Journals / Türk Toraks Dergisi / 2011 / Cilt: 12 - Sayı: 1

Study of cough reflex sensitivity in a group of Egyptian patients with chronic hepatitis C virus infection

Kronik hepatit C virüs enfeksiyonlu Mısırlı bir hasta grubunda öksürük refleksi duyarlılığı çalışması

Pages
14–18
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Bulgular: log C5 was significantly lower in the three groups of patients than controls (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Amaç: The aim of this work was to study the effect of chronic hepatitis C viraemia on cough reflex sensitivity.
📊
Key Findings & Data:Gereç ve Yöntem: Cough reflex sensitivity was tested by Capsaicin cough provocation in 57 patients (33.66±6.809 years old [M±SD]) with chronic HCV infection.
💡
Conclusion & Impact:Bulgular: log C5 was significantly lower in the three groups of patients than controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Amaç: The aim of this work was to study the effect of chronic hepatitis C viraemia on cough reflex sensitivity. Gereç ve Yöntem: Cough reflex sensitivity was tested by Capsaicin cough provocation in 57 patients (33.66±6.809 years old [M±SD]) with chronic HCV infection. Patients were divided into 3 subgroups: group I: 22 with normal Alanine aminotransferase (ALT) and no evidence of liver cirrhosis on ultrasound, group II: 19 with elevated ALT and active hepatitis but no cirrhosis on liver biopsy (8 on treatment) and group III: 16 with elevated ALT and positive cirrhosis on liver biopsy (6 on treatment). 23 normal age matched subjects were tested as controls. Bulgular: log C5 was significantly lower in the three groups of patients than controls (p

Özet

Objective: The aim of this work was to study the effect of chronic hepatitis C viraemia on cough reflex sensitivity. Material and Method: Cough reflex sensitivity was tested by Capsaicin cough provocation in 57 patients (33.66±6.809 years old [M±SD]) with chronic HCV infection. Patients were divided into 3 subgroups: group I: 22 with normal Alanine aminotransferase (ALT) and no evidence of liver cirrhosis on ultrasound, group II: 19 with elevated ALT and active hepatitis but no cirrhosis on liver biopsy (8 on treatment) and group III: 16 with elevated ALT and positive cirrhosis on liver biopsy (6 on treatment). 23 normal age matched subjects were tested as controls. Results: log C5 was significantly lower in the three groups of patients than controls (p

🔖

Cite This Article

ALSALAHY, M. M., SHAHIN, Y. A., BELAL, K. M. (2022). Study of cough reflex sensitivity in a group of Egyptian patients with chronic hepatitis C virus infection. Türk Toraks Dergisi, Cilt: 12 - Sayı: 1, 14–18. https://ajindex.com/articles/655368

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Moorman J, Saad M, Kosseifi S, et al. Hepatitis C Virus and the Lung: Implications for Therapy. Chest 2005; 128; 2882-92
  2. Kanazawa H, Mamoto T, Hirata K, et al. Interferon therapy induces the improvement of lung function by inhaled corticosteroid therapy in asthmatic patients with chronic hepatitis C virus infection: a preliminary study. Chest 2003; 123: 600-3
  3. Kanazawa H, Hirata K, Yoshikawa J. Accelerated decline of lung function in COPD patients with chronic hepatitis C virus infection: a preliminary study based on small numbers of patients. Chest 2003; 123: 596-9
  4. Alter MJ, Margolis HS, Krawczynski K, et al. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team. N Engl J Med 1992; 327: 1899-905
  5. WHO; Global Burden of Disease (GBD) for Hepatitis C: WHO Working Group. J Clin Pharmacol January 2004 vol. 44 no. 1 20-29 6. Darwish MA, Faris R, Darwish N et al. Hepatitis C and cirrhotic liver disease in the Nile delta of Egypt: a communitybased study. Am J Trop Med Hyg. 2001; 64: 147-53
  6. Dicpinigaitis P, Sitkauskiene B, Stravinskaite K, et al. R. Effect of smoking cessation on cough reflex sensitivity. Eur Respir J 2006; 28: 786-90
  7. Dicpinigaitis PV, Rauf K. The influence of gender on cough reflex sensitivity. Chest 1998; 113: 1319-21
  8. Gattoni A, Cecere A, Romano C, et al. Hepatitis C and systemic diseases. The Clinical Therapeutic 1997; 148: 133-51
  9. Lee AS, Oon CJ, Chee MK, et al. Quantitation of hepatitis C viraemia by a competitive reverse transcription-polymerase chain reaction system. Annals of the Academy of Medicine Singapore 1996; 25: 98-102
  10. Bbruder D, Srikiatkhachorn A, Enelow R. Cellular immunity and lung injury in respiratory virus infection. Viral Immunology 2006; 19: 147-55. 12 Shimizu T, Mochizuki H, Morikawa A. Effect of influenza A virus infection on acid-induced cough response in children with asthma. Eur Respir J 1997; 10: 71-4
  11. Jacoby D. Pathophysiology of airway viral infections. Pulmonary Pharmacology & Therapeutics 1996; 17: 333-6
  12. Footitt J, Johnston S. Cough and viruses in airways disease: Mechanisms. Pulmonary Pharmacology & Therapeutics 2009; 22: 108-13
  13. Saadoun D, Landau DA, Calabrese LH, et al. Hepatitis C-associated mixed cryo-globulinaemia: a crossroad between autoimmunity and lymphoproliferation. Rheumatology 2007; 46: 1234-42
  14. Brunetti G, Delmastro M, Nava S, Furione M. Detection of HCV-RNA in