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Journals / Türk Toraks Dergisi / 2010 / Cilt: 11 - Sayı: 1

Plevral sıvıların transüda eksüda ayırımında yeni bir yaklaşım

A new approach in distinguishing exudative and transudative pleural effusions

Yasin YILDIZ
Abdurrahman ŞENYİĞİT
Yusuf ÇELİK
Levent AKYILDIZ
Güngör ATEŞ
Sedat ÇOLAKOĞLU
Hasan BAYRAM
Sacide Rana IŞIK
Füsun TOPÇU
Pages
14–18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Proving our proposal would be useful in clinical practices.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Light's criteria, which were accepted in 1972 for the differential diagnosis of pleural effusions as transudates or exudates, are widely used worldwide.
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Key Findings & Data:Material and Method: These criteria were evaluated in 451 patients in our study.
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Conclusion & Impact:Proving our proposal would be useful in clinical practices.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Light's criteria, which were accepted in 1972 for the differential diagnosis of pleural effusions as transudates or exudates, are widely used worldwide. It has been reported in various studies that Light's criteria have lower specificity, and new recommendations have emerged. The discriminative ability of Light's criteria and adapted formulas, which are our new proposal, were studied by Receiver Operating Characteristics (ROCs) analysis and Area Under the Curves (AUCs). Material and Method: These criteria were evaluated in 451 patients in our study. Of these cases, 151 had transudates, while 300 patients presented with exudates. Results: AUCs of Light's criteria (P/Sprot, P/SLDH, PLDH) were measured as 0.931 (95%CI: 0.899-0.963), 0.936(95%CI: 0.904- 0967) and 0.957(95%CI: 0.934-0.981), respectively, and the differences between the measured values were found to be statistically significant (p<.001). AUCs of our new adapted formulas (F-1, F-2, F-3) were found to be slightly higher than those of Light's criteria, with the values of 0.987(95%CI: 0.976- 0.998), 0.935(95%CI 0:.908-0.963) and 0.980(95%CI: 0.966- 0.993), respectively, and the differences were also significant (p<.001). Conclusion: In our opinion, further studies are needed with a wider study population to determine the value of the new formulas in differentiating exudative and transudative pleural effusions. Proving our proposal would be useful in clinical practices.

Özet

Amaç: Light kriterleri plevral sıvıların transüda eksüda ayırımında ilk tanımlandıkları 1972 yılından beri tüm dünyada yaygın bir şekilde kullanılmaktadırlar. Ancak daha sonraki çeşitli çalışmalarda Light kriterlerinin spesifisitelerinin düşük oldukları bildirilmiş ve yeni öneriler gündeme gelmiştir. Light kriterleri ile bizim önerdiğimiz yeni formüllerin ayırt edici yetenekleri Receiver Operating Characteristics (ROCs) incelemeleri ve Area Under the Curves (AUCs) ile değerlendirildi. Gereç ve Yöntem: Çalışmamızda toplam 451 hasta, Light kriterleri ve bizim önerdiğimiz formüllerle değerlendirildi. Bu hastaların plevral sıvılarının 151'i transüda, 300'ü eksüdaydı. Light kriterleri ve bizim formüllerimiz Receiver Operating Characteristics (ROCs) analizi ve Area Under the Curves (AUCs) ile karşılaştırıldı. Bulgular: Light kriterlerinin AUC değerleri (P/Sprot, P/SLDH, PLDH) sırasıyla .931 (%95 CI: .899-.963), .936(%95 CI: .904-.967) ve .957(%95 CI: .934-.981) idi ve değişkenler istatistiksel olarak anlamlıydı (p<.001). Diğer taraftan, bizim formüllerimizin AUCs değerleri (F-1, F-2, F-3) sırasıyla .987(%95 CI:.976-.998), .935(%95 CI:.908-.963) ve .980(%95 CI:.966-.993) idi ve değişkenler anlamlıydı (p<.001). Sonuç: Mevcut veriler, formüllerimizin transüda eksüda ayırımında daha geniş serili çalışmalarda değerlendirilmesi gerektiğini düşündürmüştür. Formüllerimizin klinik pratikte yararlı olabileceğini düşünmekteyiz.

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Cite This Article

YILDIZ, Y., ŞENYİĞİT, A., ÇELİK, Y., AKYILDIZ, L., ATEŞ, G., ÇOLAKOĞLU, S., BAYRAM, H., IŞIK, S. R., TOPÇU, F. (2010). Plevral sıvıların transüda eksüda ayırımında yeni bir yaklaşım. Türk Toraks Dergisi, Cilt: 11 - Sayı: 1, 14–18. https://ajindex.com/articles/328842

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