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Journals / Records of Natural Products / 2017 / Cilt: 11 - Sayı: 3

Phytochemical Studies and Antioxidant Activities of Artocarpus scortechinii King

Norzafneza Mohd ARRİFFİN
Shajarahtunnur JAMİL
Norazah BASAR
Siti Awanis ABDULLAH
Siti Mariam Abdul LATHİFF
Pages
299–336
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Luteolin (9) also exhibited the strongest scavenger and potent ferric ion reducer compared to other isolated compounds in the ABTS and FRAP assays with IC50 value of 124.4µM and 4.07 ± 0.180 mM FRAP equivalent respectively

📌 3 Key Takeaways

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Objective & Hypothesis:Six known compounds identified as 4',5-dihydroxy-6,7-(2,2-dimethylpyrano)-2'-methoxy-8-γ,γdimethylallyflavone (1), cudraflavone A (2), artocarpin (3), cycloartobiloxanthone (4), artonin E (5) and oxyresveratrol (6) were isolated from the stem barks of Artocapus scortechinii King.
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Key Findings & Data:Another four compounds namely macakurzin C (7), flemichapparin A (8), luteolin (9) and apigenin (10) were isolated from the leaves.
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Conclusion & Impact:Luteolin (9) also exhibited the strongest scavenger and potent ferric ion reducer compared to other isolated compounds in the ABTS and FRAP assays with IC50 value of 124.4µM and 4.07 ± 0.180 mM FRAP equivalent respectively
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Six known compounds identified as 4',5-dihydroxy-6,7-(2,2-dimethylpyrano)-2'-methoxy-8-γ,γdimethylallyflavone (1), cudraflavone A (2), artocarpin (3), cycloartobiloxanthone (4), artonin E (5) and oxyresveratrol (6) were isolated from the stem barks of Artocapus scortechinii King. Another four compounds namely macakurzin C (7), flemichapparin A (8), luteolin (9) and apigenin (10) were isolated from the leaves. Structures of all pure compounds were elucidated spectroscopically using 1D NMR (1H, 13C, DEPT), 2D NMR (COSY, HMQC, HMBC), MS and FTIR, as well as by comparison with literature data. All isolated compounds were evaluated for their antioxidant capacities using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3ethylbenzthiazoline-6-sulphonic acid) (ABTS) and ferric reducing antioxidant potential (FRAP) assays. Luteolin (9) showed the best ability to act as DPPH free radical scavenger with IC50 value of 9.51 µM. Luteolin (9) also exhibited the strongest scavenger and potent ferric ion reducer compared to other isolated compounds in the ABTS and FRAP assays with IC50 value of 124.4µM and 4.07 ± 0.180 mM FRAP equivalent respectively

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Cite This Article

ARRİFFİN, N. M., JAMİL, S., BASAR, N., ABDULLAH, S. A., LATHİFF, S. M. A. (2017). Phytochemical Studies and Antioxidant Activities of Artocarpus scortechinii King. Records of Natural Products, Cilt: 11 - Sayı: 3, 299–336. https://ajindex.com/articles/308638

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