Journals / Retina-Vitreus / 2015 / Cilt: 23 - Sayı: 3

Bilateral Vitreomacular Traction Syndrome Secondary to An Aromatase Inhibitor Usage

Aromataz İnhibitörü Kullananımına Bağlı Bilateral Vitreomaküler Traksiyon Sendromu

Pages
255–258
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report a 56- years-old woman with bilateral vitreomacular traction sydrome treated with anastrozole more than two years to decrease recurrence of breast cancer

📌 3 Key Takeaways

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Objective & Hypothesis:The selective third-generation aromatase inhibitors (anastrozole, letrozole, and exemestane ) have been used for more than ten years in worldwide for the standard of therapy for hormone-receptor-positive breast cancer in postmenopausal women.
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Key Findings & Data:Based on analysis of OCT retinal thickness data, it is likely that aromatase inhibitors increases the tractional force between the vitreous and retina, and this might be at increased risk for traction-related vision loss.
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Conclusion & Impact:We report a 56- years-old woman with bilateral vitreomacular traction sydrome treated with anastrozole more than two years to decrease recurrence of breast cancer
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The selective third-generation aromatase inhibitors (anastrozole, letrozole, and exemestane ) have been used for more than ten years in worldwide for the standard of therapy for hormone-receptor-positive breast cancer in postmenopausal women. The authors are in agreement on the effectiveness of this drug in breast cancer, but the type and number of side effects have been quite variable. Based on analysis of OCT retinal thickness data, it is likely that aromatase inhibitors increases the tractional force between the vitreous and retina, and this might be at increased risk for traction-related vision loss. We report a 56- years-old woman with bilateral vitreomacular traction sydrome treated with anastrozole more than two years to decrease recurrence of breast cancer

Özet

Selektif üçüncü kuşak aromataz inhibitörleri (anastrozol, letrozol ve eksemestan) on yılı aşkın bir süredir menopoz sonrası dönmede olan, hormon reseptörü pozitif (HR+) meme kanserli olguların tedavisinde kullanılmaktadır. İlacın meme kanseri üzerinde olan etkinliği genel olarak kabul görse de yan etkilerinin tipleri ve sayısı oldukça değişkenlik gösterebilmektedir. Aromataz inhibitörü kullanan hastaların Optik Kohorens Tomografi (OKT) ile yapılan retinal kalınlık analizlerinde vitrues ile retina arasındaki traksiyonel kuvvetin arttığı ve bunun görmeyi tehdit edebileceği ortaya konmuştur. Bu sunumda meme kanserinin nüksünü azaltmak için iki yılı aşkın süredir anastrozol kullanan ve bunun neticesinde her iki gözünde vitreomaküler traksiyon sendromu tespit edilen 56 yaşındaki bir bayan hastayı literatür eşliğinde sunmak istedik

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Cite This Article

ELİAÇIK, M., ERDUR, S. K., GÜLKILIK, G. (2015). Bilateral Vitreomacular Traction Syndrome Secondary to An Aromatase Inhibitor Usage. Retina-Vitreus, Cilt: 23 - Sayı: 3, 255–258. https://ajindex.com/articles/307646

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