemic Sideritis cypria Post

Duygu YİĞİT HANOĞLU
Azmi HANOĞLU
Hasan YUSUFOĞLU
Betül DEMİRCİ
Kemal Hüsnü Can BAŞER
İhsan ÇALIŞ
Dudu ÖZKUM YAVUZ
Pages
105–115
DOI
—
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In addition, major compounds of the essential oil were determined as -pinene (14.73±0.15%), -pinene (16.60±0.20%), -phellandrene (17.83±0.23%) and epi-cubebol (7.70±0.20%), respectively.

📌 3 Key Takeaways

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Objective & Hypothesis:Non-polar and polar compounds were isolated from the leaves and chemical composition of the essential oil from aerial parts of Sideritis cypria endemic in Northern Cyprus was also determined.
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Key Findings & Data:The structures of all the isolated compounds were elucidated by means of spectroscopic (UV, NMR: 1D and 2D-NMR: 1H, 13C, COSY, HSQC, HMBC) methods and comparison with literature data.
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Conclusion & Impact:In addition, major compounds of the essential oil were determined as -pinene (14.73±0.15%), -pinene (16.60±0.20%), -phellandrene (17.83±0.23%) and epi-cubebol (7.70±0.20%), respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Non-polar and polar compounds were isolated from the leaves and chemical composition of the essential oil from aerial parts of Sideritis cypria endemic in Northern Cyprus was also determined. The structures of all the isolated compounds were elucidated by means of spectroscopic (UV, NMR: 1D and 2D-NMR: 1H, 13C, COSY, HSQC, HMBC) methods and comparison with literature data. The essential oil composition of the plant material was analysed by GC-FID and GC-MS, simultaneously. To the best of our knowledge, secondary metabolites of this endemic species were determined for the first time. As a result, two mixtures of four entkaurane diterpenes; sidol (1) and isosidol (2), linearol (3) and isolinearol (4); four phenylethanoid glycosides; verbascoside (5), lavandulifolioside (6), leonoside A (7), leucoseptoside A (8); four flavone glycosides, apigenin-7-O-glucopyranoside (9), isoscutellarein-7-O-[6'''-O-acetyl-allopyranosyl-(12)-glucopyranoside] (10) and a mixture of apigenin-7-O-(4''-O-p-coumaroyl)-glucopyranoside (11) and apigenin-7-O-(3''-O-p-coumaroyl)-glucopyranoside (12) were elucidated. 7-O-acetyl-8-epi-loganic acid (13), an iridoid glycoside, was reported herein for the first time for genus Sideritis. In addition, major compounds of the essential oil were determined as -pinene (14.73±0.15%), -pinene (16.60±0.20%), -phellandrene (17.83±0.23%) and epi-cubebol (7.70±0.20%), respectively.

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Cite This Article

HANOĞLU, D. Y., HANOĞLU, A., YUSUFOĞLU, H., DEMİRCİ, B., BAŞER, K. H. C., ÇALIŞ, İ., YAVUZ, D. Ö. (2020). Phytochemical Investigation of Endemic Sideritis cypria Post. Records of Natural Products, Cilt: 14 - Sayı: 2, 105–115. https://ajindex.com/articles/340379

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