Journals / Retina-Vitreus / 2015 / Cilt: 23 - Sayı: 2

Evaluation of Retinal Nerve Fiber Thickness By Optic Coherens Tomography in Smokers

Sigara İçenlerde Retinal Sinir Lifi Kalınlığının Optik Koherens Tomografi ile Değerlendirilmesi

Pages
137–140
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is advisable that heavy smokers should be cautioned for such a possible correlation and regularly followed-up

📌 3 Key Takeaways

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Objective & Hypothesis:To investigate whether smoking cause any changes in number of ganglion cells, ganglion cell layer thickness and optic nerve head in healthy adults.Material and Methods: In the study volunteers aged from 20 to 50 who admitted to ophthalmology department of Mustafa Kemal University Faculty of Medicine between April 2013 and October 2013 were included; of which 73 were non smoker and 78 were smokers.
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Key Findings & Data:SPSS for Windows 13, 0 (Statistical Package for Social Sciences) was used for statistical analysis.Results: Upper quadrant thickness was 122.41±14.43 ?m in smokers and was 118.77±17.89 ?m in non smokers.
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Conclusion & Impact:It is advisable that heavy smokers should be cautioned for such a possible correlation and regularly followed-up
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

To investigate whether smoking cause any changes in number of ganglion cells, ganglion cell layer thickness and optic nerve head in healthy adults.Material and Methods: In the study volunteers aged from 20 to 50 who admitted to ophthalmology department of Mustafa Kemal University Faculty of Medicine between April 2013 and October 2013 were included; of which 73 were non smoker and 78 were smokers. Retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (Cirrus HD OCT); fast RNFL protocol was used. SPSS for Windows 13, 0 (Statistical Package for Social Sciences) was used for statistical analysis.Results: Upper quadrant thickness was 122.41±14.43 ?m in smokers and was 118.77±17.89 ?m in non smokers. Nasal quadrant thickness was 75.07±12.53 ?m in smokers and was 76.68±15.00 ?m in non smokers, lower quadrant thickness was 125.40±19.97 ?m in smokers and was 127.85±17.58 ?m in non smokers; there was no statistically significant difference in these groups. Temporal quadrant thickness was 68.10±9.74 ?m in smokers and was 72.40±10.80 ?m in non smokers and the difference was statistically significant. Upper, nasal, inferior, temporal quadrants and average RNFL values showed no statistically significant difference between mild, moderate or severe smokers subgroups.Conclusion: The study implies thinning of temporal quadrant RNFL thickness in smokers. This is likely to occur due to neurotoxic damage caused by smoking. It is advisable that heavy smokers should be cautioned for such a possible correlation and regularly followed-up

Özet

Sigaranın sağlıklı erişkinlerde optik sinir başı retinal ganglion hücre tabaka kalınlığı ve ganglion hücre sayısında değişikliğe yol açıp açmadığının araştırılması.Gereç ve Yöntem: Çalışma kapsamına Nisan 2013-Ekim 2013 tarihleri arasında Mustafa Kemal Üniversitesi Tıp Fakültesi Göz Hastalıkları Polikliniğine başvuran 20-50 yaş arası hastalar arasından sigara içen 73 gönüllü ile sigara içmeyen 78 gönüllü çalışmaya dâhil edilmiştir. Retina sinir lifi kalınlığı (RSLK) ölçümünde optik koherens tomografi (Cirrus HD OKT); Fast RNFL protokolü kullanılmıştır. İstatistiksel değerlendirmeler için SPSS for Windows 13,0 (Statistical Package for Socl Sciences) paket programı kullanıldı.Bulgular: Üst kadran kalınlığı sigara içenlerde 122.41±14.43 ?m içmeyenlerde ise 118.77±17.89 ?m; nazal kadran kalınlıkları sigara içenlerde 75.07±12.53 ?m içmeyenlerde 76.68±15.00 ?m; alt kadran kalınlıkları sigara içenlerde 125.40±19.97 ?m içmeyenlerde 127.85±17.58 ?m bulunmuş olup bu kadranlarda görülen farklar istatistiksel olarak anlamlı bulunmamıştır. Temporal kadran kalınlıkları ise sigara içenlerde 68.10±9.74 ?m içmeyenlerde ise 72.40±10.80 ?m olarak saptanmış olup iki grup arasında anlamlı fark olduğu görülmüştür. Üst, nazal, alt ve temporal kadran ile ortalama RSLK değerlerine bakıldığında hafif içici, orta içici ve ağır içici alt grupları arasında istatistiksel olarak anlamlı fark saptanmamıştır. Sonuç: Sigara içen ve içmeyen gruplar arasında sadece optik diskin temporal kadranında RSLK kalınlığı arasında anlamlı fark saptandı. Sigara nörotoksik etkisi ile sinir lifinde hasar oluşturabilir. Sigara içenlerin en azından belli aralıklarla RSLK kalınlıklarının OKT ile takibi önerilebilir

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Cite This Article

AKARSU, M., ABİT, M. S., İLHAN, Ö. (2015). Evaluation of Retinal Nerve Fiber Thickness By Optic Coherens Tomography in Smokers. Retina-Vitreus, Cilt: 23 - Sayı: 2, 137–140. https://ajindex.com/articles/307901

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