Journals / Records of Natural Products / 2018 / Cilt: 12 - Sayı: 2

An Overview on the Role of Macular Xanthophylls in Ocular Diseases

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1–14
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this review is to evaluate the relationship between the consumption of lutein and zeaxanthin and eye diseases.

📌 3 Key Takeaways

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Objective & Hypothesis:Macula lutea, is the center of the retina of the eye, contains high concentrations of lutein and zeaxanthin which can act as a filter against short-wavelength (blue) light.
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Key Findings & Data:Lutein and zeaxanthin are the only carotenoids detected in human lens which exhibit highly strong free radical scavenging activity.
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Conclusion & Impact:The aim of this review is to evaluate the relationship between the consumption of lutein and zeaxanthin and eye diseases.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Macula lutea, is the center of the retina of the eye, contains high concentrations of lutein and zeaxanthin which can act as a filter against short-wavelength (blue) light. Lutein and zeaxanthin are the only carotenoids detected in human lens which exhibit highly strong free radical scavenging activity. Many epidemiological studies, clinical trials, animal experiments have suggested that lutein and zeaxanthin have antiinflammatory potential with their high antioxidant properties. Several eye diseases including, age-related macular degeneration, uveitis and retinitis pigmentosa are caused by ocular inflammation. Some studies have shown that lutein and zeaxanthin could be protective, curative and preventive against ocular inflammation induced diseases and other ocular disorders such as cataract, glaucoma and choroideremia. The mechanisms responsible for these effects are absorption of near-ultraviolet and blue light, reduction of oxidative stress, inflammation and angiogenesis. Lutein and zeaxanthin can be taken from dietary supplements or a diet high in fruits, vegetables such as kale, spinach and turnip greens. The aim of this review is to evaluate the relationship between the consumption of lutein and zeaxanthin and eye diseases.

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Cite This Article

YILMAZ, S. S., ÇOBAN, T. (2018). An Overview on the Role of Macular Xanthophylls in Ocular Diseases. Records of Natural Products, Cilt: 12 - Sayı: 2, 1–14. https://ajindex.com/articles/308273

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