Journals / Türk Uyku Tıbbı Dergisi / 2020 / Cilt: 7 - Sayı: 1

Coexistence of Obstructive Sleep Apnea Syndrome and Narcolepsy: Four Cases

Obstrüktif Uyku Apne Sendromu ve Narkolepsi Birlikteliği: Dört Olgu

Pages
36–40
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

By presenting the approach to these four cases, we aimed to identify the causes and possible mechanisms about coexistence between narcolepsy and sleep apnea syndrome.

📌 3 Key Takeaways

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Objective & Hypothesis:Excessive daytime sleepiness is a common clinical application of Obstructive Sleep Apnea syndrome and narcolepsy patients.
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Key Findings & Data:In our four reported cases, there were obstructive sleep apnea syndrome and narcolepsy type 1 coexistence.
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Conclusion & Impact:By presenting the approach to these four cases, we aimed to identify the causes and possible mechanisms about coexistence between narcolepsy and sleep apnea syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Excessive daytime sleepiness is a common clinical application of Obstructive Sleep Apnea syndrome and narcolepsy patients. Although both medical conditions can be different in extensive daytime sleepiness features and accompanying symptomatology, distinctive features may be masked in some cases. In our four reported cases, there were obstructive sleep apnea syndrome and narcolepsy type 1 coexistence. We aimed to discuss the possibility of this condition being comorbidity, the possibility of masking the type clinics in their association or the possibility of causing each other’s risk factors. In two of the reported cases, although excessive daytime sleepiness was not restful and typical cataplexy attacks were not described in the beginning, cataplexy attacks started to be defined even when excessive daytime sleepiness persisted when they were treated with Sleep Apnea syndrome. As a result of repeated diagnostic tests, they were diagnosed with narcolepsy in addition to Sleep Apnea syndrome. In the other two cases, excessive daytime sleepiness and cataplexy attacks, and diagnostic tests indicated type 1 narcolepsy, but it was observed that the Body Mass indexes were increased in the clinical follow-up and sleep apnea syndrome was diagnosed with repeated test. By presenting the approach to these four cases, we aimed to identify the causes and possible mechanisms about coexistence between narcolepsy and sleep apnea syndrome.

Özet

Obstrüktif Uyku Apne sendromu ve narkolepsi hastalarının klinik başvurusu ortak olarak gündüz aşırı uykululuğudur. Her ne kadar her iki medikal durumun gündüz aşırı uykululuk özellikleri ve eşlik eden semptomatolojisi birbirinden farklı olabilse de bazı olgularda ayırt edici özellikler maskelenebilmektedir. Bildirilen dört olgumuzda Obstrüktif Uyku Apne sendromu ve narkolepsi tip 1 birlikteliği mevcuttur. Bu durumun komorbidite olabilmesi, birlikteliklerinde tipik kliniklerini maskeleyebilmeleri veya birbirlerinin risk faktörlerini doğurma olasılığını tartışmayı hedefledik. Bildirilerilen olguların ikisinde gündüz aşırı uykululuğu ile başvurusunda, uyku ataklarının dinlendirici olmaması ve tipik katapleksi atakları tanımlanmamasına rağmen tespit edilen Uyku Apne sendromu tedavisini aldıklarında gündüz aşırı uykululukları devam etse de katapleksi atakları tanımlanmaya başlanmıştır. Tekrarlanan tanı testleri sonucunda, uyku apne sendromuna ek olarak narkolepsi tanısı almışlardır. Diğer iki olgumuzda ise gündüz aşırı uykululuğu ve katapleksi atakları ile tanı testleri tip 1 narkolepsiye işaret etse de klinik izlemde Vücut Kitle indekslerinin artışı ile de tekrarlanan tanı testinde Uyku Apne sendromu eşlik ettiği görülmüştür. Bu dört olguya yaklaşımı bildirerek nedenlerini ve olası mekanizmalarını belirtmeyi hedefledik.

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Cite This Article

DİBEK, D. M., BULUT, O., FERİK, S., ÇELİK, A. Ö., ÖZTURA, İ., BALKAN, B. (2020). Coexistence of Obstructive Sleep Apnea Syndrome and Narcolepsy: Four Cases. Türk Uyku Tıbbı Dergisi, Cilt: 7 - Sayı: 1, 36–40. https://ajindex.com/articles/327956

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