Journals / Türk Toraks Dergisi / 2012 / Cilt: 13 - Sayı: 3

The role of pleural fluid procalcitonin level in the diagnosis of parapneumonic pleural effusion

Parapnömonik plevral efüzyon tanısında plevral sıvı prokalsitonin düzeyinin rolü

Pages
117–121
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In our study, in PPE, a diagnostic efficiacy of pleu ral fluid and serum PCT could not be found. (Turk Toraks Derg 2012; 13: 117-21)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Procalcitonin (PCT) may lead a more rapid and spe cific result than other infectious markers in the differentation of infectious diseases from those of noninfectious conditions.
📊
Key Findings & Data:Materials and Methods: Eighty-seven patients with pleural effusion consisting of 26 transudative pelural effusion, 26 malignant pleural effusion (MPE), 24 PPE and 11 tuberculous pleural effusion (TPE) were enrolled in the study.
💡
Conclusion & Impact:Conclusion: In our study, in PPE, a diagnostic efficiacy of pleu ral fluid and serum PCT could not be found. (Turk Toraks Derg 2012; 13: 117-21)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Plevral efüzyon · Tanı · Pleural Effusion

Abstract

Objective: Procalcitonin (PCT) may lead a more rapid and spe cific result than other infectious markers in the differentation of infectious diseases from those of noninfectious conditions. In several studies, higher pleural fluid PCT levels in parapneu monic effusion (PPE) than other causes of pleural effusion has been found and it has been reported that it is a useful marker in the diagnosis of PPE. The aim of this study is to investigate the role of pleural fluid PCT levels in the diagnosis of PPE. Materials and Methods: Eighty-seven patients with pleural effusion consisting of 26 transudative pelural effusion, 26 malignant pleural effusion (MPE), 24 PPE and 11 tuberculous pleural effusion (TPE) were enrolled in the study. Results: There was no significant difference between the groups for the pleural fluid PCT, serum PCT and pleural fluid PCT/serum PCT ratio. The patients were divided into transuda tive and exudative groups and there was no difference in the pleural fluid PCT and serum PCT between these two groups. In the PPE group, the correlation between pleural fluid PCT level and pleural fluid albumin, protein, LDH, glucose and ADA was studied and no correlation was found. Conclusion: In our study, in PPE, a diagnostic efficiacy of pleu ral fluid and serum PCT could not be found. (Turk Toraks Derg 2012; 13: 117-21)

Özet

Amaç: Prokalsitonin, infeksiyöz hastalıkları noninfeksiyöz hasta lıklardan ayrımda diğer infeksiyon belirteçlerine göre erken ve oldukça yüksek özgüllükte sonuç verebilmektedir. Yapılan bazı çalışmalarda, plevral sıvı prokalsitonin (PCT) düzeyinin parapnö monik efüzyon (PPE)’da diğer nedenlere bağlı sıvılara göre daha yüksek olduğu bulunmuş ve tanıda yararlı bir belirteç olduğu bildirilmiştir. Bu çalışmada amaç, plevral sıvı PCT düzeyinin PPE tanısındaki rolünü araştırmaktır. Gereç ve Yöntem: Çalışmaya 26 transüda, 26 malign plevral efüzyon (MPE), 24 PPE ve 11 tüberküloz plevral efüzyon (TPE) olmak üzere toplam 87 pleval sıvılı hasta alındı. Bulgular: Gruplar arasında plevral sıvı PCT, serum PCT düzeyi ve plevral sıvı PCT/serum PCT oranı bakımından anlamlı fark yoktu. Hastalar eksüda ve transüda gruplarına ayrıldı ve iki grup arasın da plevral sıvı PCT ve serum PCT düzeyi açısından fark saptan madı. PPE grubunda plevral PCT düzeyi ile plevral sıvı albümin, protein, LDH, glukoz ve ADA düzeyleri arasındaki korelasyon araştırıldı ve herhangi bir korelasyon bulunamadı. Sonuç: Çalışmamızda PPE’da, plevral sıvı PCT ve serum PCT ölçümünün tanısal etkinliği gösterilemedi. (Turk Toraks Derg 2012; 13: 117-21)

🔖

Cite This Article

KOÇER, B. C., ÇİLEDAĞ, A., IŞIK, M. E., YILMAZ, A., GÜVEN, S. F., YÜKSEL, C., POYRAZ, B., RAD, A. Y., KUTLAY, H., ÇELİK, G., KAYA, A. (2012). The role of pleural fluid procalcitonin level in the diagnosis of parapneumonic pleural effusion. Türk Toraks Dergisi, Cilt: 13 - Sayı: 3, 117–121. https://ajindex.com/articles/329497

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Assicot M, Gendrel D, Carsin H, et al. High serum procalci tonin concentrations in patients with sepsis and infection. Lancet 1993;341:515-8
  2. Ertuğrul Ö, Ertuğrul MB. Prokalsitonin ve İnfeksiyon. Klimik Dergisi 2005;18:59-62
  3. Hatzistilianou M. Diagnostic and prognostic role of procalci tonin in infections. ScientificWorldJournal 2010;10:1941-6
  4. Gendrel D, Raymond J, Coste J, et al. Comparison of procal citonin with C-reactive protein, interleukin 6 and interferon alpha for differentitation of bacterial vs. viral infections. Pediatr Infect Dis J 1999;18:875-81
  5. Light RW. Clinical manifestations and useful tests. In: Light RW (Ed). Pleural disease. Baltimore;Williams & Wilkins, 1995:36-74
  6. Light RW. Parapneumonic Effusions and Empyema in Light RW (ed). Pleural diseases Phidelphia PA Williams and Wilkins 2007:170-210
  7. Topolcan O, Holubec L, Polivkova V, et al. Tumor markers in pleural effusions. Anticancer Res 2007;27:1921-4
  8. Porcel JM, Vives M, Cao G, et al. Biomarkers of infection for the differential diagnosis of pleural effusions. Eur Respir J 2009;34:1383-9
  9. Lin MC, Chen YC, Wu JT, et al. Diagnostic and prognostic values of pleural fluid procalcitonin in parapneumonic pleu ral effusions. Chest 2009;136:205-11
  10. Wang CY, Hsiao YC, Jerng JS, et al. Diagnostic value of procalcitonin in pleural effusions. Eur J Clin Microbiol Infect Dis 2011;30:313-8
  11. San José ME, Valdés L, Vizcaíno LH, et al. Procalcitonin, C-reactive protein, and cell counts in the diagnosis of parap neumonic pleural effusions. J Investig Med 2010;58:971-6
  12. Ko YC, Wu WP, Hsu CS, et al. Serum and pleural fluid procal citonin in predicting bacterial infection in patients with para pneumonic effusion. J Korean Med Sci 2009;24:398-402
  13. Cakir E, Deniz O, Ozcan O, et al. Pleural fluid and serum procalcitonin as diagnostic tools in tuberculous pleurisy. Clin Biochem 2005;38:234-8.