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Journals / Retina-Vitreus / 2016 / Cilt: 24 - Sayı: 4

Waldenström Makroglobulinemi'li Bir Olguda Bilateral Seröz Makula Dekolmanı ve Unilateral Koroidal Neovasküler Membran Birlikteliği

Bilateral Serous Macular Detachment and Unilateral Choroidal Neovascular Membrane in a Patient With Waldenström's Macroglobulinemia

Önder AYYILDIZ
A. Hakan DURUKAN
GÖKHAN ÖZGE
Murat KÜÇÜKEVCİLİOĞLU
Dorukcan AKINCIOĞLU
Seçkin AYKAŞ
Pages
330–332
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We describe the first case of WM with bilateral SMD associated unilateral CNVM in our knowledge who was treated with plasmapheresis and IVR.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 74-year-old male with hyperviscosity due to Waldenström's macroglobulinemia (WM) presented with bilateral decreased vision.
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Key Findings & Data:Optical coherence tomography revealed the complete resolution of SMD, and also the presence of CNVM with a central foveal thickness of 308 micron.
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Conclusion & Impact:We describe the first case of WM with bilateral SMD associated unilateral CNVM in our knowledge who was treated with plasmapheresis and IVR.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 74-year-old male with hyperviscosity due to Waldenström's macroglobulinemia (WM) presented with bilateral decreased vision. Bilateral serous macular detachment (SMD) was observed in fundoscopy. Optical coherence tomography (OCT) confirmed bilateral SMD, which was associated with choroidal neovascular membrane (CNVM) in the left eye (LE). The patient received plasmapheresis due to hyperviscosity. He experienced visual improvement in the right eye (RE) shortly after the plasmapheresis. However, there was not any visual improvement in the LE three months after the plasmapheresis. Optical coherence tomography revealed the complete resolution of SMD, and also the presence of CNVM with a central foveal thickness of 308 micron. The patient recieved three doses of intravitreal ranibizumab (IVR) injections monthly to treat CNVM in the LE, which later showed no visual and anatomical improvement. We describe the first case of WM with bilateral SMD associated unilateral CNVM in our knowledge who was treated with plasmapheresis and IVR.

Özet

Waldenström makroglobulinemiye (WM) bağlı hipervisközite bulunan 74 yaşında erkek bir hasta bilateral görme azlığı ile başvurdu. Fundoskopide bilateral seröz makula dekolmanı (SMD) gözlendi. Optik koherens tomografi (OKT), sol gözde koroidal neovasküler membran (KNVM) ile ilişkili olan bilateral SMD varlığını gösterdi. Hastaya hipervizkozite nedeniyle plazmaferez uygulandı. Plazmaferezden hemen sonra sağ gözde görme düzeyinde artış oldu. Fakat, plazmaferezden üç ay geçmesine rağmen sol gözde görme artışı olmadı. Optik koherens tomografi sol gözde SMD'nin tam rezolüsyonunu ve aynı zamanda KNVM ile birlikte merkezi foveal kalınlığın 308 mikron olduğunu gösterdi. Sol gözündeki KNVM'yi tedavi etmek amacıyla hastaya üç doz intravitreal ranibizumab (IVR) aylık uygulandı, fakat görsel ve anatomik düzelme sağlanamadı. Plazmaferez ve IVR ile tedavi edilmiş, unilateral KNVM ile ilişkili iki gözünde SMD tespit edilen bildiğimiz kadarıyla ilk WM'li vakayı tanımlıyoruz.

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Cite This Article

AYYILDIZ, Ö., DURUKAN, A. H., ÖZGE, G., KÜÇÜKEVCİLİOĞLU, M., AKINCIOĞLU, D., AYKAŞ, S. (2016). Waldenström Makroglobulinemi'li Bir Olguda Bilateral Seröz Makula Dekolmanı ve Unilateral Koroidal Neovasküler Membran Birlikteliği. Retina-Vitreus, Cilt: 24 - Sayı: 4, 330–332. https://ajindex.com/articles/306937

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