Pulmonary alveolar microlithiasis (A case report)

Objective & Hypothesis:Pulmonary alveolar microlithiasis is a rare disease characterised by deposition of calcium phosphate concretions within alveolar air spaces.

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Key Findings & Data:A 25-year-old female admitted with dry cough and mild dyspnea on exertion complaints for three weeks.

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Conclusion & Impact:We were following the patient for 1.5 years and she has not any complaint other than mild exercise intolerance now.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Erişkin · Tomografi · x-ışınlı bilgisayarlı

Abstract

Pulmonary alveolar microlithiasis is a rare disease characterised by deposition of calcium phosphate concretions within alveolar air spaces. A 25-year-old female admitted with dry cough and mild dyspnea on exertion complaints for three weeks. There was not history related to microlithiasis in her relatives. Physical examination was unrevealing. Innumerous very fine micronodular opacities diffusely involved both lungs were seen in her chest radiographs. The opacities were more prominent in lower lung fields. Spirometry was normal and DLCO was mildly decreased. There was not hypoxemia in her arterial blood gases and alveolar-arterial O>2 difference was in normal range. The bronchial tree was apparent normal in fiberoptic bronchoscopic examination and we performed transbronchial biopsy. Result of histopathologic study of this biopsy shown that typical concentric calcified structures obliterated alveolar spaces. We were following the patient for 1.5 years and she has not any complaint other than mild exercise intolerance now.

Özet

Pulmoner alveoler mikrolitiazis alveol boşluklarında kalsiyum fosfat çökeltilerinin birikimi ile karakterize nadir bir hastalıktır. Yirmibeş yaşında bayan hasta 3 haftadır kuru öksürük ve eforla hafif nefes darlığı yakınmaları ile başvurdu. Akrabalarında mikrolitiazis bulgusuna rastlanmadı. Fizik muayenesinde belirgin anormallik saptanmadı. Akciğer grafilerinde özellikle alt zonlarda bilateral yaygın çok sayıda mikronodüler opasiteler bulunduğu görüldü. Spirometri normal ve DLCO hafif azalmış bulundu. Arteryel kan gazı tetkikinde hipoksemi saptanmadı; alveolo-arteryel O2 farkı normal sınırlardaydı. Fiberoptik bronkoskopide bronşlar doğal izlendi. Transbronşiyal biyopsi materyalinde alveol boşluklarını dolduran tipik konsantrik kalsifiye yapılar görüldü. Hasta 1.5 yıldır izleniyor ve şu anda hafif egzersiz intoleransı dışında yakınması bulunmuyor.

Keywords

Erişkin Tomografi x-ışınlı bilgisayarlı Lityazis Akciğer hastalıkları Pulmoner alveol Adult Tomography X-Ray Computed Lithiasis Lung Diseases Pulmonary Alveoli

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Cite This Article

BERKTAŞ, M. B., BAŞAY, N., ÖZDEMİR, T., MUTLUAY, İ. N., BAYIZ, H., BERKOĞLU, M. (2002). Pulmonary alveolar microlithiasis (A case report). Solunum Hastalıkları, Cilt: 13 - Sayı: 4, 303–306. https://ajindex.com/articles/318680

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