Journals / Perinatoloji Dergisi / 2021 / Cilt: 29 - Sayı: 1

Evaluation of the impact of residual anhydramnios following preterm premature rupture of membranes on respiratory distress syndrome

Preterm erken membran rüptürü sonrası rezidüel anhidramniyozun respiratuvar distres sendromu üzerindeki etkisinin değerlendirilmesi

Pages
13–19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our results indicated that oligohydramnios and anhydramnios were not associated with RDS risk, but GA at PPROM and delivery, latency period, and cesarean delivery were independently associated with the RDS risk.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of the present study was to evaluate the impact of residual anhydramnios following preterm premature rupture of membranes (PPROM) on respiratory distress syndrome (RDS) after the pregnancy was expectantly managed.
📊
Key Findings & Data:It assessed women with singleton pregnancies admitted to the hospital between 2010 and 2020 for expectant management of PPROM between 24th and 28th gestational weeks.
💡
Conclusion & Impact:Conclusion: Our results indicated that oligohydramnios and anhydramnios were not associated with RDS risk, but GA at PPROM and delivery, latency period, and cesarean delivery were independently associated with the RDS risk.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the present study was to evaluate the impact of residual anhydramnios following preterm premature rupture of membranes (PPROM) on respiratory distress syndrome (RDS) after the pregnancy was expectantly managed. Methods: This study was retrospectively conducted at Erciyes University Medical School, Turkey. It assessed women with singleton pregnancies admitted to the hospital between 2010 and 2020 for expectant management of PPROM between 24th and 28th gestational weeks. The patients were divided into three groups as follows: (1) anhydramnios, (2) oligohydramnios, (3) normal amniotic fluid volume (AFV). Main outcome measure was as follows: The first evaluation was AFV at admission and the primary outcome was a neonatal RDS. Adjusted odds ratios (aOR) and 95% confidence interval (CI) for RDS were calculated for each AFV-at-presentation adjusting for gestational age (GA) at PPROM, GA at delivery, latency period, birth-weight percentile, cesarean birth, and chorioamnionitis. Results: Of the 440 women with PPROM, 261 fulfilled the inclusion criteria. There were 125 (47.8%) with normal AFV, 71 (27.3%) with oligohydramnios, and 65 (24.9%) with anhydramnios at admission. The maternal demographic characteristics were similar among the groups. Birth weight was significantly different among the groups. RDS was highest in the anhydramnios group (64.6%). Decreased AFV was not associated with RDS in either oligohydramnios or anhydramnios at presentation. A GA at PPROM, latency period >30 days, and cesarean delivery were co-factors in the outcome. Conclusion: Our results indicated that oligohydramnios and anhydramnios were not associated with RDS risk, but GA at PPROM and delivery, latency period, and cesarean delivery were independently associated with the RDS risk.

Özet

Amaç: Çalışmamızın amacı, gebeliğin yakın izlem şekilde yönetilmesinden sonra preterm erken membran rüptürü sonrası rezidüel anhidramniyozun respiratuvar distres sendromu (RDS) üzerindeki etkisini değerlendirmekti. Yöntem: Bu çalışma, Erciyes Üniversitesi Tıp Fakültesinde ret rospektif olarak gerçekleştirildi. Çalışmada, gebeliğin 24 ile 28. haftaları arasında yakın izlem PEMR yönetimi için 2010 ile 2020 yılları arasında hastaneye başvuran tekil gebelik olguları değerlendirildi. Hastalar şu üç gruba ayrıldı: (1) anhidramniyoz, (2) oligo hidramniyoz, (3) normal amniyotik sıvı hacmi (ASH). Ana sonuç ölçümleri ilk değerlendirme başvurudaki ASH iken birincil sonuç neonatal RDS idi. RDS için düzeltilmiş olasılık oranları (aOR) ve %95 güven aralığı (GA); PEMR’de gestasyonel yaş (GY), doğum da GY, gecikme dönemi, doğum ağırlığı persantili, sezaryen doğum ve koryoamniyonit bakımından düzeltilen her bir başvuruda ki ASH için hesaplandı. Bulgular: PEMR’li 440 kadının 261’i çalışmaya dahil olma kriterlerini karşıladı. Başvuruda normal ASH’li 125 (%47.8) olgu, oligo hidramniyozlu 71 (%27.3) olgu ve anhidramniyozlu 65 (%24.9) olgu vardı. Maternal demografik özellikler, gruplar arasında benzerdi. Doğum ağırlığı, gruplar arasında anlamlı şekilde farklıydı. RDS, anhidramniyoz grubunda en yüksek seviyedeydi (%64.6). Azalmış ASH, başvuruda oligohidramniyoz veya anhidramniyoz grubunda RDS ile ilişkili değildi. PEMR’de GY, 30 günden büyük gecikme dönemi ve sezaryen doğum, sonuçta ortak faktörlerdi. Sonuç: Sonuçlarımız, oligohidramniyoz ve anhidramniyozun RDS riskiyle ilişkili olmadığını, fakat PEMR ve doğumda GY’nin, gecikme döneminin ve sezaryen doğumun bağımsız olarak RDS riskiyle ilişkili olduğunu göstermektedir.

