Journals / Türk Yoğun Bakım Dergisi / 2020 / Cilt: 18 - Sayı: 2

Sepsis and Lipid Metabolism

Sepsis ve Lipit Metabolizması

Pages
63–69
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hypertriglyceridemia and hypocholesterolemia observed in sepsis is an expected response, such as an increase in fever and acute phase reactants, which are actually signs of acute inflammation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sepsis, as it is known, is frequently seen in intensive care units and may have high mortality and morbidity.
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Key Findings & Data:Sepsis causes significant changes in carbohydrate and protein metabolism, especially in lipid metabolism.
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Conclusion & Impact:Hypertriglyceridemia and hypocholesterolemia observed in sepsis is an expected response, such as an increase in fever and acute phase reactants, which are actually signs of acute inflammation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Sepsis, as it is known, is frequently seen in intensive care units and may have high mortality and morbidity. Sepsis causes significant changes in carbohydrate and protein metabolism, especially in lipid metabolism. It causes changes in chylomicrone, very low density lipoprotein, low density lipoprotein and high density lipoprotein levels, leading to hypertriglyceridemia and hypocholesterolemia in the foreground. This change in lipid metabolism also increases the risk of atherosclerosis. Hypertriglyceridemia and hypocholesterolemia observed in sepsis is an expected response, such as an increase in fever and acute phase reactants, which are actually signs of acute inflammation.

Özet

Sepsis, bilindiği üzere yoğun bakım ünitelerinde sık izlenmekle birlikte mortalite ve morbiditesi yüksek olabilmektedir. Sepsis, lipit metabolizması başta olmak üzere, karbonhidrat ve protein metabolizmasında önemli değişikliklere yol açmaktadır. Şilomikron, çok düşük dansiteli lipoprotein, düşük dansiteli lipoprotein ve yüksek dansiteli lipoprotein düzeyindeki değişikliklere bağlı olarak, ön planda hipertrigliseridemi ve hipokolesterolemi meydana gelmektedir. Lipit metabolizmasında gerçekleşen değişimler, ayrıca ateroskleroz riskini de artırmaktadır. Sepsiste gözlenen hipertrigliseridemi ve hipokolesterolemi, gerçekte akut enflamasyon bulguları olan ateş ve akut faz reaktanlarının artışı gibi beklenen bir yanıttır.

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Cite This Article

AKKER, M., UTKU, T. (2020). Sepsis and Lipid Metabolism. Türk Yoğun Bakım Dergisi, Cilt: 18 - Sayı: 2, 63–69. https://ajindex.com/articles/327677

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