Journals / Romatizma Dergisi / 2003 / Cilt: 18 - Sayı: 2

Metabolic, endocrin and socio-cultural risk factors in patients with primary osteoarthritis of the knee and relationship with radiological findings

Primer diz osteoartritinde metabolik, endokrin ve sosyo-kültürel risk faktörleri ve radyolojik bulgularla ilişkisi

Pages
92–98
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, weight, distrubiton of fat tissue, sedentary life style, some metabolic factors and systemic diseases were determined to be the risk factors for knee osteoarthritis.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to investigate some of the risk factors associated with osteoarthritis of the knee and the relationship of these risk factors with radiographic findings.
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Key Findings & Data:Weight, body mass index, diabetes mellitus, hypertension, serum glucose and uric acid levels and sedentary life style were significantly higher when compared with healthy controls.
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Conclusion & Impact:In conclusion, weight, distrubiton of fat tissue, sedentary life style, some metabolic factors and systemic diseases were determined to be the risk factors for knee osteoarthritis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Vücut bileşenleri · Antropometri · Osteoartrit

Abstract

The aim of this study was to investigate some of the risk factors associated with osteoarthritis of the knee and the relationship of these risk factors with radiographic findings. One hundred patients with no known metabolic or inflammatory articular diseases who had a clinical and radiological diagnosis of knee osteoarthritis, and eighteen sex and age matched healthy controls were included in this study. All patients and controls were questioned for accompanying systemic diseases, life style and daily life habits. All patients had undergone physical examination and anthropometric measures were (height, weight, subcutaneous fat tissue) determined. The laboratory parameters like serum glucose, uric acid, lipids, calcium, phosphorus, alkaline phosphotase levels were measured. Radiographic findings were assessed by using the method of Kellegren Lawrence. Weight, body mass index, diabetes mellitus, hypertension, serum glucose and uric acid levels and sedentary life style were significantly higher when compared with healthy controls. A positive correlation was observed between the age, pain, post menopousal duration and centrality ratio and Kellegren Lawrence radiological scores. In conclusion, weight, distrubiton of fat tissue, sedentary life style, some metabolic factors and systemic diseases were determined to be the risk factors for knee osteoarthritis. Determination of modifiable risk factors and avoidance of them may help to decrease the incidence and severity of knee osteoarthritis.

Özet

Bu çalışmanın amacı; çeşitli risk faktörleri ile diz osteoartriti arasındaki ve bu risk faktörleri ile radyolojik bulgular arasındaki ilişkiyi araştırmaktır. Çalışmaya metabolik veya inflamatuvar eklem hastalığı olmayan, klinik ve radyolojik olarak diz osteoartriti tanısı konulan 100 olgu ve karşılaştırma için yaş ve cinsiyeti benzer 18 sağlıklı kontrol alındı. Tüm olgular eşlik eden sistemik hastalıklar, yaşam tarzları ve alışkanlıkları açısından sorgulandı. Hastalara tam bir fizik muayene yapıldı ve antropometrik ölçümleri (boy, kilo, cilt altı yağ dokusu ölçümü) kaydedildi. Laboratuvar incelemelerde serum glikoz, ürik asit, lipid profili, kalsiyum, fosfor, alkalen fosfataz düzeylerine bakıldı. Diz eklemi direkt radyolojik görüntüleri ise Kellgren-Lawrence metoduna göre değerlendirildi. Çalışma ve kontrol grubu arasında yapılan karşılaştırmalarda, osteoartritli hasta grubunda vücut ağırlığı, vücut kitle indeksi, diabetes mellitus, hipertansiyon ve serum glikoz, ürik asit seviyeleri ve sedanteryaşam tarzı kontrol grubundan anlamlı derecede yüksek bulundu. Kellegren-Lawrence radyolojik skoru ile ise yaş, ağrı süresi, postmenopozal süre ve santralite oranı arasında pozitif korelasyon saptandı. Sonuç olarak bu çalışmada vücut ağırlığı, yağ dokusu dağılımı, sedanter yaşam tarzı, bazı metabolik faktörler ve sistemik hastalıklar risk faktörleri olarak belirlenmiştir. Değiştirilebilir risk faktörlerinin tespiti ve önlenmesi diz osteoartriti insidansını ve şiddetini azaltabilir.

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Cite This Article

SAMANCI, N., KAÇAR, C., SAYIN, M., TUNCER, T. (2003). Metabolic, endocrin and socio-cultural risk factors in patients with primary osteoarthritis of the knee and relationship with radiological findings. Romatizma Dergisi, Cilt: 18 - Sayı: 2, 92–98. https://ajindex.com/articles/306173

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