Journals / Tüberküloz ve Toraks / 2017 / Cilt: 65 - Sayı: 1

Retrospective evaluation of patients with organizing pneumonia: is cryptogenic organizing pneumonia different from secondary organizing pneumonia?

Organize pnömonili olguların retrospektif değerlendirilmesi: Kriptojenik organize pnömoni sekonder organize pnömoniden farklı mıdır?

Pages
1–8
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although it is not asserted, cyst hidatic and anthracosis could be kept in mind for the list of underlyingethiologies for secondary OP.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Organizing pneumonia (OP) is an uncommon clinic opathological situation among lung diseases.
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Key Findings & Data:It was also aimed to make a comparison betweenCOP and secondary OP patients.Materials and Methods: One hundred sixty-five patients diagnosed as OP pathologically in the 10 year period from August 2003 toAugust 2013 were included into that study.
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Conclusion & Impact:Although it is not asserted, cyst hidatic and anthracosis could be kept in mind for the list of underlyingethiologies for secondary OP.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Organizing pneumonia (OP) is an uncommon clinic opathological situation among lung diseases. If no underlyingcause can be detected, it is named as cryptogenic OP (COP). In this study, the etiologic and clinical characteristics of patientsdiagnosed as OP in our hospital in the last ten years were evaluated retrospectively. It was also aimed to make a comparison betweenCOP and secondary OP patients.Materials and Methods: One hundred sixty-five patients diagnosed as OP pathologically in the 10 year period from August 2003 toAugust 2013 were included into that study. Patients' data were evaluated retrospectively from the medical records.Results: One hundred sixty five patients pathologically diagnosed as OP were included. Diagnostic methods were trans-thoracicfine-needle biopsy (TTFNB) in 89 (53.9%) patients, open lung biopsy (lobectomy, wedge resection, segmentectomy) in 52 (31.5%)patients and transbronchial biyopsy (TBB) in 24 (14.5%) patients. One hundred (60.6%) of the patients were defined as COP and65 (39.4%) as secondary OP. Cough, fatigue and dyspnea werethe most common symptoms on admission. We detected OP casessecondary to anthracosis and cyst hydatic besides other wellknown etiologies. In 61 patients, the main radiologic manifestationwas multiple bilateral patchy consolidation typical for OP. In 76patients focal lesions (solid mass, cavitating mass lesion) and in 6patients infiltrative opacities were detected radiologically. Conclusion: There is no difference between properties of OP from clinical, laboratory and radiologic finding sin the criptogenic and seconder form of OP. Although it is not asserted, cyst hidatic and anthracosis could be kept in mind for the list of underlyingethiologies for secondary OP.

Özet

Giriş: Organize pnömoni (OP) akciğer hastalıkları içerisinde nadir görülen klinik opatolojik bir durumdur. Gerçek insidansı ve prevalansı bilinmemektedir. Altta yatan hastalık ya da neden belli değilse kriptojenik organize pnömoni (KOP) olarak adlandırılır. Bu çalışmamızda son 10 yılda hastanemizde tanı alan organize pnömoni olgularının retrospektif olarak, etyolojik ve klinik özelliklerinin değerlendirilmesi ve kriptojenik ve sekonder OP hastalarının birbiri ile karşılaştırılması amaçlanmıştır.Materyal ve Metod: Bu çalışmaya Ağustos 2003-Ağustos 2013 tarihleri arasında patolojik doku tanısı OP gelen 165 hasta dahil edildi. Hasta bilgileri retrospektif olarak hastane dosyalarından incelendi.Bulgular: Çalışmaya patolojik olarak OP tanısı konulmuş 165 hasta dahil edildi. Hastaların 89 (%53.9)'una transtorasik ince iğne aspirasyon biyopsisi (TTİAB), 52 (%31.5)'sine cerrahi yöntemle (lobektomi, wedge rezeksiyon, segmentektomi), 24 (%14.5)' üne transbronşiyal biyopsi (TBB) ile tanı konulmuştu. 100 (%60.6) hastanın KOP, 65 (%39.4) hastanın da sekonder OP olduğu belirlendi. En yaygın görülen semptomlar; öksürük, halsizlik, dispne idi. Elli beş (%44.7) hastada restriktif, 26 (%21.2) hastada obstrüktif solunum fonksiyon bozukluğuna rastlandı. Çalışmamızda sekonder organize pnömoniye sebep olan bilinen etyolojik ajanlara ek olarak antrokozise ve kist hidatiğe bağlı olarak gelişen organize pnömoni olguları saptadık. Altmış dokuz hastada OP'un tipik radyolojik görünümü olan yamalı vasıfta bilateral multipl opasiteler, 76 hastada fokal lezyonlar (solid kitle, kaviter kitle), 6 hastada da infiltratif opasiteler izlendi.Sonuç: OP'un kriptojenik ve sekonder formlarında OP'a ilişkin klinik, radyolojik ve laboratuvar özellikler açısından fark yoktur. Ülkemizde sekonder OP tanısı konulan hastalarda, etyolojide kist hidatik ve antrokoziste akılda tutulmalıdır.

