SavedAdd your journal

Journals / Retina-Vitreus / 2013 / Cilt: 21 - Sayı: 4

Retinopathy of prematurity

Prematüre retinopatisi

Berrin UZUNOVALI
Ayşe ÖNER ÖZTÜRK
Pages
314–319
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review we discuss risk factors, epidemiology, pathogenesis, screening and management of ROP

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Retinopathy of prematurity (ROP), primarily affects premature infants and it can cause severe visual disability in childho- od.
📊
Key Findings & Data:It is characterized by anormal retinal neovascularizations and the main reason of blindness in children in developing countries.
💡
Conclusion & Impact:In this review we discuss risk factors, epidemiology, pathogenesis, screening and management of ROP
🔬Design:Experimental Field Trial
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Retinopathy of prematurity (ROP), primarily affects premature infants and it can cause severe visual disability in childho- od. It is characterized by anormal retinal neovascularizations and the main reason of blindness in children in developing countries. The well known risk factors are premature birth, low birth weight, high oxygen therapy ; the others are asidozis, blood transfusion, intracranial hemorrhage, multiple birhts and etnicity. The pathogenezis of ROP occurs in two phases. In the first phase there is relative hyperoxia and obliteration in vessels, in the second phase there is neovascularization which is induced by hypoxia. Neovascularization, occured by interruption of normal angiogenesis, reaches vitreus. Anormal fibro- vasküler doku develops and it causes retinal traction and detachment. In this review we discuss risk factors, epidemiology, pathogenesis, screening and management of ROP

Özet

Prematüre retinopatisi (PR), primer olarak zamanından önce doğan bebekleri etkileyen ve çucukluk çağında ağır görme kayıplarına yol açabilen bir hastalıktır. Anormal retinal neovaskülarizasyonla karekterize olup gelişmekte olan ülkelerde çocuklardaki körlüğün en önemli nedenidir. Erken doğum, yüksek oksijen konsantrasyonuna maruz kalmak, düşük doğum ağırlığına sahip olmak başta olmak üzere asidoz, kan transfüzyonu, intrakraniyal kanama, çoğul gebelik ve ırk hastalığın bilinen risk faktörleridir. Prematüre retinopatisi patogenezi iki fazdan oluşmaktadır. Birinci fazda relatif hiperoksi ve damarlarda obliterasyon olurken ikinci fazda hipoksinin tetiklediği neovaskülarizasyon mevcuttur. Normal anjiogenezisin kesintiye uğramasıyla oluşan yeni damarlar retinadan vitreusa doğru uzanır. Anormal fibrovasküler doku gelişimiyle retinal traksiyona ve dekolmana yol açar. Bu derlemede PR risk faktörleri, epidemiyolojisi, patogenezi, tanısı, tedavisi ve takibi tartışılmıştır.

🔖

Cite This Article

UZUNOVALI, B., ÖZTÜRK, A. Ö. (2013). Retinopathy of prematurity. Retina-Vitreus, Cilt: 21 - Sayı: 4, 314–319. https://ajindex.com/articles/305056

References (15)

  1. Tasman W, Patz A, Mc Namara JA. Retinopathy of prematurity: the life of a lifetime disease. Am J Ophthalmol 2006
  2. Rudonko SL, Felman V, Laatikaainen L. Visual impairment in children born prematurelyfrom 1972 trough 1989. Ophthalmol 2003
  3. Terry TL. Extreme prematurity and fibroblastic overgrowth of persistant vascular sheath behind each crystalline lens. I. Pre- liminary report. Am J Ophthalmol 1942
  4. Madan A, Good WV. Disorders of the eye. I: HW Taeussch, and RA Ballard (eds). Avery’s diseases of the newborn, 8th edition, Philadelphia, El sevier SAUNDERS, 2005
  5. Gilbert C, Fielder A, Gordillo L et al. On behalf of the inter- national NO-ROP Group.Characteristics of babies with severe retinopathy of prematurity in countries with low, modarate and high levels development:implications for screening programmes. Pediatr Electron Pages 2005
  6. Gilbert G,Rahi J, Eckstein M, O’Sullivan S, et al. Retinopathy of prematurity in middle income countries. Lancet 1997
  7. Arsan S. Prematüre retinopatisi. T Klin Pediatri 2004
  8. Wheeler DT, Dobson V, Chiang MF et al. Retinopathy of prema- turity in infants weighing less than 500 grams of birth enrolled in the early treatment for retinopathy of prematurity study. Ophthalmology. 2011
  9. Kaempf SW, Kaempf AJ, Wu Y et al. Hiperglisemia, insulin and slower growth velocity may increase the risk of retinopathy of prematurity. J. Perinatal. 2011
  10. Gunn DJ, Cartwright DW, Gole GA. Incidence of retinopathy of prematurity in extremely premature infants over an 18 years period. Clin Experiment Ophthalmol. 2012
  11. 40819:93-9. 11.Gergely K, Gerinec A. Retinopathy of prematurity epidem- ics, incidence, prevalance, blindness. Bratisl. LekListy. 2010
  12. Akçakaya A,Yaylalı SA, Erbil HH et al. Screening for retinopa- thy of prematurity in tertiary hospital in İstanbul: Incidence and risk factors. J Pediatr Opthalmol Strabismus. 2012
  13. Good WV, Hardy RJ, Dobson V et al. Early Ttreatment of Reti- nopathy Prematurity Cooperative Group. The incidence and course of retinopathy of prematurity: findings from the early treatment for retinopathy of prematurity study. Pediatrics 2005
  14. Gilbert C, Foster A. Childhood blindness in the context of vision 2020- the right to sight. Bull World Health Organ 2001
  15. Shih SC,Liu N,Smith LE. Selective stımulation of VEGF-1 pre- ventsoxygen-induced retinal vasküler dejenerat