Journals / Ulusal Cerrahi Dergisi / 2015 / Cilt: 31 - Sayı: 3

Anormal terminal ileum mukoza görüntüsü olanlarda terminal ileum biyopsisinin tanısal değeri

Diagnostic value of terminal ileum biopsies in patients with abnormal terminal ileum mucosal appearance

Pages
152–156
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Furthermore, in these patients, the macroscopic pathological diagnosis overlaps the histopathology, and it has a low diagnostic yield and lower clinical significance.

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Objective & Hypothesis:Objective: To investigate the necessity of obtaining routine ileal biopsy during colonoscopy in the patients with abnormal terminal ileum mucosal appearance if the inflammatory bowel disease is not considered.Material and Methods: A retrospective analysis was performed for 57 patients who were referred to a private hospital for colonoscopy between January 2008 and February 2009, in whom terminal ileum intubation was achieved and an abnormal appearance was observed.Results: There were 33 men and 24 women; the mean age was 44.12±11.42 years.
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Key Findings & Data:In 22 patients, the abnormality was ulcers and/or erosions.
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Conclusion & Impact:Furthermore, in these patients, the macroscopic pathological diagnosis overlaps the histopathology, and it has a low diagnostic yield and lower clinical significance.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate the necessity of obtaining routine ileal biopsy during colonoscopy in the patients with abnormal terminal ileum mucosal appearance if the inflammatory bowel disease is not considered.Material and Methods: A retrospective analysis was performed for 57 patients who were referred to a private hospital for colonoscopy between January 2008 and February 2009, in whom terminal ileum intubation was achieved and an abnormal appearance was observed.Results: There were 33 men and 24 women; the mean age was 44.12±11.42 years. In 22 patients, the abnormality was ulcers and/or erosions. In 10 patients, there were mucosal nodularity and in 24, the finding was erythema. The time to reach to ileum from cecum was 28.78±24.30 s. The mean length of the examined ileum was 12.93±6.05 cm. There was no difference between groups according to distance covered in the ileum for diagnostic yield, but going further than 2 cm was important.Conclusion: There should be no need to obtain routine biopsy in patients with abnormal terminal ileum mucosa appearance, when inflammatory bowel disease is not considered. In these patients, histopathology also reveals nonspecific ileitis. Furthermore, in these patients, the macroscopic pathological diagnosis overlaps the histopathology, and it has a low diagnostic yield and lower clinical significance.

Özet

Amaç: Anormal terminal ileum mukoza görünümüne sahip hastalarda, enflamatuvar barsak hastalığı düşünülmüyorsa, kolonoskopi esnasında rutin ileum biopsisi almanın gerekliliğini araştırmak.Gereç ve Yöntemler: Ocak 2008 ile Şubat 2009 tarihleri arasında kolonoskopi amacıyla özel bir merkeze yönlendirilen, terminal ileum entubasyonu yapılıp anormal görünüm tespit edilen 57 hastanın retrospektif değerlendirilmesi yapıldı.Bulgular: Ortalama yaşları 44,12±11,42 olan 33 erkek ve 24 kadın hasta mevcuttu. Bunların 22'sinde anormal bulgu, ülser ya da erezyonlardı. 10 hastada mukozal nodülarite, 24 hastada eritem mevcuttu. Çekumdan ileuma ulaşma süresi 28,78±24,30 saniye idi. İncelenen ortalama ileum uzunluğu 12,93±6,05 cm idi. Tanı konulması için ileumda katedilen mesafe açısından gruplar arasında istatistiki olarak anlamlı farklılık yokken 2 cm'den daha uzağa gitmek anlamlıydı.Sonuç: Anormal terminal ileum mukozal görünümü olan fakat enflamatuvar bağırsak hastalığı düşünülmeyen hastalarda rutin biyopsi alınmasına gerek yoktur. Çünkü bu hastalarda histopataoloji non-spesifik ileit olarak gelmektedir. Bu hastalarda makroskopik patolojik tanı histopatoloji ile uyuşmakta ve düşük tanısal ve klinik değer taşımaktadır.

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Cite This Article

VELİDEDEOĞLU, M., ARIKAN, A. E., ZENGİN, A. K. (2015). Anormal terminal ileum mukoza görüntüsü olanlarda terminal ileum biyopsisinin tanısal değeri. Ulusal Cerrahi Dergisi, Cilt: 31 - Sayı: 3, 152–156. https://ajindex.com/articles/325625

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