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Cite This Article

DEMİRAĞ, F., ERDOĞAN, Y., DADALI, Y., YILMAZ, S., KOÇER, B. C., BÜYÜKYAYLACI, S. Ö., AKINCI, B. Ö. (2022). Retrospective evaluation of patients with organizing pneumonia: is cryptogenic organizing pneumonia different from secondary organizing pneumonia?. Tüberküloz ve Toraks, Cilt: 65 - Sayı: 1, 1–8. https://ajindex.com/articles/618483

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References (14)

  1. Drakopanagiotakis F, Paschalaki K, Abu-Hijleh M, Aswad B, Karagianidis N, Kastanakis E, et al. Cryptogenic and secondary organizing pneumonia clinical presentation, radiographic findings, treatment response, and prognosis. Chest 2011:139:893-900
  2. Maldonado F, Daniels CE, Hoffman EA, Yi ES, Ryu JH. Focal organizing pneumonia on surgical lungbiopsy: causes, clinico radiologic features, and outcomes. Chest 2007;132:1579-83
  3. Craig PS, Manus DP, Lightowlers MW, Chabalgoity JA, Garcia HH, Gavidia CM, et al. Preventionand control of cystic echinococcosis. Lancet Infect Dis 2007;7:385-94
  4. Sakamoto T, Gutierrez C. Pulmonary complications of cystic echinococcosis in children Urguay. Pathol Int 2005;55:497-503
  5. Cavazza A, Nigrisoli E, De Marco L, Paci M, Annessi V, Agostini L, et al. Bronchiolitis obliterans-organizing pneumonia (BOOP) containing asbestos bodies: clinicopathological study of a case. Pathologica 2001;93:681-4
  6. Vasu TS, Cavallazzi R, Hirani A, Sharma D, Weibel SB, Kane GC. Clinical and radiologic distinctions between secondary bronchiolitis obliterans organizing pneumonia and cryptogenic organizing pneumonia. Respir Care 2009;54:1028-32
  7. Epler GR. Bronchiolitis obliterans organizing pneumonia: definition and clinical features. Chest 1992;102(Suppl):S2-6
  8. Alasaly K, Muller N, Ostrow DN, Champion P, FitzGerald JM. Cryptogenic organizing pneumonia. A report of 25 cases and a review of the literature. Medicine (Baltimore) 1995;74:201-11
  9. Cottin V, Cordier JF. Cryptogenic organizing pneumonia. Semin Respir Crit Care Med 2012;33:462-75
  10. Gul A, Yilmazbayhan D, Buyukbabani N, Lie JT, Tunaci M, Tunaci A, et al. Organizing pneumonia associated with pulmonary artery aneurysms in Behcet's disease. Rheumatology (Oxford) 1999;38:1285-9
  11. Oymak FS, Demirbaş HM, Mavili E, Akgun H, Gulmez I, Demir R, et al. Bronchiolitis obliterans organizing pneumonia. Clinical and roentgenological features in 26 cases. Respiration 2005;72:254-62
  12. King TE Jr, Mortenson RL. Cryptogenic organizing pneumonitis. The North American experience. Chest 1992;102(Suppl 1):S8-S13
  13. Izumi T, Kitaichi M, Nishimura K, Nagai S. Bronchiolitis obliterans organizing pneumonia. Clinical features and differential diagnosis. Chest 1992;102:715-9
  14. Travis W, Costabel U, Hansell DM, King TE, Lynch DA, Nicholson AG, et al. An official American Thoracic Society/ European Respiratory Society statement: Update of the international multidisciplinary classification of t