AI Summary & Key Takeaways
AI InsightThe need of thyrox-ine (T4) hormone increased with gestasional age.
📌 3 Key Takeaways
Abstract
The purpose of this study was to determine thyroid hormone levels of amniotic fluid and correlate with gestasional ages. Methods: 125 pregnant women underwent amniocentesis procedure for prenatal diagnosis were inclueded in study between May 2004 and May 2005. Thyroid hormone levels were analyzed with using Roche E170 Modular analytics (Hitachi, Japan) system. Statistical analyses were performed by using One-Way Anova test. A value of p<0.05 was considered statistically significant. Results: The mean age of patients was 34.5 + 5.6 (21-40) The mean gestational age of patients who underwent amniocentesis was 17.88 ± 1.58 (16-20) Karyotype analysis of all patients was normal. Amniotic fluid levels of total and free T4 increased progressively with gestasional age (p< 0.001). Although total T3 , free T3 and TSH levels did not increase with gestasional age (p>0.05). Conclusion: The levels of thyroxine (T4) hormone in amniotic fluid was higher than T3 and TSH hormones. The need of thyrox-ine (T4) hormone increased with gestasional age.
Özet
Amaç : Amniosentez uygulanan gebelerin amnion mayilerindeki tiroid hormon düzeylerini ölçmek ve bu değerlerin gestasyonel hafta ile olan ilişkisini değerlendirmek. Yöntem : Çalışmaya,Mayıs 2004 ile Mayıs 2005 tarihleri arasında prenatal tanı amacıyla,kliniğimizde amniosentez yapılan toplam 125 gebe dahil edildi.Tiroid hormon analizleri,1ml amnion sıvısında,Roche E170 Modular analytics (Hitachi,Japan) cihazı ile,Roche marka ticari kit kullanılarak gerçekleştirildi.Veriler,istatistiksel olarak One-Way Anova testi kullanılarak karşılaştırıldı,p 0.05). Sonuç : Amnion sıvısındaki tiroksin (T4) hormonun miktarının,T3 ve TSH’a göre daha fazla olduğunu bulduk ve bu hormona olan ihtiyacın gebelik haftası arttıkça belirginleştiğini düşünüyoruz.