Journals / Türk Üroloji Dergisi/Turkish Journal of Urology / 2011 / Cilt: 37 - Sayı: 3

Rekürren kalsiyum oksalat taş hastalarında metebolik değerlendirme

Metabolic evaluation in patients with recurrent calcium oxalate stones

Pages
246–251
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These metabolic abnormalities should be detected and corrected to prevent the recurrence of stones.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aimed to evaluate the metabolic changes in patients with recurrent calcium oxalate stones.
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Key Findings & Data:Materials and methods: We evaluated 143 patients with recurrent oxalate stones and measured serum calcium, phosphate, creatinine, urate, and parathormone.
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Conclusion & Impact:These metabolic abnormalities should be detected and corrected to prevent the recurrence of stones.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: This study aimed to evaluate the metabolic changes in patients with recurrent calcium oxalate stones. Materials and methods: We evaluated 143 patients with recurrent oxalate stones and measured serum calcium, phosphate, creatinine, urate, and parathormone. In addition, 24-h urinary output was monitored and collected for the measurement of total volume, pH, citrate, calcium, urate, oxalate, phosphorus, sodium, and magnesium. Results: The mean age of the patients was 42.8±10.8 years, and 132 out of 143 patients (92.3%) had metabolic abnormalities. There were no metabolic abnormalities in only 11 (7.7%) patients. Thirty (20.1%) patients only had one metabolic abnormality, and 102 (71.3%) patients had multiple metabolic abnormalities. Hyperoxaluria was the major metabolic abnormality (64.4%), but we also detected low urinary volume, hypercalciuria, hypocitraturia, hypernatriuria, and hyperuricosuria in 66 (46.2%), 47 (32.8%), 47 (32.8%), 44 (30.8%), and 21 (14.7%) patients, respectively. Conclusion: There were several metabolic abnormalities in patients with recurrent calcium oxalate stones, and the most important were hyperoxaluria, hypercalciuria, hypocitraturia, and low urinary volume. These metabolic abnormalities should be detected and corrected to prevent the recurrence of stones.

Özet

Amaç: Bu çalışmada rekürren kalsiyum oksalat taş hastalarında metabolik değişikliklerin değerlendirilmesi amaçlanmıştır. Gereç ve yöntem: Rekürren kalsiyum oksalat taşı olan 143 hasta değerlendirildi ve serumda kalsiyum, fosfat, kreatinin, ürat ve parathormon ölçüldü. Ayrıca 24 saatlik idrarda total hacim, pH, sitrat, kalsiyum, ürat, oksalat, fosfor, sodyum ve magnezyum bakıldı. Bulgular: Hastaların ortalama yaşı 42.8±10.8 olarak saptandı. Çalışmaya alınan 143 hastanın 132’sinde (%92.3) metabolik bozukluk saptandı. Sadece 11 (%7.7) hastada metabolik bozukluk yoktu. Metabolik bozukluk saptanan hastaların 102’sinde (%71.3) mikst metabolik bozukluk varken 30’unda (%20.1) tek metabolik bozukluk belirlendi. Hiperoksalüri (%64.4) temel metabolik bozukluk olarak ortaya çıktı. Ancak düşük idrar hacmi 66 (%46.2), hiperkalsiuri 47 (%32.8), hipositratüri 47 (%32.8), hipernatriüri 44 (%30.8) ve hiperürikozüri 21 (%14.7) hastada belirlendi. Sonuç: Rekürren kalsiyum oksalat taş hastalarında çeşitli metabolik bozukluklar vardır. Bu metabolik bozukluklardan en önemlileri hiperoksalüri, hiperkalisüri, hipositratüri ve düşük idrar hacmidir. Bu metabolik bozukluklar belirlenmeli ve taş rekürrenslerinin önlenmesi için düzeltilmelidir.

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Cite This Article

KIRAÇ, M., KÜPELİ, B., KARAOĞLAN, Ü., BOZKIRLI, İ. (2011). Rekürren kalsiyum oksalat taş hastalarında metebolik değerlendirme. Türk Üroloji Dergisi/Turkish Journal of Urology, Cilt: 37 - Sayı: 3, 246–251. https://ajindex.com/articles/328087

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