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Journals / MN Kardiyoloji / 2006 / Cilt: 13 - Sayı: 3

The evaluation of mean platelet volume and platelet count in patients with acute myocardial infarction

Akut miyokard infarktüslü hastalarda ortalama trombosit hacmi ve trombosit sayısının değerlendirilmesi

Neslihan AKBULUT
Mustafa YILDIZ
Şahin Banu YILDIZ
Songül AKTAŞ
Mustafa YAYLACI
Pages
180–185
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As a results, it is shown that there is an increase in mean platelet volume and a decrease in platelet count in acute myocardial infarction.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Platelet aggregation plays an important role in the pathogenesis of acute myocardial infarction.
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Key Findings & Data:Material and Method: Sixty-two patients with acute myocardial infarction (24 women, mean age: 57.9±9.4 years) and 66 control subjects (28 women, mean age: 57.9±9.4 years) were studied.
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Conclusion & Impact:Conclusion: As a results, it is shown that there is an increase in mean platelet volume and a decrease in platelet count in acute myocardial infarction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Miyokard enfarktüsü · İnterlökin-6 · Trombosit sayısı

Abstract

Aim: Platelet aggregation plays an important role in the pathogenesis of acute myocardial infarction. Platelet size is a determinant of platelet function. Large platelets are hemostatically active and may have a role in the formation of intracoronary thrombosis and acute myocardial infarction. In this study, the changes in mean platelet volume and platelet count were investigated in patients with acute myocardial infarction. Material and Method: Sixty-two patients with acute myocardial infarction (24 women, mean age: 57.9±9.4 years) and 66 control subjects (28 women, mean age: 57.9±9.4 years) were studied. Blood samples for platelet count and mean platelet volume were obtained from the patients with acute myocardial infarction on admission and from control group during routine evaluation. Results: Mean platelet volume was higher in patients with acute myocardial infarction (10.49±0.87 fl) compared to control group (9.79±0.50 fl) (p<0.001). Platelet count was significantly lower in patients with acute myocardial infarction (215341.8±60879.68/mm3) compared to control group (271727.3±49169.57/mm3) (p<0.001). Conclusion: As a results, it is shown that there is an increase in mean platelet volume and a decrease in platelet count in acute myocardial infarction.

Özet

Amaç: Trombosit agregasyonu, akut miyokard infarktüs patogenezinde önemli bir rol oynar. Trombosit büyüklüğü, trom­bosit fonsiyonunun bir belirtecidir. Büyük trombosit hemostatik olarak aktif olup, akut miyokard infarktüsü ve int­rakoroner trombüs formasyonunda rol alabilir. Bu çalışmada akut miyokard infarktüslü hastalarda ortalama trom­bosit hacmi ve trombosit sayısındaki değişiklikler araştırıldı. Gereç ve Yöntem: Çalışmaya 62 (24 kadın, yaş ortalaması: 57.9±9.4 yıl) akut miyokard infarktüslü hasta ve 66 (28 kadın, yaş ortalaması: 56.8±8.5 yıl) sağlıklı kontrol grubu dahil edildi. Trombosit sayısı ve hacmi için kan ör­nek­le­ri akut miyokard infarktüslü hastalarda hastaneye başvuruşlarında, diğer olgularda ise hastaların rutin takiplerinde alın­dı. Bulgular: Akut miyokard infarktüslü hasta grubunda trombosit sayısı kontrol grubuna göre daha düşükken (215341.8±60879.68/mm3’e karşı 271727.3 ± 49169.57/mm3, p<0.001); kontrol grubunda ortalama trombosit hacmi akut miyokard infarktüslü hasta grubundan daha düşüktü (9.79 ± 0.50 fl’e karşı 10.49 ± 0.87 fl, p<0.001). Sonuç: Akut miyokard infarktüslü hastalarda ortalama trombosit hacmi artarken; trombosit sayısı azalmaktadır.

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Cite This Article

AKBULUT, N., YILDIZ, M., YILDIZ, Ş. B., AKTAŞ, S., YAYLACI, M. (2006). The evaluation of mean platelet volume and platelet count in patients with acute myocardial infarction. MN Kardiyoloji, Cilt: 13 - Sayı: 3, 180–185. https://ajindex.com/articles/299192

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