SavedAdd your journal

Journals / Perinatoloji Dergisi / 2019 / Cilt: 27 - Sayı: 3

Early-onset neonatal sepsis and risk factors in the preterm infants

Preterm bebeklerde erken başlangıçlı sepsis ve risk faktörleri

Envera LEKİC
Sonja BABOVİC
Jelena VUKİCEVİC
Milorada NESOVİC
Ljubinka DRAGAS
Pages
143–149
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our data suggest that premature birth and low birth weight are the most common sepsis risk factors together with maternal preeclampsia, premature rupture of membrane and perinatal asphyxia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:and bacterial microorganisms causing early-onset sepsis in preterm newborn infants.
📊
Key Findings & Data:Methods: The open-label study was prospectively conducted from January to December 2015 in the University Clinical Center, Institute for Children’s Diseases, Center of Neonatology Podgorica, Montenegro.
💡
Conclusion & Impact:Conclusion: Our data suggest that premature birth and low birth weight are the most common sepsis risk factors together with maternal preeclampsia, premature rupture of membrane and perinatal asphyxia.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

and bacterial microorganisms causing early-onset sepsis in preterm newborn infants. Methods: The open-label study was prospectively conducted from January to December 2015 in the University Clinical Center, Institute for Children’s Diseases, Center of Neonatology Podgorica, Montenegro. Results: Out of 653 infants admitted (427 full-term, 226 preterm) the study included 71 infants diagnosed with sepsis (full-term infants with sepsis – 32 cases [7.5%] and preterm newborns with sepsis – 39 cases [17.3%]). Blood culture was positive in 44 newborns with sepsis (20 full-term, 24 preterm). Out of 24 preterm infants, early-onset sepsis was proven in 8 (dominant pathogen E. coli), and late-onset sepsis in 16 patients (dominant pathogens Klebsiella pneumoniae and Staphylococcus CoN). Premature birth and low birth weight were identified among the most common neonatal sepsis risk factors. Maternal preeclampsia, premature rupture of membrane and perinatal asphyxia were also identified as significant risk factors for early-onset neonatal sepsis in the preterm newborn infants. Conclusion: Our data suggest that premature birth and low birth weight are the most common sepsis risk factors together with maternal preeclampsia, premature rupture of membrane and perinatal asphyxia.

Özet

Amaç: Çal›flman›n amac›, preterm yenido¤an bebeklerde erken bafllang›çl› sepsise yol açan risk faktörlerini ve bakteriyel mikroorganizmalar› tespit etmekti. Yöntem: Aç›k uçlu çal›flma, Ocak–Aral›k 2015 tarihleri aras›nda Podgorica, Karada¤’daki Üniversite Klinik Merkezi, Çocuk Hastal› klar› Enstitüsü, Neonatoloji Merkezi’nde prospektif olarak yürütüldü. Bulgular: Çal›flmaya baflvuran 653 bebekten (427 miad, 226 preterm), sepsis tan›s› alm›fl 71 bebek (32 sepsisli miad yenido¤an [%7.5] ve 39 sepsisli preterm yenido¤an [%17.3]) çal›flmaya dahil edildi. Sepsisli 44 yenido¤anda kan kültürü sonucu pozitifti (20 miad, 24 preterm). Yirmi dört preterm bebekten, erken bafllang›çl› sepsis 8 olguda (dominant patojen E. coli) ve geç bafllang›çl› sepsis 16 olguda (dominant patojenler Klebsiella pneumoniae ve Staphylococcus CoN) tespit edildi. Prematüre do¤um ve düflük do¤um a¤›rl›¤›, neonatal sepsis için en yayg›n risk faktörleri olarak belirlendi. Maternal preeklampsi, erken membran rüptürü ve perinatal asfiksi de, preterm yenido¤an bebeklerde erken bafllang›çl› neonatal sepsis için önemli risk faktörleri olarak belirlendi. Sonuç: Verilerimiz, prematüre do¤um ve düflük do¤um a¤›rl›¤›- n›n, maternal preeklampsi, erken membran rüptürü ve perinatal asfiksi ile birlikte sepsis için en yayg›n risk faktörleri oldu¤unu göstermektedir.

🔖

Cite This Article

LEKİC, E., BABOVİC, S., VUKİCEVİC, J., NESOVİC, M., DRAGAS, L. (2022). Early-onset neonatal sepsis and risk factors in the preterm infants. Perinatoloji Dergisi, Cilt: 27 - Sayı: 3, 143–149. https://ajindex.com/articles/588352

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. World Health Organization. WHO Global Health Observatory (GHO) data. Causes of child mortality 2015. [Accessed 2016 July 04] [Internet]. Geneva: WHO Press; 2015. Available from: http://www.who.int/gho/child_health/ mortality/causes/en/ 2. World Health Organization. WHO Global Health Observatory (GHO) data. Neonatal mortality 2015. [Accessed 2016 July 01] [Internet]. Geneva: WHO Press; 2105. Available from: http:// www.who.int/gho/child_health/mortality/neonatal/en/ 3. Nizet V, Kelin JO, Bacterial sepsis and meningitis. In: Wilson CB, Nizet V, Maldonado YA, Remington JS, Kelin JO, editors. Remington and Klein’s infectious diseases of the fetus and newborn infant. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015. p. 217–90. 4. Edwards MS. Postnatal bacterial infections. In: Fanaroff A, Martin RJ, Walsh MC, editors. Neonatal - perinatal medicine. Diseases of the fetus and infant. 8th ed. St. Louis, MO; Mosby Elsevier; 2006. 793–829. 5. Cant AJ, Gennery AJ, Russell AB, Isaacs D. Neonatal infection. In: Rennie J, editor. Rennie & Roberton’s textbook of neonatology. 5th ed. St. Louis, MO; Elsevier; 2012. p. 1013– 42. 6. Ferrari P, Walen LD. Neonatal bacterial sepsis. Gleason CA, Devaskar SU, editors. Avery’s diseases of the newborn. 9th ed. Philadelphia, PA: Elsevier Saunders; 2012. p. 538–50. 7. Paolucci M, Landini MP, Sambri V. How can the microbiologist help in diagnosing neonatal sepsis? Int J Pediatr 2012; 2012:120139. 8. Pomerantz WJ, Weiss SL, Torrey SB, Kaplan SL, Randolph AG, Wiley JF. Systemic inflammatory response syndrome (SIRS) and sepsis in children: definitions, epidemiology, clinical manifestations, and diagnosis. Up To Date 2015;
  2. Waltham, MA. [Accessed on February 16th, 2015] 9. Argent AC. Recognizing pediatric sepsis: do the concepts help us to focus appropriately? Pediatr Crit Care Med 2016;17: 460–1. 10. Stool BJ, Shane AL. Infections of the neonatal infant. In: Kliegman S, Stanton BF, St. Geme JF III, Schor NF, editors. Nelson textbook of pediatrics. Vol. I. 20th ed. Philadelphia, PA: Elsevier Saunders; 2015. p. 909–25. 11. Isaacs D. Epidemiology. In: Isaacs D, editor. Evidence-based neonatal infections. Hoboken, NJ: Wiley; 2014. p. 5–10. 12. Embree JE, Alfattoh NI. Infections in the newborn. In: MacDonald MG, Seshia MM, editors. Avery’s neonatologypatophysiology and management of the newborn infant. 7th ed. Philadelphia, PA: Lippincott Company; 2015. p. 930–81. 13. Williams CB, Eisenstein EM, Cole SF. Immunology the fetus and newborn. I