Journals / Veterinarium / 2001 / Cilt: 12 - Sayı: 1

Lamina propria T hücrelerinin aktivasyonu

Activation of lamina propria T cells

Pages
52–57
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, messages for IL-2 were detected from spleenic CD4*T, mixtures of SP fresh/LP fresh or SP CD4'VLP CD4" cells.

📌 3 Key Takeaways

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Objective & Hypothesis:Activation of T cells derived from the intestinal lamina propria of the pig with concovanalin 4 cc + T cells but not secretion or transcription of IL-2 while results expression of receptors for interleukin 2 on CD4+ T cells but not secretion or transcription ot IL-2 while spleen T cells secrete IL-2 in addition to receptor expression.
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Key Findings & Data:This may be a result of differences in the T cell 0| ,A accessory cell population.
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Conclusion & Impact:However, messages for IL-2 were detected from spleenic CD4*T, mixtures of SP fresh/LP fresh or SP CD4'VLP CD4" cells.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:hücre kültürü · T hücreleri · deneyler

Abstract

Activation of T cells derived from the intestinal lamina propria of the pig with concovanalin 4 cc + T cells but not secretion or transcription of IL-2 while results expression of receptors for interleukin 2 on CD4+ T cells but not secretion or transcription ot IL-2 while spleen T cells secrete IL-2 in addition to receptor expression. This may be a result of differences in the T cell 0| ,A accessory cell population. By RT-PCR experiments, no band corresponding to IL-4 was detected from CÛNA derived from CD4+ cells alone from lamina propria. However, messages for IL-2 were detected from spleenic CD4*T, mixtures of SP fresh/LP fresh or SP CD4'VLP CD4" cells.

Özet

Domuz barsak lamina propriasmdan elde edilen T hücrelerinin concovanalin A ile aktivasyonu et sonucu CD4+ hücrelerin İL-2 reseptörleri sentezlediği ancak İL-2 sentezleyemediği tespit edildi. Dalaktan elde ağ edilen T hücreleri ise hem İL-2 hem de İL-2 resptörlerini sentezleme yeteneği gösterdi. RT-PZR deneyleri ile, su lamina propria CD4+ T hücrelerinden İL-4'e ait band oluşumuna rastlanmadı. Ancak, İL-2'e ait banda dalakta CD4+1 dalak ve lamina propriadan taze hücre ile dalak CD4+/lamina propria CD4" hücre karışımlarında rastlandı.

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Cite This Article

UÇAN, U. S., STOKES, C. R., BAILEY, M. (2001). Lamina propria T hücrelerinin aktivasyonu. Veterinarium, Cilt: 12 - Sayı: 1, 52–57. https://ajindex.com/articles/333782