Journals / Türk Uyku Tıbbı Dergisi / 2019 / Cilt: 6 - Sayı: 2

The Relationship Between Restless Legs Syndrome and Cardiovascular Risk Factors

Huzursuz Bacaklar Sendromu ve Kardiyovasküler Risk Faktörleri İlişkisi

Pages
29–36
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Şenay Aydın*,1, Cengiz Özdemir*, Sinem Nedime Sökücü*

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Restless Legs syndrome (RLS) is one of the common sleep disorders in the community.
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Key Findings & Data:Materials and Methods: The study included 107 patients (group 1) diagnosed with RLS according to the diagnostic criteria recommended by the international RLS study group and 97 patients with the diagnosis of simple snoring (group 2) among the patients who were prescribed a diagnosis of sleep disorder in the sleep laboratory.
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Conclusion & Impact:Şenay Aydın*,1, Cengiz Özdemir*, Sinem Nedime Sökücü*
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Restless Legs syndrome (RLS) is one of the common sleep disorders in the community. There are many studies on the relationship between sleep disorders and diabetes, hypertension, hyperlipidemia, obesity, and metabolic dysregulation. However, the results are contradicting in the studies conducted in cases with RLS. In this study, we retrospectively examined the possible relationship between cardiovascular risk factors and RLS. Materials and Methods: The study included 107 patients (group 1) diagnosed with RLS according to the diagnostic criteria recommended by the international RLS study group and 97 patients with the diagnosis of simple snoring (group 2) among the patients who were prescribed a diagnosis of sleep disorder in the sleep laboratory. Demographic, laboratory and polysomnographic data of all cases were retrospectively reviewed. Results: There was no significant difference between the groups in terms of age, gender, smoking, and alcohol use, however, weight, neck circumference, waist circumference, and body mass index were detected significantly higher (p=0.008, p=0.020, p=0.001, p=0.002, respectively). In addition, diastolic and systolic arterial blood pressure values and total cholesterol, low density lipoprotein-cholesterol, and triglyceride levels measured at the night of the examination were significantly different between the groups, and the presence of Metabolic syndrome was observed significantly higher in the RLS group (p=0.001, p=0.001, p=0.024, p=0.033, p=0.020, p=0.002, respectively). Conclusion: The incidence of hypertension, hyperlipidemia, obesity, and Metabolic syndrome increases in RLS patients. Further prospective studies are needed to elucidate the potential mechanisms underlying this correlation between the RLS and cardiovascular risk factors. Şenay Aydın*,1, Cengiz Özdemir*, Sinem Nedime Sökücü*

Özet

Amaç: Huzursuz Bacaklar sendromu (HBS) toplumda sık gözlenen uyku bozukluklarından biridir. Uyku bozuklukları ile diyabet, hipertansiyon, hiperlipidemi, obezite ve metabolik disregülasyon arasındaki ilişkiye dair birçok çalışma mevcuttur. Ancak HBS’li olgularda yapılan çalışmalarda sonuçlar çelişkilidir. Biz bu çalışmada HBS ile kardiyovasküler risk faktörleri arasındaki olası ilişkiyi retrospektif olarak inceledik. Gereç ve Yöntem: Çalışmaya uyku laboratuvarında uyku bozukluğu ön tanısı ile polisomnografisi yapılmış ve uluslararası HBS çalışma grubu tarafından önerilen tanı ölçütlerini karşılayan 107 HBS’li hasta (grup 1) ile basit horlama tanısı alan 97 hasta (grup 2) dahil edildi. Tüm olguların demografik, laboratuvar ve polisomnografik verileri retrospektif olarak gözden geçirildi. Bulgular: Yaş, cinsiyet, sigara ve alkol kullanımı açısından gruplar arasında anlamlı fark yoktu ancak kilo, boyun çevresi, bel çevresi ve vücut kitle indeksi istatistiksel olarak anlamlı ölçüde daha yüksek olarak saptandı (sırasıyla p=0,008, p=0,020, p=0,001, p=0,002). Ayrıca yine inceleme gecesinde ölçülen arteriyel diyastolik ve sistolik kan basınç değerleri ile total kolesterol, düşük yoğunluklu lipoprotein-kolesterol ve trigliserid değerlerinde gruplar arasında anlamlı fark olduğu ve Metabolik sendrom varlığının HBS grubunda belirgin olarak daha fazla gözlendiği saptandı (sırasıyla p=0,001, p=0,001, p=0,024, p=0,033, p=0,020, p=0,002). Sonuç: HBS hastalarında hipertansiyon, hiperlipidemi, obezite ve Metabolik sendrom sıklığı artmaktadır. HBS ve kardiyovasküler risk faktörleri arasındaki bu korelasyonun altında yatan potansiyel mekanizmaların aydınlatılması için daha fazla prospektif çalışmaya ihtiyaç duyulmaktadır.

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Cite This Article

AYDIN, Ş., ÖZDEMİR, C., SÖKÜCÜ, S. N. (2019). The Relationship Between Restless Legs Syndrome and Cardiovascular Risk Factors. Türk Uyku Tıbbı Dergisi, Cilt: 6 - Sayı: 2, 29–36. https://ajindex.com/articles/327932

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