Journals / Molecular Imaging and Radionuclide Therapy / 2012 / Cilt: 21 - Sayı: 2

Koroner arter hastalığı olan kadınlarda gated SPECT miyokard perfüzyon sintigrafisinin rolü: Korelatif çalışma

The role of myocardial perfusion gated SPECT study in women with coronary artery disease: A correlative study

Pages
69–74
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Gated MPS study is recommended to achieve the final decision for myocardial ischemia in the cases with CAD and raw data must always be evaluated to avoid attenuation artifacts. (MIRT 2012;21:69-74)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to evaluate the role of gated myocardial perfusion SPECT (MPS) and to investigate whether only the invasive coronary angiography (CAG) is sufficient in the diagnosis of the coronary artery disease (CAD) in women.
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Key Findings & Data:Material and Methods: Sixty-four women (62±10 years) with known CAD were included in this study.
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Conclusion & Impact:Gated MPS study is recommended to achieve the final decision for myocardial ischemia in the cases with CAD and raw data must always be evaluated to avoid attenuation artifacts. (MIRT 2012;21:69-74)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to evaluate the role of gated myocardial perfusion SPECT (MPS) and to investigate whether only the invasive coronary angiography (CAG) is sufficient in the diagnosis of the coronary artery disease (CAD) in women. Material and Methods: Sixty-four women (62±10 years) with known CAD were included in this study. They had echocardiography (ECHO), stress/rest gated MPS and invasive CAG. Coronary stenosis as of > 50 % in invasive CAG was accepted as significant. Gated MPS data were compared with invasive CAG and ECHO. Results: Invasive CAG results were abnormal in 34 patients, and normal in 30 cases. Myocardial ischemia was detected by gated MPS in 22/ 30 cases with normal invasive CAG, 6 had mild coronary stenosis in major coronary arteries ranging from 30% to 50% in invasive CAG. 16/ 22 women were diagnosed as metabolic syndrome according to MetSend Diagnostic Criteria and only 8 of 30 patients with normal invasive CAG had false positive MPS data on the reevaluation by a nuclear cardiologist. Conclusion: We think that invasive coronary angiography method is not sufficient alone in the diagnosis of CAD in women. Gated MPS study is recommended to achieve the final decision for myocardial ischemia in the cases with CAD and raw data must always be evaluated to avoid attenuation artifacts. (MIRT 2012;21:69-74)

Özet

Amaç: Kadınlarda koroner arter hastalığının tanısında gated miyokardiyal perfüzyon SPECT (MPS) rolünü ve invaziv koroner anjiyografinin (KAG) tek başına yeterli olup olmadığını değerlendirmeyi amaçladık. Gereç ve Yöntemler: Bilinen koroner arter hastalığı olan 64 kadın (62±10 yıl) çalışmaya dahil edildi. Tüm hastaların ECHO, egzersiz / istirahat gated MPS ve invaziv KAG yapılmıştı. İnvaziv KAG’de koroner darlığı >50% ciddi hastalık olarak kabul edildi. Gated MPS verileri, invaziv KAG ve ECHO verileri ile karşılaştırıldı. Bulgular: İnvaziv KAG sonuçları 34 hastada anormaldi ve 30 hastada normaldi. Koroner anjiyografisi normal olan 30 hastanın 22’sinde gated MPS ile miyokardiyal iskemi saptandı, bunların 6 tanesinin %30 ile 50 arası hafif koroner darlığı vardı. On altı hasta MetSend tanı kriterlerine göre metabolik sendrom tanısı aldı. Nükleer kardiyolog tarafından yeniden değerlendirmede koroner anjiyografisi normal bulunan 30 hastanın 8’inde MPS verisi yalancı pozitif rapor edildi. Sonuç: Biz, kadınlarda koroner arter hastalığının tanısında invaziv koroner anjiyografi metodunun tek başına etkin olmadığını düşünüyoruz. Koroner arter hastalığı olan vakalarda miyokart iskemisi kesin tanısı gated MPS çalışması ile konulmalıdır ve atenüasyon artefaktları açısından ham data görüntüleri daima değerlendirilmelidir. (MIRT 2012;21:69-74)

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Cite This Article

AKALIN, E. N., YAYLALI, O., KIRAÇ, F. S., YÜKSEL, D. G., KILIÇ, M. (2012). Koroner arter hastalığı olan kadınlarda gated SPECT miyokard perfüzyon sintigrafisinin rolü: Korelatif çalışma. Molecular Imaging and Radionuclide Therapy, Cilt: 21 - Sayı: 2, 69–74. https://ajindex.com/articles/295258

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