Journals / Perinatoloji Dergisi / 2021 / Cilt: 29 - Sayı: 1

Evaluation of epicardial fat tissue thickness and aortic stiffness in patients with gestational diabetes mellitus

Gestasyonel diabetes mellitus hastalarında epikardiyal yağ dokusu kalınlığı ve aortik sertliğin değerlendirilmesi

Pages
33–38
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: According to the results of our study, epicardial fat tissue thickness was found to be statistically significantly higher in pregnant women with gestational diabetes mellitus compared to the control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to assess the relationship between gestational diabetes mellitus and coronary artery disease by measuring epicardial fat tissue thickness and aortic stiffness in pregnant women diagnosed with gestational diabetes mellitus.
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Key Findings & Data:Methods: 28 pregnant women diagnosed with gestational diabetes mellitus and 25 pregnant women without gestational diabetes mellitus were included in the research.
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Conclusion & Impact:Conclusion: According to the results of our study, epicardial fat tissue thickness was found to be statistically significantly higher in pregnant women with gestational diabetes mellitus compared to the control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to assess the relationship between gestational diabetes mellitus and coronary artery disease by measuring epicardial fat tissue thickness and aortic stiffness in pregnant women diagnosed with gestational diabetes mellitus. Methods: 28 pregnant women diagnosed with gestational diabetes mellitus and 25 pregnant women without gestational diabetes mellitus were included in the research. Body mass index, laboratory values, blood pressure measurements and obstetric history findings of the study population were recorded. All participants of the study population were evaluated with transthoracic echocardiography between 24 and 28 weeks of gestational period. The measurement of epicardial fat tissue thickness was taken and aortic stiffness index was also calculated. Results: The age, gravidity, parity and obstetric history of the two groups were similar. Epicardial fat tissue thickness was found significantly higher in gestational diabetes mellitus group than control group (0.416 cm and 0.336 cm, respectively; p<0.001). However, no significant difference was found in aortic stiffness measurements of the two groups (p=0.079). Conclusion: According to the results of our study, epicardial fat tissue thickness was found to be statistically significantly higher in pregnant women with gestational diabetes mellitus compared to the control group. The fact that no difference was detected in other cardiovascular parameters suggests that measurement of epicardial fat tissue thickness in gestational period may be a beneficial adjunctive tool in early detection of gestational diabetes mellitus.

Özet

Amaç: Çalışmamızda, gestasyonel diabetes mellitus tanısı almış gebelerde epikardiyal yağ dokusu kalınlığını ve aortik sertliği ölçerek gestasyonel diabetes mellitus ile koroner arter hastalığı arasındaki ilişkiyi değerlendirmeyi amaçladık. Yöntem: Çalışmaya gestasyonel diabetes mellitus tanısı almış 28 gebe ve gestasyonel diabetes mellitusu olmayan 25 gebe dahil edildi. Çalışma popülasyonunun vücut kitle indeksi, laboratuvar değerleri, kan basıncı ölçümleri ve obstetrik hikaye bulguları kaydedildi. Çalışmaya katılan tüm olgular gebeliğin 24 ve 25. haftaları arasında transtorasik ekokardiyografi ile değerlendirildi. Epikardiyal yağ dokusu kalınlığı ölçümü alındı ve aortik sertlik indeksi hesaplandı. Bulgular: Yaş, gravida, parite ve obstetrik hikaye bakımından iki grup benzerdi. Epikardiyal yağ dokusu kalınığı, kontrol grubuna kıyasla gestasyonel diabetes mellitus grubunda anlamlı şekilde daha yüksekti (sırasıyla 0.336 cm ve 0.416 cm; p<0.001). Ancak, iki grubun aortik sertlik ölçümleri arasında hiçbir anlaml› fark yoktu (p=0.079). Sonuç: Çalışmamızın sonuçlarına göre epikardiyal yağ dokusu kalınlığı, kontrol grubuna kıyasla gestasyonel diabetes mellituslu gebelerde istatistiksel olarak anlamlı şekilde daha yüksekti. Diğer kardiyovasküler parametrelerde hiçbir farklılığın bulunmaması, gestasyonel dönemde epikardiyal yağ dokusu kalınlığı ölçümünün gestasyonel diabetes mellitusun erken tespitinde faydalı bir ek araç olabileceğine işaret etmektedir.

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Cite This Article

AKIN, M. N., KASAP, B., AKIN, F., SEZGİN, B., ALTUN, İ., CAMUZCUĞLU, A., DEVEER, R., TURHAN, N. Ö. (2021). Evaluation of epicardial fat tissue thickness and aortic stiffness in patients with gestational diabetes mellitus. Perinatoloji Dergisi, Cilt: 29 - Sayı: 1, 33–38. https://ajindex.com/articles/300267

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References (1)

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