Journals / Records of Natural Products / 2020 / Cilt: 14 - Sayı: 4

Two New Compounds from the Deep-Sea-Derived Fungus Aspergillus sp. YPGA8

Pages
307–311
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The bioassay study revealed that compounds 1 and 2 were inactive toward -glucosidase.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Chemical examination of a fraction of the EtOAc extract of a marine-derived fungus Aspergillus sp.
📊
Key Findings & Data:YPGA8 resulted in the isolation of two new compounds, namely aspertriols AB (12).
💡
Conclusion & Impact:The bioassay study revealed that compounds 1 and 2 were inactive toward -glucosidase.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Chemical examination of a fraction of the EtOAc extract of a marine-derived fungus Aspergillus sp. YPGA8 resulted in the isolation of two new compounds, namely aspertriols AB (12). Compounds 12 possess an identical 2,3,4-trihydroxybutoxy moiety, which is rarely found in natural products. Their structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, HRESIMS). The bioassay study revealed that compounds 1 and 2 were inactive toward -glucosidase.

🔖

Cite This Article

PAN, M., TİAN, Z., YANG, H., XU, W., PAN, C., CHENG, Z., Lİ, Q. (2020). Two New Compounds from the Deep-Sea-Derived Fungus Aspergillus sp. YPGA8. Records of Natural Products, Cilt: 14 - Sayı: 4, 307–311. https://ajindex.com/articles/308206

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Z. Cheng, Y. Li, W. Liu, L. Liu, J. Liu, W. Yuan, Z. Luo, W. Xu and Q. Li (2019). Butenolide derivatives with α-glucosidase inhibitions from the deep-sea-derived fungus Aspergillus terreus YPGA10, Mar. Drugs 17, 332 (9 pages)
  2. Y. L. Li, W. Liu, W. Xu, X. Zeng, Z. B. Cheng and Q. Li (2020). Aspterrics A and B, new sesquiterpenes from deep sea-derived fungus Aspergillus terreus YPGA10, Rec. Nat. Prod. 14, 18-22
  3. K. Nakanishi, M. Doi, Y. Usami, T. Amagata, K. Minoura, R. Tanaka, A. Numata and T. Yamada (2013). Anthcolorins A-F, novel cytotoxic metabolites from a sea urchin-derived Aspergillus versicolor, Tetrahedron 69, 4617-4623
  4. X. Liang, X. Zhang, X. Lu, Z. Zheng, X. Ma and S. Qi (2019). Diketopiperazine-type alkaloids from a deep-sea-derived Aspergillus puniceus fungus and their effects on liver X receptor α, J Nat. Prod. 82, 1558-1564
  5. J. Peng, H. Gao, X. Zhang, S. Wang, C. Wu, Q. Gu, P. Guo, T. Zhu and D. Li (2014). Psychrophilins EH and versicotide C, cyclic peptides from the marine-derived fungus Aspergillus versicolor ZLN-60, J. Nat. Prod. 77, 2218-2223
  6. Y. Sun, J. Liu, L. Li, C. Gong, S. Wang, F. Yang, H. Hua and H. Lin (2018). New butenolide derivatives from the marine sponge-derived fungus Aspergillus terreus, Bioorg. Med. Chem. Lett. 28, 315-318
  7. F.D. Kong, X.L. Huang, Q.Y. Ma, Q.Y. Xie, P. Wang, P.W. Chen, L.M. Zhou, J.Z. Yuan, H.F. Dai, D.Q. Luo and Y.X. Zhao (2018). Helvolic acid derivatives with antibacterial activities against Streptococcus agalactiae from the marine-derived fungus Aspergillus fumigatus HNMF0047, J. Nat. Prod. 81, 1869- 1876
  8. Y. Tan, B. Yang, X. Lin, X. Luo, X. Pang, L. Tang, Y. Liu, X. Li and X. Zhou (2018). Nitrobenzoyl sesquiterpenoids with cytotoxic activities from a marine-derived Aspergillus ochraceus fungus, J. Nat. Prod. 81, 92-97
  9. Y. Wu, Y. Chen, X. Huang, Y. Pan, Z. Liu, T. Yan, W. Cao and Z. She (2018). α-Glucosidase inhibitors: diphenyl ethers and phenolic bisabolane sesquiterpenoids from the mangrove endophytic fungus Aspergillus flavus QQSG-3, Mar. Drugs 16, 307
  10. Q. Wang, X.Q. Yang, C.P. Miao, L.H. Xu, Z.T. Ding, Y.B. Yang and L.X. Zhao (2018). A new pair of pentaketide diastereoisomers from Aspergillus melleus YIM PHI001, Rec. Nat. Prod. 12, 216-221
  11. S. Jibril, H. Mohd Sirat and N. Basar (2017). Bioassay-guided isolation of antioxidants and αglucosidase inhibitors from the root of Cassia sieberiana D.C. (Fabaceae), Rec. Nat. Prod. 11, 406-410
  12. J.-F. Basset, C.