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Journals / Records of Natural Products / 2018 / Cilt: 12 - Sayı: 3

Effects of Olea europaea L. Leaf Metabolites on the Tilapia (Oreochromis niloticus) and Three Stored Pests, Sitophilus granarius, Tribolium confusum and Acanthoscelides obtectus

Ahmet KISA
MEHMET AKYÜZ
HİKMET YETER ÇOĞUN
Şaban KORDALİ
AYŞE USANMAZ BOZHÜYÜK
Binnur TEZEL
Umran ŞİLTELİOĞLU
BARIŞ ANIL
AHMET ÇAKIR
Pages
201–221
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results suggested that the compounds tested affect the liver metabolism of Nile tilapia.

📌 3 Key Takeaways

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Objective & Hypothesis:Olea europea L. emerged as a good source of traditional medicine for the treatment of various ailments of various countries of the world, in particular Mediterranean countries.
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Key Findings & Data:In this study, oleuropein (1), oleanolic acid (2), maslinic acid (3), a mixture of erythrodiol and uvaol (4 and 5) isolated from the leaves of olive were added at two concentrations (1g/100g feed and 4g/100 g feed) into fish feed.
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Conclusion & Impact:These results suggested that the compounds tested affect the liver metabolism of Nile tilapia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Olea europea L. emerged as a good source of traditional medicine for the treatment of various ailments of various countries of the world, in particular Mediterranean countries. In this study, oleuropein (1), oleanolic acid (2), maslinic acid (3), a mixture of erythrodiol and uvaol (4 and 5) isolated from the leaves of olive were added at two concentrations (1g/100g feed and 4g/100 g feed) into fish feed. Oreochromis niloticus (Nile tilapia) were fed twice a day with the feed during 96 hours. The levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) enzymes and glucose levels in the serums of fishes fed with pure compounds were found to be higher as compared with the control group. Pure metabolites affect the liver metabolism of Nile tilapia. These results suggested that the compounds tested affect the liver metabolism of Nile tilapia. Compounds 1, 2, 3 and 4+5 (2.5, 5.0 and 7.5 mg/Petri dish concentrations) were also tested for contact toxic effects against three important stored pests, Sitophilus granarius (weevil), Tribolium confusum (confused flour beetle) and Acanthoscelides obtectus (bean weevil). The toxic effects of the metabolites were lower than those of the insecticide, dichlorvos (DDVP). DDVP caused complete mortality of the insects after 48 hours of treatments, the metabolites caused the mortality rates 16.7-63.3 %, 13.3-67.0 % and 26.7-59.0 % of S. granarius, T. confusum and A. obtectus, respectively. Maslinic acid (3) has the most toxic compound with the lowest LC50 values (0.66 mg/Petri, 0.61 mg/Petri and 1.71 mg/Petri for S. granarius, T. confusum and A. obtectus, respectively). These results show that maslinic acid (3) as well as other substances can be used as natural insecticides against these pests

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Cite This Article

KISA, A., AKYÜZ, M., ÇOĞUN, H. Y., KORDALİ, Ş., BOZHÜYÜK, A. U., TEZEL, B., ŞİLTELİOĞLU, U., ANIL, B., ÇAKIR, A. (2018). Effects of Olea europaea L. Leaf Metabolites on the Tilapia (Oreochromis niloticus) and Three Stored Pests, Sitophilus granarius, Tribolium confusum and Acanthoscelides obtectus. Records of Natural Products, Cilt: 12 - Sayı: 3, 201–221. https://ajindex.com/articles/308298

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References (9)

  1. H. W. Zhang, Y. F. Tang, C. F. Ruan and X. L. Bai (2016). Bioactive secondary metabolites from the endophytic Aspergillus genus, Rec. Nat. Prod. 10, 1-16.
  2. J. C. Frisvad and T.O. Larsen (2015). Chemodiversity in the genus Aspergillus, Appl. Microbiol. Biotechnol. 99, 7859–7877.
  3. A. M. Hill, A. Jacobs and J. Staunton (1995). Investigation of the stereochemistry of the tri- and tetraketide hydroxyacyl intermediates in the biosynthesis of the polyketide aspyrone in Aspergillus malleus using deuterium labelling and deuterium NMR spectroscopy, J. Chem. Soc. Chem. Commun. 8, 859-860.
  4. H. Zhou, L. X. Zhao, W. Li, Y. B. Yang, L. H. Xu, and Z. T. Ding (2015). Anti-Mycobacterium tuberculosis active metabolites from an endophytic Streptomyces sp. YIM65484, Rec. Nat. Prod. 9, 196-200.
  5. X. W. Chen, C. W. Li, C. B. Cui, W. Hua, T.J. Zhu and Q. Q. Gu (2014) Nine new and five known polyketides derived from a deep sea-sourced Aspergillus sp. 16-02-1, Mar. Drugs 12, 3116-3137.
  6. K. Kito, R. Ookura, S. Yoshida, M. Namikoshi, T. Ooi and T. Kusumi (2007). Pentaketides relating to aspinonene and dihydroaspyrone from a marine-derived fungus, Aspergillus ostianus, J. Nat. Prod. 70, 2022–2025.
  7. Y. Y. Li, P. Liu, Y. Tang, H. M. Li, Y. L. Tang, X. H. Liang and Y. J. Tang (2013). Novel cerebrosides isolated from the fermentation mycelia of Tuber indicum, Helv. Chim. Acta 96, 702-709.
  8. W. Li, X. Q. Yang, Y. B. Yang, S. H. Qin, Q. L. Li, L. X. Zhao and Z. T. Ding (2015). A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp., Nat. Prod. Res. 29, 132– 136. [9] N. Kamal, C. V. Viegelmann, C. J. Clements and R. A. Edrada-Ebel. Metabolomics-guided isolation of antitrypanosomal metabolites from the endophytic fungus Lasiodiplodia theobromae, Planta Med. DOI: 10.1055/s-0042-118601.
  9. C. H. Lu, S. S. Liu, J. Y. Wang, M. Z. Wang and Y. M. Shen (2014). Characterization of eight new secondary metabolites from the mutant strain G-444 of Tubercularia sp. TF5, Helv. Chim. Acta, 97, 334- 344.