🔖

Cite This Article

ŞAHİN, E., MADENDAĞ, Y. (2021). Evaluation of the impact of residual anhydramnios following preterm premature rupture of membranes on respiratory distress syndrome. Perinatoloji Dergisi, Cilt: 29 - Sayı: 1, 13–19. https://ajindex.com/articles/300271

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Ekin A, Gezer C, Taner CE, Özeren M. Perinatal outcomes in pregnancies with oligohydramnios after preterm premature rupture of membranes. J Matern Fetal Neonatal Med 2015
  2. 1918–22. [PubMed] [CrossRef] 2. Storness-Bliss C, Metcalfe A, Simrose R, Wilson RD, Cooper SL. Correlation of residual amniotic fluid and perinatal outcomes in periviable preterm premature rupture of membranes. J Obstet Gynaecol Can 2012
  3. 154–8. [PubMed] [CrossRef] 3. Hasegawa J, Ikeda T, Sekizawa A, Ishiwata I, Kinoshita K
  4. Japan Association of Obstetricians and Gynecologists, Tokyo, Japan. Obstetric risk factors for umbilical cord prolapse: a nationwide population-based study in Japan. Arch GynecolObstet 2016
  5. 467–72. [PubMed] [CrossRef] 4. Lewis DF, Robichaux AG, Jaekle RK, Salas A, Canzoneri BJ, Horton K, et al. Expectant management of preterm premature rupture of membranes and nonvertex presentation: what are the risks? Am J Obstet Gynecol 2007
  6. e1–5. [PubMed] [CrossRef] 5. Sahin E, Madendag Y, Tayyar AT, Sahin ME, Madendag IC, Acmaz G. Perinatal outcomes in uncomplicated late preterm pregnancies with borderline oligohydramnios. J Matern Fetal Neonatal Med. 2018
  7. 3085–8. [PubMed] [CrossRef] 6. Wu CS, Chen CM, Chou HC. Pulmonary hypoplasia induced by oligohydramnios: findings from animal models and a population-based study. Pediatr Neonatol 2017
  8. 3– 7. [PubMed] [CrossRef] 7. Winn HN, Chen M, Amon E, Leet TL, Shumway JB, Mostello D. Neonatal pulmonary hypoplasia and perinatal mortality in patients with midtrimester rupture of amniotic membranes – a critical analysis. Am J Obstet Gynecol 2000
  9. 1638–44. [PubMed] [CrossRef] 8. Williams O, Michel B, Hutchings G, Debauche C, Hubinont C. Two-year neonatal outcome following PPROM prior to 25 weeks with a prolonged period of oligohydramnios. Early Hum Dev 2012
  10. 657–61. [PubMed] [CrossRef] 9. Kotecha S. Lung growth: implications for the newborn infant. Arch Dis Child Fetal Neonatal Ed 2000
  11. F69–74. [PubMed] [CrossRef] 10. Saker F, Martin R. Pathophysiology and clinical manifestations of respiratory distress syndrome in the newborn. Garcia-Prats JA, editor. Waltham (MA): Up-To-Date [database on the internet]
  12. Available from: http://www.uptodate.com 11. Kamath BD, MacGuire ER, McClure EM, Goldenberg RL, Jobe AH. Neonatal mortality from respiratory distress syndrome: lessons for low-resource countries. Pediatrics 2011
  13. 1139–46. [PubMed] [CrossRef] 12. Madendag Y, Madendag IC, Sahin E, Aydin E, Sahin ME, Acma