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Journals / Glokom Katarakt / 2015 / Cilt: 10 - Sayı: 4

The Role of Micronutrition in Age-related Cataract and Glaucoma

Yaşa Bağlı Katarakt ve Glokomda Mikronütrisyonun Rolü

Berrin UZUNOVALI
Ayşe ÖZTÜRK ÖNER
Pages
312–316
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the role of antioxidants in the development of age-related cataract and glaucoma is discussed by scanning literature

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Free radicals which are occured by oxigen metabolizm damage cellular structure such as lipid, protein and DNA.
📊
Key Findings & Data:All cell membranes are rich in polyunsaturated fatty acids.
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Conclusion & Impact:In this review, the role of antioxidants in the development of age-related cataract and glaucoma is discussed by scanning literature
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Free radicals which are occured by oxigen metabolizm damage cellular structure such as lipid, protein and DNA. All cell membranes are rich in polyunsaturated fatty acids. Therefore they are easily damaged by oxidation. Antioxidants fight harmful affects of oxygen, control the free radicals, work on a fine balance between the formation and elimination of reactive oxigen spieces (ROS). When this balance fails, oxidative stress occurs. Oxidative stress is a cellular damage caused by ROS. It is responsible for pathogenesis of many diseases such as age-related macular degeneration, age-related cataract and glaucoma. In this review, the role of antioxidants in the development of age-related cataract and glaucoma is discussed by scanning literature

Özet

Oksijen metabolizması sonucu ortaya çıkan serbest radikaller lipit, protein, DNA gibi hücresel yapılara zarar verirler. Tüm hücre membranları poliansatüre yağ asitlerinden zengin olduğu için oksidasyondan kolayca hasarlanır. Antioksidanlar, oksijenin bu zararlı etkilerine karşı savaşırlar, serbest radikal oluşumunu kontrol altında tutarlar. Ancak bu denge bozulduğunda oksidatif stres ortaya çıkar. Oksidatif stres, reaktif oksijen parçalarının neden olduğu hücresel hasardır. Yaşa bağlı maküla dejenerasyonu başta olmak üzere yaşa bağlı katarakt ve glokom gibi birçok hastalığın patogenezinden sorumlu tutulmaktadır. Bu derlemede antioksidanların yaşa bağlı katarakt ve glokom gelişimindeki yeri literatür taramasıyla tartışılacaktır

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Cite This Article

UZUNOVALI, B., ÖNER, A. Ö. (2015). The Role of Micronutrition in Age-related Cataract and Glaucoma. Glokom Katarakt, Cilt: 10 - Sayı: 4, 312–316. https://ajindex.com/articles/201615

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